Improved vectors and genome-wide libraries for CRISPR screening von Sanjana, Neville E, Shalem, Ophir, Zhang, Feng

Volltext

High-throughput functional genomics using CRISPR–Cas9 von Shalem, Ophir, Sanjana, Neville E., Zhang, Feng

Volltext

Genome-scale CRISPR pooled screens von Sanjana, Neville E.

Volltext

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening von Joung, Julia, Konermann, Silvana, Gootenberg, Jonathan S, Abudayyeh, Omar O, Platt, Randall J, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng

Volltext

CRISPR in cancer biology and therapy von Katti, Alyna, Diaz, Bianca J., Caragine, Christina M., Sanjana, Neville E., Dow, Lukas E.

Volltext

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites von Schwartz, Schraga, Mumbach, Maxwell R., Jovanovic, Marko, Wang, Tim, Maciag, Karolina, Bushkin, G. Guy, Mertins, Philipp, Ter-Ovanesyan, Dmitry, Habib, Naomi, Cacchiarelli, Davide, Sanjana, Neville E., Freinkman, Elizaveta, Pacold, Michael E., Satija, Rahul, Mikkelsen, Tarjei S., Hacohen, Nir, Zhang, Feng, Carr, Steven A., Lander, Eric S., Regev, Aviv

Volltext

Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens von Guo, Xinyi, Rahman, Jahan A., Wessels, Hans-Hermann, Méndez-Mancilla, Alejandro, Haro, Daniel, Chen, Xinru, Sanjana, Neville E.

Volltext

Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells von Daniloski, Zharko, Jordan, Tristan X., Wessels, Hans-Hermann, Hoagland, Daisy A., Kasela, Silva, Legut, Mateusz, Maniatis, Silas, Mimitou, Eleni P., Lu, Lu, Geller, Evan, Danziger, Oded, Rosenberg, Brad R., Phatnani, Hemali, Smibert, Peter, Lappalainen, Tuuli, tenOever, Benjamin R., Sanjana, Neville E.

Volltext

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells von Shalem, Ophir, Sanjana, Neville E., Hartenian, Ella, Shi, Xi, Scott, David A., Mikkelsen, Tarjei S., Heckl, Dirk, Ebert, Benjamin L., Root, David E., Doench, John G., Zhang, Feng

Volltext

High-resolution interrogation of functional elements in the noncoding genome von Sanjana, Neville E., Wright, Jason, Zheng, Kaijie, Shalem, Ophir, Fontanillas, Pierre, Joung, Julia, Cheng, Christine, Regev, Aviv, Zhang, Feng

Volltext

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis von Chen, Sidi, Sanjana, Neville E., Zheng, Kaijie, Shalem, Ophir, Lee, Kyungheon, Shi, Xi, Scott, David A., Song, Jun, Pan, Jen Q., Weissleder, Ralph, Lee, Hakho, Zhang, Feng, Sharp, Phillip A.

Volltext

Voices of the new generation: open science is good for science (and for you) von Sanjana, Neville E.

Volltext

Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells von Mimitou, Eleni P., Cheng, Anthony, Montalbano, Antonino, Hao, Stephanie, Stoeckius, Marlon, Legut, Mateusz, Roush, Timothy, Herrera, Alberto, Papalexi, Efthymia, Ouyang, Zhengqing, Satija, Rahul, Sanjana, Neville E., Koralov, Sergei B., Smibert, Peter

Volltext

A transcription activator-like effector toolbox for genome engineering von Sanjana, Neville E, Cong, Le, Zhou, Yang, Cunniff, Margaret M, Feng, Guoping, Zhang, Feng

Volltext

Identification of essential genes for cancer immunotherapy von Patel, Shashank J., Sanjana, Neville E., Kishton, Rigel J., Eidizadeh, Arash, Vodnala, Suman K., Cam, Maggie, Gartner, Jared J., Jia, Li, Steinberg, Seth M., Yamamoto, Tori N., Merchant, Anand S., Mehta, Gautam U., Chichura, Anna, Shalem, Ophir, Tran, Eric, Eil, Robert, Sukumar, Madhusudhanan, Guijarro, Eva Perez, Day, Chi-Ping, Robbins, Paul, Feldman, Steve, Merlino, Glenn, Zhang, Feng, Restifo, Nicholas P.

Volltext

Hypoxia as a therapy for mitochondrial disease von Jain, Isha H., Zazzeron, Luca, Goli, Rahul, Alexa, Kristen, Schatzman-Bone, Stephanie, Dhillon, Harveen, Goldberger, Olga, Peng, Jun, Shalem, Ophir, Sanjana, Neville E., Zhang, Feng, Goessling, Wolfram, Zapol, Warren M., Mootha, Vamsi K.

Volltext

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis von Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E.

Volltext

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks von Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M., Herbst, Rebecca H., Dixit, Atray, Ye, Chun Jimmie, Przybylski, Dariusz, Platt, Randall J., Tirosh, Itay, Sanjana, Neville E., Shalem, Ophir, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A., Zhang, Feng, Hacohen, Nir, Regev, Aviv

Volltext

The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types von Daniloski, Zharko, Jordan, Tristan X., Ilmain, Juliana K., Guo, Xinyi, Bhabha, Gira, TenOever, Benjamin R., Sanjana, Neville E.

Volltext

Massively parallel Cas13 screens reveal principles for guide RNA design von Wessels, Hans-Hermann, Méndez-Mancilla, Alejandro, Guo, Xinyi, Legut, Mateusz, Daniloski, Zharko, Sanjana, Neville E.

Volltext