Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse von Ercilla, Amaia, Feu, Sonia, Aranda, Sergi, Llopis, Alba, Brynjólfsdóttir, Sólveig Hlín, Sørensen, Claus Storgaard, Toledo, Luis Ignacio, Agell, Neus

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RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress von Feu, Sonia, Unzueta, Fernando, Ercilla, Amaia, Pérez-Venteo, Alejandro, Jaumot, Montserrat, Agell, Neus

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Modeling and subtleties of K-Ras and Calmodulin interaction von Garrido, Eduardo, Lázaro, Juan, Jaumot, Montserrat, Agell, Neus, Rubio-Martinez, Jaime

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Near‐tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness von Wangsa, Darawalee, Quintanilla, Isabel, Torabi, Keyvan, Vila‐Casadesús, Maria, Ercilla, Amaia, Klus, Gregory, Yuce, Zeynep, Galofré, Claudia, Cuatrecasas, Miriam, José Lozano, Juan, Agell, Neus, Cimini, Daniela, Castells, Antoni, Ried, Thomas, Camps, Jordi

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KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer von Cabot, Débora, Brun, Sònia, Paco, Noelia, Ginesta, Mireia M., Gendrau-Sanclemente, Núria, Abuasaker, Baraa, Ruiz-Fariña, Triana, Barceló, Carles, Cuatrecasas, Miriam, Bosch, Marta, Rentero, Carles, Pons, Gabriel, Estanyol, Josep M., Capellà, Gabriel, Jaumot, Montserrat, Agell, Neus

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Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth von BARCELO, Carles, PACO, Noelia, MORELL, Mireia, ALVAREZ-MOYA, Blanca, BOTA-RABASSEDAS, Neus, JAUMOT, Montserrat, VILARDELL, Felip, CAPELLA, Gabriel, AGELL, Neus

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Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds von Pallara, Chiara, Cabot, Debora, Rivas, Josep, Brun, Sonia, Seco, Jesús, Abuasaker, Baraa, Tarragó, Teresa, Jaumot, Montserrat, Prades, Roger, Agell, Neus

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clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes von Lu, Albert, Tebar, Francesc, Alvarez-Moya, Blanca, López-Alcalá, Cristina, Calvo, Maria, Enrich, Carlos, Agell, Neus, Nakamura, Takeshi, Matsuda, Michiyuki, Bachs, Oriol

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Modulation of the Ras/Raf/MEK/ERK pathway by Ca2+, and Calmodulin von Agell, Neus, Bachs, Oriol, Rocamora, Nati, Villalonga, Priam

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SUMO regulates p21Cip1 intracellular distribution and with p21Cip1 facilitates multiprotein complex formation in the nucleolus upon DNA damage von Brun, Sonia, Abella, Neus, Berciano, Maria T, Tapia, Olga, Jaumot, Montserrat, Freire, Raimundo, Lafarga, Miguel, Agell, Neus

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p21 as a transcriptional co-repressor of S-phase and mitotic control genes von Ferrándiz, Nuria, Caraballo, Juan M, García-Gutierrez, Lucía, Devgan, Vikram, Rodriguez-Paredes, Manuel, Lafita, M Carmen, Bretones, Gabriel, Quintanilla, Andrea, Muñoz-Alonso, M Jose, Blanco, Rosa, Reyes, Jose C, Agell, Neus, Delgado, M Dolores, Dotto, G Paolo, León, Javier

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Proteasome Inhibition Reduces Proliferation, Collagen Expression, and Inflammatory Cytokine Production in Nasal Mucosa and Polyp Fibroblasts von Pujols, Laura, Fernández-Bertolín, Laura, Fuentes-Prado, Mireya, Alobid, Isam, Roca-Ferrer, Jordi, Agell, Neus, Mullol, Joaquim, Picado, César

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The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest von Llopis, Alba, Salvador, Noelia, Ercilla, Amaia, Guaita-Esteruelas, Sandra, Barrantes, Ivan del Barco, Gupta, Jalaj, Gaestel, Matthias, Davis, Roger J., Nebreda, Angel R., Agell, Neus

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Identification of Essential Interacting Elements in K-Ras/Calmodulin Binding and Its Role in K-Ras Localization von Lopez-Alcalá, Cristina, Alvarez-Moya, Blanca, Villalonga, Priam, Calvo, Maria, Bachs, Oriol, Agell, Neus

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Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells von Barceló, Carles, Etchin, Julia, Mansour, Marc R, Sanda, Takaomi, Ginesta, Mireia M, Sanchez-Arévalo Lobo, Victor J, Real, Francisco X, Capellà, Gabriel, Estanyol, Josep M, Jaumot, Montserrat, Look, A. Thomas, Agell, Neus

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New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress von Ercilla, Amaia, Llopis, Alba, Feu, Sonia, Aranda, Sergi, Ernfors, Patrik, Freire, Raimundo, Agell, Neus

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Calmodulin Binds to K-Ras, but Not to H- or N-Ras, and Modulates Its Downstream Signaling von Villalonga, Priam, López-Alcalá, Cristina, Bosch, Marta, Chiloeches, Antonio, Rocamora, Nativitat, Gil, Joan, Marais, Richard, Marshall, Christopher J., Bachs, Oriol, Agell, Neus

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The SET Protein Regulates G2/M Transition by Modulating Cyclin B-Cyclin-dependent Kinase 1 Activity von Canela, Núria, Rodriguez-Vilarrupla, Aina, Estanyol, Josep Marı́a, Dı́az, Carmen, Pujol, Maria Jesús, Agell, Neus, Bachs, Oriol

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Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status von Barceló, Carles, Paco, Noelia, Beckett, Alison J, Alvarez-Moya, Blanca, Garrido, Eduard, Gelabert, Mariona, Tebar, Francesc, Jaumot, Montserrat, Prior, Ian, Agell, Neus

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Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway von Tebar, Francesc, Villalonga, Priam, Sorkina, Tatiana, Agell, Neus, Sorkin, Alexander, Enrich, Carlos

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