Comparison of human B cell activation by TLR7 and TLR9 agonists von Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, Birmachu, Woubalem

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Purified B cells were cultured for 10 days in the presence of the indicated concentrations of an IRM or CpG2006 von Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Sefik S Alkan, Woubalem Birmachu

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Purified B cells were stimulated with the indicated IRM or with CpG2006 von Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Sefik S Alkan, Woubalem Birmachu

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Purified B cells from 3 different donors were stimulated with the indicated IRM or with CpG2006 for 2, 8 or 24 hours, and then were harvested for mRNA analysis von Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Sefik S Alkan, Woubalem Birmachu

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Highly purified B cells from 3 different donors were examined for expression of the TLRs by RT-PCR von Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Sefik S Alkan, Woubalem Birmachu

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