Molecular States Underlying Androgen Receptor Activation: A Framework for Therapeutics Targeting Androgen Signaling in Prostate Cancer von NELSON, Peter S

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A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer von Chang, Kai-Hsiung, Li, Rui, Kuri, Barbara, Lotan, Yair, Roehrborn, Claus G., Liu, Jiayan, Vessella, Robert, Nelson, Peter S., Kapur, Payal, Guo, Xiaofeng, Mirzaei, Hamid, Auchus, Richard J., Sharifi, Nima

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TMPRSS2 and COVID-19: serendipity or Opportunity for Intervention? von Stopsack, Konrad H., Mucci, Lorelei A., Antonarakis, Emmanuel S., Nelson, Peter S., Kantoff, Philip W.

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Biallelic Inactivation of BRCA2 in Platinum-sensitive Metastatic Castration-resistant Prostate Cancer von Cheng, Heather H, Pritchard, Colin C, Boyd, Thomas, Nelson, Peter S, Montgomery, Bruce

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Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts von Bertram, Stephanie, Heurich, Adeline, Lavender, Hayley, Gierer, Stefanie, Danisch, Simon, Perin, Paula, Lucas, Jared M, Nelson, Peter S, Pöhlmann, Stefan, Soilleux, Elizabeth J

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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling von Brady, Lauren, Kriner, Michelle, Coleman, Ilsa, Morrissey, Colm, Roudier, Martine, True, Lawrence D., Gulati, Roman, Plymate, Stephen R., Zhou, Zoey, Birditt, Brian, Meredith, Rhonda, Geiss, Gary, Hoang, Margaret, Beechem, Joseph, Nelson, Peter S.

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Mismatch repair deficiency in metastatic prostate cancer: Response to PD-1 blockade and standard therapies von Graham, Laura S., Montgomery, Bruce, Cheng, Heather H., Yu, Evan Y., Nelson, Peter S., Pritchard, Colin, Erickson, Stephanie, Alva, Ajjai, Schweizer, Michael T.

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Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1 von Cai, Changmeng, He, Housheng Hansen, Chen, Sen, Coleman, Ilsa, Wang, Hongyun, Fang, Zi, Chen, Shaoyong, Nelson, Peter S., Liu, X. Shirley, Brown, Myles, Balk, Steven P.

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Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer von Wu, Yi-Mi, Cieślik, Marcin, Lonigro, Robert J., Vats, Pankaj, Reimers, Melissa A., Cao, Xuhong, Ning, Yu, Wang, Lisha, Kunju, Lakshmi P., de Sarkar, Navonil, Heath, Elisabeth I., Chou, Jonathan, Feng, Felix Y., Nelson, Peter S., de Bono, Johann S., Zou, Weiping, Montgomery, Bruce, Alva, Ajjai, Robinson, Dan R., Chinnaiyan, Arul M.

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Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B von Sun, Yu, Campisi, Judith, Higano, Celestia, Beer, Tomasz M, Porter, Peggy, Coleman, Ilsa, True, Lawrence, Nelson, Peter S

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Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress von Nyquist, Michael D., Corella, Alexandra, Coleman, Ilsa, De Sarkar, Navonil, Kaipainen, Arja, Ha, Gavin, Gulati, Roman, Ang, Lisa, Chatterjee, Payel, Lucas, Jared, Pritchard, Colin, Risbridger, Gail, Isaacs, John, Montgomery, Bruce, Morrissey, Colm, Corey, Eva, Nelson, Peter S.

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor von Coppé, Jean-Philippe, Patil, Christopher K, Rodier, Francis, Sun, Yu, Muñoz, Denise P, Goldstein, Joshua, Nelson, Peter S, Desprez, Pierre-Yves, Campisi, Judith

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Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer von RONG HU, CHANGXUE LU, PLYMATE, Stephen R, JUN LUO, MOSTAGHEL, Elahe A, YEGNASUBRAMANIAN, Srinivasan, GUREL, Meltem, TANNAHILL, Clare, EDWARDS, Joanne, ISAACS, William B, NELSON, Peter S, BLUEMN, Eric

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The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance von Beltran, Himisha, Hruszkewycz, Andrew, Scher, Howard I, Hildesheim, Jeffrey, Isaacs, Jennifer, Yu, Evan Y, Kelly, Kathleen, Lin, Daniel, Dicker, Adam, Arnold, Julia, Hecht, Toby, Wicha, Max, Sears, Rosalie, Rowley, David, White, Richard, Gulley, James L, Lee, John, Diaz Meco, Maria, Small, Eric J, Shen, Michael, Knudsen, Karen, Goodrich, David W, Lotan, Tamara, Zoubeidi, Amina, Sawyers, Charles L, Rudin, Charles M, Loda, Massimo, Thompson, Timothy, Rubin, Mark A, Tawab-Amiri, Abdul, Dahut, William, Nelson, Peter S

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LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an­­d Serve as Models for Evaluating Cancer Therapeutics von Nguyen, Holly M., Vessella, Robert L., Morrissey, Colm, Brown, Lisha G., Coleman, Ilsa M., Higano, Celestia S., Mostaghel, Elahe A., Zhang, Xiaotun, True, Lawrence D., Lam, Hung‐Ming, Roudier, Martine, Lange, Paul H., Nelson, Peter S., Corey, Eva

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Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer von Li, Shangze, Fong, Ka-Wing, Gritsina, Galina, Zhang, Ali, Zhao, Jonathan C, Kim, Jung, Sharp, Adam, Yuan, Wei, Aversa, Caterina, Yang, Ximing J, Nelson, Peter S, Feng, Felix Y, Chinnaiyan, Arul M, de Bono, Johann S, Morrissey, Colm, Rettig, Matthew B, Yu, Jindan

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A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer von Schweizer, Michael T, Haugk, Kathleen, McKiernan, Jožefa S, Gulati, Roman, Cheng, Heather H, Maes, Jessica L, Dumpit, Ruth F, Nelson, Peter S, Montgomery, Bruce, McCune, Jeannine S, Plymate, Stephen R, Yu, Evan Y

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Molecular Pathways: Involving Microenvironment Damage Responses in Cancer Therapy Resistance von YU SUN, NELSON, Peter S

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ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors von Nguyen, Liem T., Tretiakova, Maria S., Silvis, Mark R., Lucas, Jared, Klezovitch, Olga, Coleman, Ilsa, Bolouri, Hamid, Kutyavin, Vassily I., Morrissey, Colm, True, Lawrence D., Nelson, Peter S., Vasioukhin, Valeri

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Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer von ZIYANG YU, SEN CHEN, SOWALSKY, Adam G, VOZNESENSKY, Olga S, MOSTAGHEL, Elahe A, NELSON, Peter S, CHANGMENG CAI, BALK, Steven P

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