First‐in‐human assessment of PRX002, an anti–α‐synuclein monoclonal antibody, in healthy volunteers von Schenk, Dale B., Koller, Martin, Ness, Daniel K., Griffith, Sue G., Grundman, Michael, Zago, Wagner, Soto, Jay, Atiee, George, Ostrowitzki, Susanne, Kinney, Gene G.

Volltext

First-in-human assessment of PRX002, an anti-[alpha]-synuclein monoclonal antibody, in healthy volunteers von Schenk, Dale B, Koller, Martin, Ness, Daniel K, Griffith, Sue G, Grundman, Michael, Zago, Wagner, Soto, Jay, Atiee, George, Ostrowitzki, Susanne, Kinney, Gene G

Volltext

Plasma Actuator Blade Tip Clearance Flow Control in a Linear Turbine Cascade von Van Ness, Daniel K, Corke, Thomas C, Morris, Scott C

Volltext

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity von Müller, Lutz, Mauthe, Robert J., Riley, Christopher M., Andino, Marta M., Antonis, David De, Beels, Chris, DeGeorge, Joseph, De Knaep, Alfons G.M., Ellison, Dean, Fagerland, Jane A., Frank, Rebecca, Fritschel, Betsy, Galloway, Sheila, Harpur, Ernie, Humfrey, Charles D.N., Jacks, Alexander S., Jagota, Nirdosh, Mackinnon, John, Mohan, Ganapathy, Ness, Daniel K., O’Donovan, Michael R., Smith, Mark D., Vudathala, Gopi, Yotti, Larry

Volltext

Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance von Bercu, Joel P., Hoffman, Wherly P., Lee, Cindy, Ness, Daniel K.

Volltext

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposit... von Racke, Margaret M, Boone, Laura I, Hepburn, Deena L, Parsadainian, Maia, Bryan, Matthew T, Ness, Daniel K, Piroozi, Kathy S, Jordan, William H, Brown, Donna D, Hoffman, Wherly P, Holtzman, David M, Bales, Kelly R, Gitter, Bruce D, May, Patrick C, Paul, Steven M, DeMattos, Ronald B

Volltext

Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti–α-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease: A Randomized Clinical Trial von Jankovic, Joseph, Goodman, Ira, Safirstein, Beth, Marmon, Tonya K, Schenk, Dale B, Koller, Martin, Zago, Wagner, Ness, Daniel K, Griffith, Sue G, Grundman, Michael, Soto, Jay, Ostrowitzki, Susanne, Boess, Frank G, Martin-Facklam, Meret, Quinn, Joseph F, Isaacson, Stuart H, Omidvar, Omid, Ellenbogen, Aaron, Kinney, Gene G

Volltext

Discovery of (R)‑4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro‑1H‑pyrazolo[4,3‑c]quinoline (ELND006) and (R)‑4-Cyclopropyl-8-fluoro-5-(6-(trifluorome... von Probst, Gary, Aubele, Danielle L, Bowers, Simeon, Dressen, Darren, Garofalo, Albert W, Hom, Roy K, Konradi, Andrei W, Marugg, Jennifer L, Mattson, Matthew N, Neitzel, Martin L, Semko, Chris M, Sham, Hing L, Smith, Jenifer, Sun, Minghua, Truong, Anh P, Ye, Xiaocong M, Xu, Ying-zi, Dappen, Michael S, Jagodzinski, Jacek J, Keim, Pamela S, Peterson, Brian, Latimer, Lee H, Quincy, David, Wu, Jing, Goldbach, Erich, Ness, Daniel K, Quinn, Kevin P, Sauer, John-Michael, Wong, Karina, Zhang, Hongbin, Zmolek, Wes, Brigham, Elizabeth F, Kholodenko, Dora, Hu, Kang, Kwong, Grace T, Lee, Michael, Liao, Anna, Motter, Ruth N, Sacayon, Patricia, Santiago, Pamela, Willits, Christopher, Bard, Frédérique, Bova, Michael P, Hemphill, Susanna S, Nguyen, Lam, Ruslim, Lany, Tanaka, Kevin, Tanaka, Pearl, Wallace, William, Yednock, Ted A, Basi, Guriqbal S

Volltext

Analysis of Rodent Growth Data in Toxicology Studies von Hoffman, Wherly P., Ness, Daniel K., van Lier, Robert B. L.

Volltext

P1-017: Comparison of cisternal and lumbar cerebrospinal fluid amyloid-beta concentrations following oral administration of LY450139 dihydrate to Beagle dogs von Cocke, Patrick J, Boggs, Leonard N, Ness, Daniel K, May, Patrick C

Volltext

Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat von Ness, Daniel K., Schantz, Susan L., Moshtaghian, Jamal, Hansen, Larry G.

Volltext

First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers: Immunotherapy for Parkinson's Disease von Schenk, Dale B., Koller, Martin, Ness, Daniel K., Griffith, Sue G., Grundman, Michael, Zago, Wagner, Soto, Jay, Atiee, George, Ostrowitzki, Susanne, Kinney, Gene G.

Volltext

CHARACTERIZATION OF FUMONISIN TOXICITY IN ORALLY AND INTRAVENOUSLY DOSED SWINE von HASCHEK, WM, MOTELIN, G, NESS, DK, HARLIN, KS, HALL, WF, VESONDER, RF, PETERSON, RE, BEASLEY, VR

Volltext

Discovery of ( R )-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1 H -pyrazolo[4,3- c ]quinoline (ELND006) and ( R )-4-Cyclopropyl-8-fluoro-5-(6-(tri... von Probst, Gary, Aubele, Danielle L., Bowers, Simeon, Dressen, Darren, Garofalo, Albert W., Hom, Roy K., Konradi, Andrei W., Marugg, Jennifer L., Mattson, Matthew N., Neitzel, Martin L., Semko, Chris M., Sham, Hing L., Smith, Jenifer, Sun, Minghua, Truong, Anh P., Ye, Xiaocong M., Xu, Ying-zi, Dappen, Michael S., Jagodzinski, Jacek J., Keim, Pamela S., Peterson, Brian, Latimer, Lee H., Quincy, David, Wu, Jing, Goldbach, Erich, Ness, Daniel K., Quinn, Kevin P., Sauer, John-Michael, Wong, Karina, Zhang, Hongbin, Zmolek, Wes, Brigham, Elizabeth F., Kholodenko, Dora, Hu, Kang, Kwong, Grace T., Lee, Michael, Liao, Anna, Motter, Ruth N., Sacayon, Patricia, Santiago, Pamela, Willits, Christopher, Bard, Frédérique, Bova, Michael P., Hemphill, Susanna S., Nguyen, Lam, Ruslim, Lany, Tanaka, Kevin, Tanaka, Pearl, Wallace, William, Yednock, Ted A., Basi, Guriqbal S.

Volltext

Spatial Learning Deficits in Adult Rats Exposed to ortho-Substituted PCB Congeners during Gestation and Lactation von SCHANTZ, SUSAN L., MOSHTAGHIAN, JAMAL, NESS, DANIEL K.

Volltext

ACOUSTIC LINER WITH NON-UNIFORM VOLUMETRIC DISTRIBUTION von TOPOL, David A, BIFULCO, Anthony R, KNAUL, David A, VAN NESS, Daniel K, LAFAVOR, Michael Raymond

Volltext bestellen

GAS TURBINE ENGINES WITH HEATED CASES von CLARKSON, Steven, VAN NESS, Daniel K, REMBISH, Paul Thomas

Volltext bestellen

P2-053 Reduced β-amyloid burden, increased C-99 concentrations and evaluation of neuropathology in the brains of PDAPP mice given LY450139 dihydrate daily by gavage for 5 months von Ness, Daniel K., Boggs, Leonard N., Hepburn, Deena L., Gitter, Bruce, Long, Gerald G., May, Patrick C., Piroozi, Kathy S., Schafer, Kenneth A., Yang, Zhixiang

Volltext

Acoustic liner with non-uniform volumetric distribution von Topol, David A, Knaul, David A, LaFavor, Michael Raymond, Bifulco, Anthony R, Van Ness, Daniel K

Volltext bestellen

ACOUSTIC LINER WITH NON-UNIFORM VOLUMETRIC DISTRIBUTION von Topol, David A, Knaul, David A, LaFavor, Michael Raymond, Bifulco, Anthony R, Van Ness, Daniel K

Volltext bestellen