Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels von Nemecz, Ákos, Prevost, Marie S., Menny, Anaïs, Corringer, Pierre-Jean

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Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation von Sauguet, Ludovic, Shahsavar, Azadeh, Poitevin, Frédéric, Huon, Christèle, Menny, Anaïs, Nemecz, Àkos, Haouz, Ahmed, Changeux, Jean-Pierre, Corringer, Pierre-Jean, Delarue, Marc

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Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion c... von Nemecz, Ákos, Hu, Haidai, Fourati, Zaineb, Van Renterghem, Catherine, Delarue, Marc, Corringer, Pierre-Jean

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Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template von Grimster, Neil P., Stump, Bernhard, Fotsing, Joseph R., Weide, Timo, Talley, Todd T., Yamauchi, John G., Nemecz, Ákos, Kim, Choel, Ho, Kwok-Yiu, Sharpless, K. Barry, Taylor, Palmer, Fokin, Valery V.

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Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor von Li, Qimeng, Nemecz, Ákos, Aymé, Gabriel, Dejean de la Bâtie, Gabrielle, Prevost, Marie S., Pons, Stéphanie, Barilone, Nathalie, Baachaoui, Rayen, Maskos, Uwe, Lafaye, Pierre, Corringer, Pierre-Jean

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VHH Nanobody Versatility against Pentameric Ligand-Gated Ion Channels von Nemecz, Dorota, Nowak, Weronika A., Nemecz, Ákos

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Short‐chain mono‐carboxylates as negative modulators of allosteric transitions in Gloeobacter violaceus ligand‐gated ion channel, and impact of a pre‐β5 strand (Loop Ω) double muta... von Van Renterghem, Catherine, Nemecz, Ákos, Medjebeur, Karima, Corringer, Pierre‐Jean

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Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca++ Sensors von Yamauchi, John G., Nemecz, Ákos, Nguyen, Quoc Thang, Muller, Arnaud, Schroeder, Lee F., Talley, Todd T., Lindstrom, Jon, Kleinfeld, David, Taylor, Palmer

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The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor von Rojsanga, Piyanuch, Boonyarat, Chantana, Utsintong, Maleeruk, Nemecz, Ákos, Yamauchi, John G., Talley, Todd T., Olson, Arthur J., Matsumoto, Kinzo, Vajragupta, Opa

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Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates von Yamauchi, John G, Gomez, Kimberly, Grimster, Neil, Dufouil, Mikael, Nemecz, Akos, Fotsing, Joseph R, Ho, Kwok-Yiu, Talley, Todd T, Sharpless, K Barry, Fokin, Valery V, Taylor, Palmer

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Fumarate as positive modulator of allosteric transitions in the pentameric ligand‐gated ion channel GLIC: requirement of an intact vestibular pocket von Van Renterghem, Catherine, Nemecz, Ákos, Delarue‐Cochin, Sandrine, Joseph, Delphine, Corringer, Pierre‐Jean

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Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation von Hu, Haidai, Nemecz, Ákos, Van Renterghem, Catherine, Fourati, Zaineb, Sauguet, Ludovic, Corringer, Pierre-Jean, Delarue, Marc

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Creating an α7 nicotinic acetylcholine recognition domain from the acetylcholine-binding protein: crystallographic and ligand selectivity analyses von Nemecz, Ákos, Taylor, Palmer

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Uncommon Features of a Novel γ-Proteobacterial Pentameric Ligand-Gated Ion Channel Revealed by its Crystal Structure von Hu, HaiDai, Nemecz, Akos, Fourati, Zeineb, Corringer, Pierre-Jean, Delarue, Marc

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Derivatives of 1,2,3‐triazole lead found to be selective and potent agonists at the α7 nicotinic acetylcholine receptor (1059.8) von Chen, Bill, Arunrungvichian, Kuntarat, Taylor, Palmer, Vajragupta, Opa, Fokin, Valery, Yamauchi, John, Nemecz, Akos

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The role of the β9–10 linker in nicotinic acetylcholine receptor selectivity von Nemecz, Akos, Ho, Kwok-yiu, Talley, Todd, Taylor, Palmer

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Structure‐activity Relationships of Bicyclic Amine Heterocycles with α7 Nicotinic Acetylcholine Receptors (nAChR) and Related Ligand‐gated Ion Channels von Gomez, Kimberly, Yamauchi, John G., Nemecz, Akos, Ho, Kwok‐Yiu, Talley, Todd T., Taylor, Palmer

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Fumarate as positive modulator of allosteric transitions in the pentameric ligand-gated ion channel GLIC: Requirement of an intact vestibular pocket: Fumarate as positive allosteri... von van Renterghem, Catherine, Nemecz, Ákos, Delarue-Cochin, Sandrine, Joseph, Delphine, Corringer, Pierre‐Jean

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X-Ray Structures of the Open and Resting Forms of the Same Bacterial Pentameric Ligand-Gated Ion Channel von Sauguet, Ludovic, Shahsavar, Azadeh, Poitevin, Frederic, Huon, Christele, Menny, Anais, Nemecz, Akos, Haouz, Ahmed, Changeux, Jean-Pierre, Corringer, Pierre-Jean, Delarue, Marc

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Structural Basis for Allosteric Transitions in the GLIC Pentameric Proton-Gated Ion Channel von Sauguet, Ludovic, Shahsavar, Azadeh, Poitevin, Frederic, Huon, Christele, Menny, Anais, nemecz, akos, Haouz, Ahmed, Changeux, Jean-Pierre, Corringer, Pierre-Jean, Delarue, Marc

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