Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages von Kim, Baek, Nguyen, Laura A., Daddacha, Waaqo, Hollenbaugh, Joseph A.

Volltext

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response von Behrendt, Rayk, Schumann, Tina, Gerbaulet, Alexander, Nguyen, Laura A., Schubert, Nadja, Alexopoulou, Dimitra, Berka, Ursula, Lienenklaus, Stefan, Peschke, Katrin, Gibbert, Kathrin, Wittmann, Sabine, Lindemann, Dirk, Weiss, Siegfried, Dahl, Andreas, Naumann, Ronald, Dittmer, Ulf, Kim, Baek, Mueller, Werner, Gramberg, Thomas, Roers, Axel

Volltext

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2- d ]pyrimidine non-nucleoside inhibitors von Yang, Yang, Kang, Dongwei, Nguyen, Laura A, Smithline, Zachary B, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong, Steitz, Thomas A

Volltext

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells von Zhang, Ruonan, Bloch, Nicolin, Nguyen, Laura A, Kim, Baek, Landau, Nathaniel R

Volltext

SAMHD1 prevents autoimmunity by maintaining genome stability von Kretschmer, Stefanie, Wolf, Christine, König, Nadja, Staroske, Wolfgang, Guck, Jochen, Häusler, Martin, Luksch, Hella, Nguyen, Laura A, Kim, Baek, Alexopoulou, Dimitra, Dahl, Andreas, Rapp, Alexander, Cardoso, M Cristina, Shevchenko, Anna, Lee-Kirsch, Min Ae

Volltext

Crystal structure of Pistol, a class of self-cleaving ribozyme von Nguyen, Laura A., Wang, Jimin, Steitz, Thomas A.

Volltext

SAMHD1 prevents autoimmunity by maintaining genome stability von Kretschmer, Stefanie, Wolf, Christine, König, Nadja, Staroske, Wolfgang, Guck, Jochen, Häusler, Martin, Luksch, Hella, Nguyen, Laura A, Kim, Baek, Alexopoulou, Dimitra, Dahl, Andreas, Rapp, Alexander, Cardoso, M Cristina, Shevchenko, Anna, Lee-Kirsch, Min Ae

Volltext

Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect von Bhattacharya, Akash, Wang, Zhonghua, White, Tommy, Buffone, Cindy, Nguyen, Laura A., Shepard, Caitlin N., Kim, Baek, Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N.

Volltext

Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells von Baldauf, Hanna-Mari, Stegmann, Lena, Schwarz, Sarah-Marie, Ambiel, Ina, Trotard, Maud, Martin, Margarethe, Burggraf, Manja, Lenzi, Gina M., Lejk, Helena, Pan, Xiaoyu, Fregoso, Oliver I., Lim, Efrem S., Abraham, Libin, Nguyen, Laura A., Rutsch, Frank, König, Renate, Kim, Baek, Emerman, Michael, Fackler, Oliver T., Keppler, Oliver T.

Volltext

Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1 von Wang, Zhonghua, Bhattacharya, Akash, White, Tommy, Buffone, Cindy, McCabe, Aine, Nguyen, Laura A., Shepard, Caitlin N., Pardo, Sammy, Kim, Baek, Weintraub, Susan T., Demeler, Borries, Diaz-Griffero, Felipe, Ivanov, Dmitri N.

Volltext

Host SAMHD1 Protein Promotes HIV-1 Recombination in Macrophages von Nguyen, Laura A., Kim, Dong-Hyun, Daly, Michele B., Allan, Kevin C., Kim, Baek

Volltext

Effect of Ribonucleotides Embedded in a DNA Template on HIV-1 Reverse Transcription Kinetics and Fidelity von Daddacha, Waaqo, Noble, Erin, Nguyen, Laura A., Kennedy, Edward M., Kim, Baek

Volltext

Altered Strand Transfer Activity of a Multiple-Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutant with a Dipeptide Fingers Domain Insertion von Nguyen, Laura A., Daddacha, Waaqo, Rigby, Sean, Bambara, Robert A., Kim, Baek

Volltext

Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA te... von Nguyen, Laura A., Domaoal, Robert A., Kennedy, Edward M., Kim, Dong-Hyun, Schinazi, Raymond F., Kim, Baek

Volltext

HIV-1 Reverse Transcriptase Dissociates during Strand Transfer von Muchiri, John M., Rigby, Sean T., Nguyen, Laura A., Kim, Baek, Bambara, Robert A.

Volltext

Crystal structure of Pistol, a class of self von Nguyen, Laura A, Wang, Jimin, Steitz, Thomas A

Volltext

Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d] pyrimidine non-nucleoside inhibitors von Yang, Yang, Kang, Dongwei, Nguyen, Laura A, Smithline, Zachary B, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong, Steitz, Thomas A

Volltext

Host SAMHD1 protein promotes HIV-1 recombination in macrophages von Nguyen, Laura A., Kim, Dong-Hyun, Daly, Michele B., Allan, Kevin C., Kim, Baek

Volltext

Altered Strand Transfer Activity of a Multi-drug-resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutant with a Dipeptide Fingers Domain Insertion von Nguyen, Laura A., Daddacha, Waaqo, Rigby, Sean, Bambara, Robert A., Kim, Baek

Volltext

SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells: e89558 von Zhang, Ruonan, Bloch, Nicolin, Nguyen, Laura A, Kim, Baek, Landau, Nathaniel R

Volltext