Building confidence in circulating tumour DNA assays for metastatic castration-resistant prostate cancer von Ng, Sarah W. S., Wyatt, Alexander W.

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A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes von Ritch, Elie J., Herberts, Cameron, Warner, Evan W., Ng, Sarah W. S., Kwan, Edmond M., Bacon, Jack V. W., Bernales, Cecily Q., Schönlau, Elena, Fonseca, Nicolette M., Giri, Veda N., Maurice-Dror, Corinne, Vandekerkhove, Gillian, Jones, Steven J. M., Chi, Kim N., Wyatt, Alexander W.

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Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer von Herberts, Cameron, Annala, Matti, Sipola, Joonatan, Ng, Sarah W. S., Chen, Xinyi E., Nurminen, Anssi, Korhonen, Olga V., Munzur, Aslı D., Beja, Kevin, Schönlau, Elena, Bernales, Cecily Q., Ritch, Elie, Bacon, Jack V. W., Lack, Nathan A., Nykter, Matti, Aggarwal, Rahul, Small, Eric J., Gleave, Martin E., Quigley, David A., Feng, Felix Y., Chi, Kim N., Wyatt, Alexander W.

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Early On-treatment Changes in Circulating Tumor DNA Fraction and Response to Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer von Tolmeijer, Sofie H, Boerrigter, Emmy, Sumiyoshi, Takayuki, Kwan, Edmond M, Ng, Sarah W S, Annala, Matti, Donnellan, Gráinne, Herberts, Cameron, Benoist, Guillemette E, Hamberg, Paul, Somford, Diederik M, van Oort, Inge M, Schalken, Jack A, Mehra, Niven, van Erp, Nielka P, Wyatt, Alexander W

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The 5-Hydroxymethylcytosine Landscape of Prostate Cancer von Sjöström, Martin, Zhao, Shuang G, Levy, Samuel, Zhang, Meng, Ning, Yuhong, Shrestha, Raunak, Lundberg, Arian, Herberts, Cameron, Foye, Adam, Aggarwal, Rahul, Hua, Junjie T, Li, Haolong, Bergamaschi, Anna, Maurice-Dror, Corinne, Maheshwari, Ashutosh, Chen, Sujun, Ng, Sarah W S, Ye, Wenbin, Petricca, Jessica, Fraser, Michael, Chesner, Lisa, Perry, Marc D, Moreno-Rodriguez, Thaidy, Chen, William S, Alumkal, Joshi J, Chou, Jonathan, Morgans, Alicia K, Beer, Tomasz M, Thomas, George V, Gleave, Martin, Lloyd, Paul, Phillips, Tierney, McCarthy, Erin, Haffner, Michael C, Zoubeidi, Amina, Annala, Matti, Reiter, Robert E, Rettig, Matthew B, Witte, Owen N, Fong, Lawrence, Bose, Rohit, Huang, Franklin W, Luo, Jianhua, Bjartell, Anders, Lang, Joshua M, Mahajan, Nupam P, Lara, Primo N, Evans, Christopher P, Tran, Phuoc T, Posadas, Edwin M, He, Chuan, Cui, Xiao-Long, Huang, Jiaoti, Zwart, Wilbert, Gilbert, Luke A, Maher, Christopher A, Boutros, Paul C, Chi, Kim N, Ashworth, Alan, Small, Eric J, He, Housheng H, Wyatt, Alexander W, Quigley, David A, Feng, Felix Y

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Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer von Fonseca, Nicolette M., Maurice-Dror, Corinne, Herberts, Cameron, Tu, Wilson, Fan, William, Murtha, Andrew J., Kollmannsberger, Catarina, Kwan, Edmond M., Parekh, Karan, Schönlau, Elena, Bernales, Cecily Q., Donnellan, Gráinne, Ng, Sarah W. S., Sumiyoshi, Takayuki, Vergidis, Joanna, Noonan, Krista, Finch, Daygen L., Zulfiqar, Muhammad, Miller, Stacy, Parimi, Sunil, Lavoie, Jean-Michel, Hardy, Edward, Soleimani, Maryam, Nappi, Lucia, Eigl, Bernhard J., Kollmannsberger, Christian, Taavitsainen, Sinja, Nykter, Matti, Tolmeijer, Sofie H., Boerrigter, Emmy, Mehra, Niven, van Erp, Nielka P., De Laere, Bram, Lindberg, Johan, Grönberg, Henrik, Khalaf, Daniel J., Annala, Matti, Chi, Kim N., Wyatt, Alexander W.

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Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping von Warner, Evan W, Van der Eecken, Kim, Murtha, Andrew J, Kwan, Edmond M, Herberts, Cameron, Sipola, Joonatan, Ng, Sarah W S, Chen, Xinyi E, Fonseca, Nicolette M, Ritch, Elie, Schönlau, Elena, Bernales, Cecily Q, Donnellan, Gráinne, Munzur, Aslı D, Parekh, Karan, Beja, Kevin, Wong, Amanda, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, De Laere, Bram, Annala, Matti, Vandekerkhove, Gillian, Ost, Piet, Wyatt, Alexander W

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Forecasting SARS-CoV-2 spike protein evolution from small data by deep learning and regression von King, Samuel, Chen, Xinyi E., Ng, Sarah W. S., Rostin, Kimia, Hahn, Samuel V., Roberts, Tylo, Schwab, Janella C., Sekhon, Parneet, Kagieva, Madina, Reilly, Taylor, Qi, Ruo Chen, Salman, Paarsa, Hong, Ryan J., Ma, Eric J., Hallam, Steven J.

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Abstract 41: Multi-focal genomic dissection of synchronous primary and metastatic tissue from de novo metastatic prostate cancer von Warner, Evan, Van der Eecken, Kim, Murtha, Andrew J., Kwan, Edmond M., Ng, Sarah W., Chen, Xinyi E., Bernales, Cecily Q., Donnellan, Grainne, Schonlau, Elena, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, Vandekerkhove, Gillian, Ritch, Elie, Annala, Matti, De Laere, Bram, Ost, Piet, Wyatt, Alexander W.

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Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing von Herberts, Cameron, Annala, Matti, Sipola, Joonatan, Ng, Sarah W., Chen, Xinyi E., Nurminen, Anssi, Korhonen, Olga, Munzur, Aslı D., Beja, Kevin, Schönlau, Elena, Bernales, Cecily Q., Ritch, Elie, Bacon, Jack V., Lack, Nathan A., Nykter, Matti, Aggarwal, Rahul, Small, Eric J., Gleave, Martin E., Quigley, David A., Feng, Felix Y., Chi, Kim N., Wyatt, Alexander W.

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Designing bioresponsive nanomaterials for intracellular self-assembly von Chagri, Sarah, Ng, David Y. W., Weil, Tanja

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Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity‐modulated radioth... von Pan, Jian Ji, Ng, Wai Tong, Zong, Jing Feng, Lee, Sarah W. M., Choi, Horace C. W., Chan, Lucy L. K., Lin, Shao Jun, Guo, Qiao Juan, Sze, Henry C. K., Chen, Yun Bin, Xiao, You Ping, Kan, Wai Kuen, O'Sullivan, Brian, Xu, Wei, Le, Quynh Thu, Glastonbury, Christine M., Colevas, A. Dimitrios, Weber, Randal S., Lydiatt, William, Shah, Jatin P., Lee, Anne W. M.

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Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore von Pratanwanich, Ploy N., Yao, Fei, Chen, Ying, Koh, Casslynn W. Q., Wan, Yuk Kei, Hendra, Christopher, Poon, Polly, Goh, Yeek Teck, Yap, Phoebe M. L., Chooi, Jing Yuan, Chng, Wee Joo, Ng, Sarah B., Thiery, Alexandre, Goh, W. S. Sho, Göke, Jonathan

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A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease von Burgner, David, Davila, Sonia, Breunis, Willemijn B, Ng, Sarah B, Li, Yi, Bonnard, Carine, Ling, Ling, Wright, Victoria J, Thalamuthu, Anbupalam, Odam, Miranda, Shimizu, Chisato, Burns, Jane C, Levin, Michael, Kuijpers, Taco W, Hibberd, Martin L

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Exome sequencing as a tool for Mendelian disease gene discovery von Bamshad, Michael J, Shendure, Jay, Ng, Sarah B, Bigham, Abigail W, Tabor, Holly K, Emond, Mary J, Nickerson, Deborah A

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Convergent somatic mutations in metabolism genes in chronic liver disease von Ng, Stanley W. K., Rouhani, Foad J., Brunner, Simon F., Brzozowska, Natalia, Aitken, Sarah J., Yang, Ming, Abascal, Federico, Moore, Luiza, Nikitopoulou, Efterpi, Chappell, Lia, Leongamornlert, Daniel, Ivovic, Aleksandra, Robinson, Philip, Butler, Timothy, Sanders, Mathijs A., Williams, Nicholas, Coorens, Tim H. H., Teague, Jon, Raine, Keiran, Butler, Adam P., Hooks, Yvette, Wilson, Beverley, Birtchnell, Natalie, Naylor, Huw, Davies, Susan E., Stratton, Michael R., Martincorena, Iñigo, Rahbari, Raheleh, Frezza, Christian, Hoare, Matthew, Campbell, Peter J.

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Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumour dissemination von Sundar, Raghav, Liu, Drolaiz HW, Hutchins, Gordon GA, Slaney, Hayley L, Silva, Arnaldo NS, Oosting, Jan, Hayden, Jeremy D, Hewitt, Lindsay C, Ng, Cedric CY, Mangalvedhekar, Amrita, Ng, Sarah B, Tan, Iain BH, Tan, Patrick, Grabsch, Heike I

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Targeted capture and massively parallel sequencing of 12 human exomes von Ng, Sarah B, Shendure, Jay, Turner, Emily H, Robertson, Peggy D, Flygare, Steven D, Bigham, Abigail W, Lee, Choli, Shaffer, Tristan, Wong, Michelle, Bhattacharjee, Arindam, Eichler, Evan E, Bamshad, Michael, Nickerson, Deborah A

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An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations von Boumelha, Jesse, de Carné Trécesson, Sophie, Law, Emily K, Romero-Clavijo, Pablo, Coelho, Matthew A, Ng, Kevin W, Mugarza, Edurne, Moore, Christopher, Rana, Sareena, Caswell, Deborah R, Murillo, Miguel, Hancock, David C, Argyris, Prokopios P, Brown, William L, Durfee, Cameron, Larson, Lindsay K, Vogel, Rachel I, Suárez-Bonnet, Alejandro, Priestnall, Simon L, East, Philip, Ross, Sarah J, Kassiotis, George, Molina-Arcas, Miriam, Swanton, Charles, Harris, Reuben, Downward, Julian

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Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials von Baigent, Colin, Emberson, JonathanR, Haynes, Richard, Herrington, William G., Judge, Parminder, Landray, Martin J., Mayne, Kaitlin J., Ng, Sarah Y.A., Preiss, David, Roddick, Alistair J., Staplin, Natalie, Zhu, Doreen, Anker, Stefan D., Bhatt, Deepak L., Brueckmann, Martina, Butler, Javed, Cherney, David Z.I., Green, Jennifer B., Hauske, Sibylle J., Heerspink, Hiddo J.L., Inzucchi, Silvio E., Jardine, Meg J., Liu, Chih-Chin, Mahaffey, Kenneth W., McCausland, Finnian R., McGuire, Darren K., McMurray, John J.V., Neal, Bruce, Neuen, Brendon L., Packer, Milton, Perkovic, Vlado, Sabatine, Marc S., Solomon, Scott D., Vaduganathan, Muthiah, Wanner, Christoph, Wheeler, David C., Wiviott, Stephen D., Zannad, Faiez

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