Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis von El-Naggar, Amal M., Veinotte, Chansey J., Cheng, Hongwei, Grunewald, Thomas G.P., Negri, Gian Luca, Somasekharan, Syam Prakash, Corkery, Dale P., Tirode, Franck, Mathers, Joan, Khan, Debjit, Kyle, Alastair H., Baker, Jennifer H., LePard, Nancy E., McKinney, Steven, Hajee, Shamil, Bosiljcic, Momir, Leprivier, Gabriel, Tognon, Cristina E., Minchinton, Andrew I., Bennewith, Kevin L., Delattre, Olivier, Wang, Yuzhuo, Dellaire, Graham, Berman, Jason N., Sorensen, Poul H.

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Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss von Zhu, Xianbing, Fu, Zheng, Chen, Shary Y., Ong, Dionzie, Aceto, Giulio, Ho, Rebecca, Steinberger, Jutta, Monast, Anie, Pilon, Virginie, Li, Eunice, Ta, Monica, Ching, Kyle, Adams, Bianca N., Negri, Gian L., Choiniere, Luc, Fu, Lili, Pavlakis, Kitty, Pirrotte, Patrick, Avizonis, Daina Z., Trent, Jeffrey, Weissman, Bernard E., Klein Geltink, Ramon I., Morin, Gregg B., Park, Morag, Huntsman, David G., Foulkes, William D., Wang, Yemin, Huang, Sidong

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Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance von Lim, Jonathan K. M., Delaidelli, Alberto, Minaker, Sean W., Zhang, Hai-Feng, Colovic, Milena, Yang, Hua, Negri, Gian Luca, von Karstedt, Silvia, Lockwood, William W., Schaffer, Paul, Leprivier, Gabriel, Sorensen, Poul H.

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Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine von Cetinbas, Naniye Mallı, Sudderth, Jessica, Harris, Robert C., Cebeci, Aysun, Negri, Gian L., Yılmaz, Ömer H., DeBerardinis, Ralph J., Sorensen, Poul H.

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The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells von Streubel, Gundula, Watson, Ariane, Jammula, Sri Ganesh, Scelfo, Andrea, Fitzpatrick, Darren J., Oliviero, Giorgio, McCole, Rachel, Conway, Eric, Glancy, Eleanor, Negri, Gian Luca, Dillon, Eugene, Wynne, Kieran, Pasini, Diego, Krogan, Nevan J., Bracken, Adrian P., Cagney, Gerard

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Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression von Konwar, Chaini, Asiimwe, Rebecca, Inkster, Amy M, Merrill, Sarah M, Negri, Gian L, Aristizabal, Maria J, Rider, Christopher F, MacIsaac, Julie L, Carlsten, Christopher, Kobor, Michael S

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Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes von Asleh, Karama, Negri, Gian Luca, Spencer Miko, Sandra E., Colborne, Shane, Hughes, Christopher S., Wang, Xiu Q., Gao, Dongxia, Gilks, C. Blake, Chia, Stephen K. L., Nielsen, Torsten O., Morin, Gregg B.

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The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level von Kwon, Eunjeong, Todorova, Kristina, Wang, Jun, Horos, Rastislav, Lee, Kevin K., Neel, Victor A., Negri, Gian Luca, Sorensen, Poul H., Lee, Sam W., Hentze, Matthias W., Mandinova, Anna

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Quantitative genetic-interaction mapping in mammalian cells von Roguev, Assen, Talbot, Dale, Negri, Gian Luca, Shales, Michael, Cagney, Gerard, Bandyopadhyay, Sourav, Panning, Barbara, Krogan, Nevan J

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The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition von Aristizabal, Maria J, Negri, Gian Luca, Kobor, Michael S

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Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma von Negri, Gian Luca, Grande, Bruno M, Delaidelli, Alberto, El‐Naggar, Amal, Cochrane, Dawn, Lau, Ching C, Triche, Timothy J, Moore, Richard A, Jones, Steven JM, Montpetit, Alexandre, Marra, Marco A, Malkin, David, Morin, Ryan D, Sorensen, Poul H

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Tropical Laurent series, their tropical roots, and localization results for the eigenvalues of nonlinear matrix functions von Negri Porzio, Gian, Noferini, Vanni, Robol, Leonardo

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The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation von Korver, Wouter, Wong, Alan, Gebremeskel, Simon, Negri, Gian Luca, Schanin, Julia, Chang, Katherine, Leung, John, Benet, Zachary, Luu, Thuy, Brock, Emily C, Luehrsen, Kenneth, Xu, Alan, Youngblood, Bradford A

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High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8 von Aristizabal, Maria J, Negri, Gian Luca, Benschop, Joris J, Holstege, Frank C P, Krogan, Nevan J, Kobor, Michael S

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Robust Rational Approximations of Nonlinear Eigenvalue Problems von Güttel, Stefan, Negri Porzio, Gian Maria, Tisseur, Françoise

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Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma von Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.

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O15: Human endometrial organoid model implicates G6PD-dependant metabolism as a potential targetable pathway in ARID1A mutant gynecological cancers von Kalantari, Forouh, Cochrane, Dawn, El Naggar, Amal, Hughes, Christopher, Vallejos, Rodrigo, Douglas, Maxwell, Wang, Yemin, Chow, Christine, Negri, Gian, Morin, Gregg, Huntsman, David

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Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal von Streubel, Gundula, Fitzpatrick, Darren J, Oliviero, Giorgio, Scelfo, Andrea, Moran, Bruce, Das, Sudipto, Munawar, Nayla, Watson, Ariane, Wynne, Kieran, Negri, Gian Luca, Dillon, Eugene T, Jammula, SriGanesh, Hokamp, Karsten, O'Connor, Darran P, Pasini, Diego, Cagney, Gerard, Bracken, Adrian P

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HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases von Kogler, Melanie, Tortola, Luigi, Negri, Gian Luca, Leopoldi, Alexandra, El-Naggar, Amal M, Mereiter, Stefan, Gomez-Diaz, Carlos, Nitsch, Roberto, Tortora, Davide, Kavirayani, Anoop M, Gapp, Bianca V, Rao, Shuan, Uribesalgo, Iris, Hoffmann, David, Cikes, Domagoj, Novatchkova, Maria, Williams, David A, Trent, Jeffrey M, Ikeda, Fumiyo, Daugaard, Mads, Hagelkruys, Astrid, Sorensen, Poul H, Penninger, Josef M

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eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response von Jan, Asad, Jansonius, Brandon, Delaidelli, Alberto, Somasekharan, Syam Prakash, Bhanshali, Forum, Vandal, Milène, Negri, Gian Luca, Moerman, Don, MacKenzie, Ian, Calon, Frédéric, Hayden, Michael R., Taubert, Stefan, Sorensen, Poul H.

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