Fine-Scale Mapping of a Locus for Severe Bipolar Mood Disorder on Chromosome 18p11.3 in the Costa Rican Population von McInnes, L. Alison, Service, Susan K., Reus, Victor I., Barnes, Glenn, Charlat, Olga, Jawahar, Satya, Lewitzky, Steve, Yang, Qing, Duong, Quyen, Spesny, Mitzi, Araya, Carmen, Araya, Xinia, Gallegos, Alvaro, Meza, Luis, Molina, Julio, Ramirez, Rolando, Mendez, Roxana, Silva, Sandra, Fournier, Eduardo, Batki, Steven L., Mathews, Carol A., Neylan, Thomas, Glatt, Charles E., Escamilla, Michael A., Luo, David, Gajiwala, Paresh, Song, Terry, Crook, Stephen, Nguyen, Jasmine B., Roche, Erin, Meyer, Joanne M., Leon, Pedro, Sandkuijl, Lodewijk A., Freimer, Nelson B., Chen, Hong

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Assessing the Feasibility of Linkage Disequilibrium Methods for Mapping Complex Traits: An Initial Screen for Bipolar Disorder Loci on Chromosome 18 von Escamilla, Michael A., McInnes, L. Alison, Spesny, Mitzi, Reus, Victor I., Service, Susan K., Shimayoshi, Norito, Tyler, David J., Silva, Sandra, Molina, Julio, Gallegos, Alvaro, Meza, Luis, Cruz, Maria L, Batki, Steven, Vinogradov, Sophia, Neylan, Thomas, Nguyen, Jasmine B., Fournier, Eduardo, Araya, Carmen, Barondes, Samuel H., Leon, Pedro, Sandkuijl, Lodewijk A., Freimer, Nelson B.

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Signal Transduction Strategies for Analyte Detection Using DNA‐Based Nanostructures von Lee, Seungheon, Godhulayyagari, Shivudu, Nguyen, Shadler T., Lu, Jasmine K., Ebrahimi, Sasha B., Samanta, Devleena

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Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation von Russ, Brendan E., Olshanksy, Moshe, Smallwood, Heather S., Li, Jasmine, Denton, Alice E., Prier, Julia E., Stock, Angus T., Croom, Hayley A., Cullen, Jolie G., Nguyen, Michelle L.T., Rowe, Stephanie, Olson, Matthew R., Finkelstein, David B., Kelso, Anne, Thomas, Paul G., Speed, Terry P., Rao, Sudha, Turner, Stephen J.

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Fucosylated Human Milk Oligosaccharide Foraging within the Species Bifidobacterium pseudocatenulatum Is Driven by Glycosyl Hydrolase Content and Specificity von Shani, Guy, Hoeflinger, Jennifer L, Heiss, Britta E, Masarweh, Chad F, Larke, Jules A, Jensen, Nick M, Wickramasinghe, Saumya, Davis, Jasmine C, Goonatilleke, Elisha, El-Hawiet, Amr, Nguyen, Linh, Klassen, John S, Slupsky, Carolyn M, Lebrilla, Carlito B, Mills, David A

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Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes von Al-Azzam, Norah, To, Jenny H., Gautam, Vaishali, Street, Lena A., Nguyen, Chloe B., Naritomi, Jack T., Lam, Dylan C., Madrigal, Assael A., Lee, Benjamin, Jin, Wenhao, Avina, Anthony, Mizrahi, Orel, Mueller, Jasmine R., Ford, Willard, Schiavon, Cara R., Rebollo, Elena, Vu, Anthony Q., Blue, Steven M., Madakamutil, Yashwin L., Manor, Uri, Rothstein, Jeffrey D., Coyne, Alyssa N., Jovanovic, Marko, Yeo, Gene W.

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Evaluation of Macitentan in Patients With Eisenmenger Syndrome: Results From the Randomized, Controlled MAESTRO Study von Landzberg, Michael, Beghetti, Maurice, Berger, Rolf M, Efficace, Michela, Gesang, Sophie, He, Jian’guo, Papadakis, Kelly, Galiè, Nazzareno, Lang, Irene, Delcroix, Marion, Vachiéry, Jean-Luc, Tzonzarova, Margarita, Georgiev, Borislav, Velchev, Vasil, Yotov, Yoto, Grewal, Jasmine, Lien, Dale, Varela, Pablo Sepulveda, Uriarte, Polentzi, Yao, Hua, Gu, Hong, Zhang, Gangcheng, Zhu, Xianyang, Popelová, Jana, Jansa, Pavel, Špinar, Jindřich, Aldebert, Philippe, Guérin, Patrice, Thambo, Jean-Benoit, Iserin, Laurence, Khalil, Markus, Diller, Gerhard-Paul, Kaemmerer, Harald, Gorenflo, Matthias, Miera, Oliver, Rammos, Spyridon, Karvounis, Haralampos, Forster, Tamás, Kramer, Mordechai, Adir, Yochai, Ghio, Stefano, Chew, David Soon Ping, Zamudio, Tomas Rene Pulido, Alva, Juan Carlos Perez, Sanchez, Carlos Jerjes, Orellana, Julio Erdmenger, Mateo, Ma Paz B, Hoffman, Piotr, Podolec, Piotr, Lewczuk, Jerzy, Gąsior, Zbigniew, Raczak, Grzegorz, Mularek-Kubzdela, Tatiana, Figueiredo Agapito, Ana María, de Oliveira Castro, Maria da Graça Calado, Coman, Ioan Mircea, Bertici, Nicoleta Sorina, Nicoleta Benedek, Theodora Mariana, Moiseeva, Olga M, Popov, Sergey, Barbarash, Olga, Martynyuk, Tamila, Tošić, Biljana Putniković, Korac, Natasa Stokuca, Kosutic, Jovan, Herbst, Phillipus, Essop, Mohammed Rafique, Brown, Stephen, Escribano, Pilar, Cubero, Javier Segovia, Gallego, Pastora, Subira, Laura Dos, Fernández-Avilés Díaz, Francisco, Soriano, Joaquín Rueda, Hsu, Hsao-Hsun, Wang, Kuo-Yang, Hsieh, Kai-Sheng, Alehan, Dursun, Kucukoglu, Serdar, Tunaoğlu, Sedef, Baysal, Kemal, Tulloh, Robert M R, Mahadevan, Vaikon, Franklin, Wayne J, Krasuski, Richard, Opotowsky, Alexander, Rosenzweig, Erika, Aboulhosn, Jamil, Book, Wendy, Daniels, Curt, Cedars, Ari, Chakinala, Murali, Rothman, Abraham, Fisher, Stacy, Romfh, Anitra W, Kay, Joseph, Oudiz, Ronald, Nguyen, Lan Hieu, Do, Nguyen Tin, Pham, Nguyen Vinh

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Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse: The OPTIMAL Randomized Trial von Barber, Matthew D, Brubaker, Linda, Burgio, Kathryn L, Richter, Holly E, Nygaard, Ingrid, Weidner, Alison C, Menefee, Shawn A, Lukacz, Emily S, Norton, Peggy, Schaffer, Joseph, Nguyen, John N, Borello-France, Diane, Goode, Patricia S, Jakus-Waldman, Sharon, Spino, Cathie, Warren, Lauren Klein, Gantz, Marie G, Meikle, Susan F

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Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus von Cross, Robert W, Woolsey, Courtney, Chu, Victor C, Babusis, Darius, Bannister, Roy, Vermillion, Meghan S, Geleziunas, Romas, Barrett, Kimberly T, Bunyan, Elaine, Nguyen, Anh-Quan, Cihlar, Tomas, Porter, Danielle P, Prasad, Abhishek N, Deer, Daniel J, Borisevich, Viktoriya, Agans, Krystle N, Martinez, Jasmine, Harrison, Mack B, Dobias, Natalie S, Fenton, Karla A, Bilello, John P, Geisbert, Thomas W

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Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys von Mackman, Richard L., Kalla, Rao V., Babusis, Darius, Pitts, Jared, Barrett, Kimberly T., Chun, Kwon, Du Pont, Venice, Rodriguez, Lauren, Moshiri, Jasmine, Xu, Yili, Lee, Michael, Lee, Gary, Bleier, Blake, Nguyen, Anh-Quan, O’Keefe, B. Michael, Ambrosi, Andrea, Cook, Meredith, Yu, Joy, Dempah, Kassibla Elodie, Bunyan, Elaine, Riola, Nicholas C., Lu, Xianghan, Liu, Renmeng, Davie, Ashley, Hsiang, Tien-Ying, Dearing, Justin, Vermillion, Meghan, Gale, Michael, Niedziela-Majka, Anita, Feng, Joy Y., Hedskog, Charlotte, Bilello, John P., Subramanian, Raju, Cihlar, Tomas

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Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites von Tokarew, Jacqueline M., El-Kodsi, Daniel N., Lengacher, Nathalie A., Fehr, Travis K., Nguyen, Angela P., Shutinoski, Bojan, O’Nuallain, Brian, Jin, Ming, Khan, Jasmine M., Ng, Andy C. H., Li, Juan, Jiang, Qiubo, Zhang, Mei, Wang, Liqun, Sengupta, Rajib, Barber, Kathryn R., Tran, An, Im, Doo Soon, Callaghan, Steve, Park, David S., Zandee, Stephanie, Dong, Xiajun, Scherzer, Clemens R., Prat, Alexandre, Tsai, Eve C., Takanashi, Masashi, Hattori, Nobutaka, Chan, Jennifer A., Zecca, Luigi, West, Andrew B., Holmgren, Arne, Puente, Lawrence, Shaw, Gary S., Toth, Gergely, Woulfe, John M., Taylor, Peggy, Tomlinson, Julianna J., Schlossmacher, Michael G.

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ASO Visual Abstract: How Protective are Nipple-Sparing Prophylactic Mastectomies in BRCA1 and BRCA2 Mutation Carriers? von Garstka, Meghan, Henriquez, Anthony, Kelly, Bridget N., Webster, Alexandra, Khubchandani, Jasmine A., Hughes, Kevin, Nguyen, Anvy, Oseni, Tawakalitu, Specht, Michelle, Coopey, Suzanne B., Gadd, Michele A., Smith, Barbara L.

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Su1264 THE PREVALENCE OF PERSISTENT BARRETT'S ESOPHAGUS AFTER ULTRASHORT BARRETT'S DIAGNOSIS IS HIGH AND HARBORS DYSPLASIA RISK von Haydel, Jasmine, Nguyen, Theresa H., Rao, Ashwin, Allencherril, Ronan, Ketwaroo, Gyanprakash, George, Rollin, Thrift, Aaron P., El-Serag, Hashem B., Skef, Wasseem

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity von House, Imran G., Derrick, Emily B., Sek, Kevin, Chen, Amanda X.Y., Li, Jasmine, Lai, Junyun, Todd, Kirsten L., Munoz, Isabelle, Michie, Jessica, Chan, Cheok Weng, Huang, Yu-Kuan, Chan, Jack D., Petley, Emma V., Tong, Junming, Nguyen, DatMinh, Engel, Sven, Savas, Peter, Hogg, Simon J., Vervoort, Stephin J., Kearney, Conor J., Burr, Marian L., Lam, Enid Y.N., Gilan, Omer, Bedoui, Sammy, Johnstone, Ricky W., Dawson, Mark A., Loi, Sherene, Darcy, Phillip K., Beavis, Paul A.

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Cholecystectomy in patients with hematologic malignancies von Stewart, Camille L., Tran, Thuy B., Nguyen, Andrew, Zain, Jasmine, Lai, Lily, Fong, Yuman, Woo, Yanghee

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy von Chan, Jack D., Scheffler, Christina M., Munoz, Isabelle, Sek, Kevin, Lee, Joel N., Huang, Yu-Kuan, Yap, Kah Min, Saw, Nicole Y. L., Li, Jasmine, Chen, Amanda X. Y., Chan, Cheok Weng, Derrick, Emily B., Todd, Kirsten L., Tong, Junming, Dunbar, Phoebe A., Li, Jiawen, Hoang, Thang X., de Menezes, Maria N., Petley, Emma V., Kim, Joelle S., Nguyen, Dat, Leung, Patrick S. K., So, Joan, Deguit, Christian, Zhu, Joe, House, Imran G., Kats, Lev M., Scott, Andrew M., Solomon, Benjamin J., Harrison, Simon J., Oliaro, Jane, Parish, Ian A., Quinn, Kylie M., Neeson, Paul J., Slaney, Clare Y., Lai, Junyun, Beavis, Paul A., Darcy, Phillip K.

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A Multicenter Study of Left Ventricular Assist Device-Related Gastrointestinal Bleeding von Dailey, Joseph, Nguyen, Long H., Kohli, Arushi, Ha, Jasmine B., Russell, Michael B., Dhingra, Rohit, Kiernan, Michael S., Thomas, Molly F., Coglianese, Erin C., Sterling, Mark J., Yacavone, Robert F., Natov, Nikola, Richter, James M.

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SP55. Leveraging AI’s Potential: Real-Time Prediction Of Longitudinal Patient Development Using Imaging Data von Elkhill, Connor, Chaij, Jasmine, LeBeau, Scott, Khechoyan, David, Nguyen, Phuong, French, Brooke, Porras, Antonio

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Identifying cis -mediators for trans -eQTLs across many human tissues using genomic mediation analysis von Yang, Fan, Wang, Jiebiao, Pierce, Brandon L, Chen, Lin S

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A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism von Ptacin, Jerod L., Ma, Lina, Caffaro, Carolina E., Acuff, Nicole V., Germar, Kristine, Severy, Peter, Qu, Yanyan, Vela, Jose-Luis, Cai, Xinming, San Jose, Kristine M., Aerni, Hans R., Chen, David B., Esche, Ean, Ismaili, Taylor K., Herman, Rob, Pavlova, Yelena, Pena, Michael J., Nguyen, Jasmine, Koriazova, Lilia K., Shawver, Laura K., Joseph, Ingrid B., Mooney, Jill, Peakman, Mark, Milla, Marcos E.

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