Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis von Bryce, Paul J., PhD, Falahati, Rustom, PhD, Kenney, Laurie L., PhD, Leung, John, BS, Bebbington, Christopher, PhD, Tomasevic, Nenad, PhD, Krier, Rebecca A., MS, Hsu, Chia-Lin, PhD, Shultz, Leonard D., PhD, Greiner, Dale L., PhD, Brehm, Michael A., PhD

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A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation von Schanin, Julia, Gebremeskel, Simon, Korver, Wouter, Falahati, Rustom, Butuci, Melina, Haw, Tatt Jhong, Nair, Prema M., Liu, Gang, Hansbro, Nicole G., Hansbro, Philip M., Evensen, Erik, Brock, Emily C., Xu, Alan, Wong, Alan, Leung, John, Bebbington, Christopher, Tomasevic, Nenad, Youngblood, Bradford A.

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Src phosphorylation of cortactin enhances actin assembly von Tehrani, Shandiz, Tomasevic, Nenad, Weed, Scott, Sakowicz, Roman, Cooper, John A

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R-Spondin family members regulate the Wnt pathway by a common mechanism von Kim, Kyung-Ah, Wagle, Marie, Tran, Karolyn, Zhan, Xiaoming, Dixon, Melissa A, Liu, Shouchun, Gros, Delphine, Korver, Wouter, Yonkovich, Shirlee, Tomasevic, Nenad, Binnerts, Minke, Abo, Arie

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Discovery, Function, and Therapeutic Targeting of Siglec-8 von Youngblood, Bradford A, Leung, John, Falahati, Rustom, Williams, Jason, Schanin, Julia, Brock, Emily C, Singh, Bhupinder, Chang, Alan T, O'Sullivan, Jeremy A, Schleimer, Robert P, Tomasevic, Nenad, Bebbington, Christopher R, Bochner, Bruce S

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The eosinophil surface receptor epidermal growth factor–like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders von Legrand, Fanny, PhD, PharmD, Tomasevic, Nenad, PhD, Simakova, Olga, PhD, Lee, Chyi-Chia Richard, MD, PhD, Wang, Zengfang, PhD, Raffeld, Mark, MD, Makiya, Michelle A., MS, Palath, Varghese, PhD, Leung, John, BS, Baer, Mark, PhD, Yarranton, Geoffrey, PhD, Maric, Irina, MD, Bebbington, Christopher, PhD, Klion, Amy D., MD

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R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 von Binnerts, Minke E, Kim, Kyung-Ah, Bright, Jessica M, Patel, Sejal M, Tran, Karolyn, Zhou, Mei, Leung, John M, Liu, Yi, Lomas, Woodrow E. III, Dixon, Melissa, Hazell, Sophie A, Wagle, Marie, Nie, Wen-Sheng, Tomasevic, Nenad, Williams, Jason, Zhan, Xiaoming, Levy, Michael D, Funk, Walter D, Abo, Arie

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Differential Regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2 von Tomasevic, Nenad, Jia, Zhiheng, Russell, Alan, Fujii, Toby, Hartman, James J, Clancy, Sheila, Wang, Manping, Beraud, Christophe, Wood, Kenneth W, Sakowicz, Roman

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FAK promotes organization of fibronectin matrix and fibrillar adhesions von Ilić, Dusko, Kovacic, Branka, Johkura, Kohei, Schlaepfer, David D, Tomasević, Nenad, Han, Qin, Kim, Jae-Beom, Howerton, Kyle, Baumbusch, Clark, Ogiwara, Naoko, Streblow, Daniel N, Nelson, Jay A, Dazin, Paul, Shino, Yuji, Sasaki, Katsunori, Damsky, Caroline H

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Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis von Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bochner, Bruce S., Rasmussen, Henrik S., Peterson, Kathryn, Bebbington, Christopher, Tomasevic, Nenad

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Human EMR1, An Eosinophil-Specific Surface Receptor Of Unknown Function, Is Modulated In Vivo and In Vitro von Legrand, Fanny, Dr, Tomasevic, Nenad, Dr, Makiya, Michelle, Mrs, Bebbington, Christopher, Dr, Klion, Amy D., Dr

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Atopic Dermatitis Skin Biopsies Have High Numbers of Activated Mast Cells that Are Inhibited by AK002 after Stimulation Ex Vivo von Youngblood, Brad, Schanin, Julia, Tomasevic, Nenad, Kamboj, Amol

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AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast... von Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bryce, Paul J., Bright, Jessica, Williams, Jason, Shultz, Leonard D., Greiner, Dale L., Brehm, Michael A., Bebbington, Christopher, Tomasevic, Nenad

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Sialic acid–binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies von Legrand, Fanny, Cao, Yun, Wechsler, Joshua B., Zhu, Xiang, Zimmermann, Nives, Rampertaap, Shakuntala, Monsale, Joseph, Romito, Kimberly, Youngblood, Bradford A., Brock, Emily C., Makiya, Michelle A., Tomasevic, Nenad, Bebbington, Christopher, Maric, Irina, Metcalfe, Dean D., Bochner, Bruce S., Klion, Amy D.

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Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis von Youngblood, Bradford A., Brock, Emily C., Leung, John, Falahati, Rustom, Bochner, Bruce S., Rasmussen, Henrik S., Peterson, Kathryn, Bebbington, Christopher, Tomasevic, Nenad

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AK002, a Novel Humanized Monoclonal Antibody to Siglec-8, Inhibits Mast Cell Activity and Depletes Eosinophils in Ex Vivo Bone Marrow Tissue from Patients with Systemic Mastocytosi... von Youngblood, Bradford A, Brock, Emily C, Leung, John, Chang, Alan T, Bebbington, Christopher, Tomasevic, Nenad

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DR-01, a Non-Fucosylated Anti-CD94 Antibody, Depletes Leukemic Cells in Ex Vivo and In Vivo Models of Large Granular Lymphocyte Leukemia von Shi, Kelly, Tan, Cindy, Bai, Lu, Richardson, Jennifer, Deng, Andy, Will, Matthias, Brehm, Michael, Greiner, Dale, Shultz, Leonard, Teramo, Antonella, Zambello, Renato, Feith, David J, Loughran, Thomas P., Tomasevic, Nenad

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352 - AK002, a First-in-Class, Humanized, Non-Fucosylated IGG1 Siglec-8 Antibody, Selectively Depletes Blood and Tissue Eosinophils von Youngblood, Bradford, Brock, Emily C., Leung, John, Bebbington, Christopher, Tomasevic, Nenad

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353 - Anti-Siglec-8 Antibody Reduces Eosinophil and Mast Cell Infiltration in a Mouse Model of Eosinophilic Gastritis: A Novel Therapeutic Approach for Eosinophilic Gastrointestina... von Youngblood, Bradford, Brock, Emily C., Leung, John, Bebbington, Christopher, Tomasevic, Nenad

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Identification of a U8 snoRNA-specific Binding Protein von Tomasevic, N, Peculis, B

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