The impact of SF3B1 mutations in CLL on the DNA-damage response von te Raa, G D, Derks, I A M, Navrkalova, V, Skowronska, A, Moerland, P D, van Laar, J, Oldreive, C, Monsuur, H, Trbusek, M, Malcikova, J, Lodén, M, Geisler, C H, Hüllein, J, Jethwa, A, Zenz, T, Pospisilova, S, Stankovic, T, van Oers, M H J, Kater, A P, Eldering, E

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Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting von Sutton, Lesley-Ann, Ljungström, Viktor, Mansouri, Larry, Young, Emma, Cortese, Diego, Navrkalova, Veronika, Malcikova, Jitka, Muggen, Alice F, Trbusek, Martin, Panagiotidis, Panagiotis, Davi, Frederic, Belessi, Chrysoula, Langerak, Anton W, Ghia, Paolo, Pospisilova, Sarka, Stamatopoulos, Kostas, Rosenquist, Richard

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GENOMIC ABERRATIONS DETECTED IN CIRCULATING TUMOR DNA FROM CEREBROSPINAL FLUID AND PLASMA OF PATIENTS WITH PRIMARY AND SECONDARY CNS LYMPHOMAS WITH NEGATIVE FLOWCYTOMETRY von Mareckova, A., Navrkalova, V., Bohunova, M., Hrabcakova, V., Hricko, S., Reigl, T., Porc, J., Janikova, A., Kotaskova, J.

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EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia von Young, E, Noerenberg, D, Mansouri, L, Ljungström, V, Frick, M, Sutton, L-A, Blakemore, S J, Galan-Sousa, J, Plevova, K, Baliakas, P, Rossi, D, Clifford, R, Roos-Weil, D, Navrkalova, V, Dörken, B, Schmitt, C A, Smedby, K E, Juliusson, G, Giacopelli, B, Blachly, J S, Belessi, C, Panagiotidis, P, Chiorazzi, N, Davi, F, Langerak, A W, Oscier, D, Schuh, A, Gaidano, G, Ghia, P, Xu, W, Fan, L, Bernard, O A, Nguyen-Khac, F, Rassenti, L, Li, J, Kipps, T J, Stamatopoulos, K, Pospisilova, S, Zenz, T, Oakes, C C, Strefford, J C, Rosenquist, R, Damm, F

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P620: DYNAMICS OF GENOMIC ABERRATIONS IN RELATION TO DISEASE ACTIVITY IN UNTREATED PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA von Navrkalova, V., Kotaskova, J., Plevova, K., Reigl, T., Valisova, M., Bohunova, M., Zenatova, M., Radova, L., Panovska, A., Pospisilova, S.

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P614: SUBCLONAL ARCHITECTURE OF CHROMOSOMES REVEALED BY SINGLE‐CELL ANALYSIS OF GENE EXPRESSION IN A PATIENT WITH CLONAL EVOLUTION OF RELAPSING/REFRACTORY CLL von Kotaskova, J., Kurucova, T., Reblova, K., Valisova, M., Zavacka, K., Mareckova, A., Bohunova, M., Pavlova, S., Malcikova, J., Navrkalova, V., Jarosova, M., Doubek, M., Plevova, K., Pospisilova, S.

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Molecular Prognostic Markers and Their Clinical Relevance in Chronic Lymphocytic Leukemia von Navrkalová, V, Kantorová, B, Jarošová, M, Pospíšilová, Š

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Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification von te Raa, G D, Moerland, P D, Leeksma, A C, Derks, I A, Yigittop, H, Laddach, N, Loden-van Straaten, M, Navrkalova, V, Trbusek, M, Luijks, D M, Zenz, T, Skowronska, A, Hoogendoorn, M, Stankovic, T, van Oers, M H, Eldering, E, Kater, A P

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Recurrent mutations refine prognosis in chronic lymphocytic leukemia von Baliakas, P, Hadzidimitriou, A, Sutton, L-A, Rossi, D, Minga, E, Villamor, N, Larrayoz, M, Kminkova, J, Agathangelidis, A, Davis, Z, Tausch, E, Stalika, E, Kantorova, B, Mansouri, L, Scarfò, L, Cortese, D, Navrkalova, V, Rose-Zerilli, M J J, Smedby, K E, Juliusson, G, Anagnostopoulos, A, Makris, A M, Navarro, A, Delgado, J, Oscier, D, Belessi, C, Stilgenbauer, S, Ghia, P, Pospisilova, S, Gaidano, G, Campo, E, Strefford, J C, Stamatopoulos, K, Rosenquist, R

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Molecular Prognostic Markers and Their Clinical Relevance in Chronic Lymphocytic Leukemia von Navrkalová, V, Kantorová, B, Jarošová, M, Pospíšilová, Š

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1.8 MicroRNA Mutational Analysis in Patients with Chronic Lymphocytic Leukemia von Lochmanova, J, Navrkalova, V, Dvorakova, B, Mraz, M, Pavlova, S, Plevova, K, Tichy, B, Malcikova, J, Sebejova, L, Benes, V, Rausch, T, Brychtova, Y, Doubek, M, Trbusek, M, Mayer, J, Pospisilova, S

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ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin von Navrkalova, Veronika, Sebejova, Ludmila, Zemanova, Jana, Kminkova, Jana, Kubesova, Blanka, Malcikova, Jitka, Mraz, Marek, Smardova, Jana, Pavlova, Sarka, Doubek, Michael, Brychtova, Yvona, Potesil, David, Nemethova, Veronika, Mayer, Jiri, Pospisilova, Sarka, Trbusek, Martin

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ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres von Navrkalova, Veronika, Young, Emma, Baliakas, Panagiotis, Radova, Lenka, Sutton, Lesley-Ann, Plevova, Karla, Mansouri, Larry, Ljungström, Viktor, Ntoufa, Stavroula, Davis, Zadie, Juliusson, Gunnar, Smedby, Karin E, Belessi, Chrysoula, Panagiotidis, Panagiotis, Touloumenidou, Tasoula, Davi, Frederic, Langerak, Anton W, Ghia, Paolo, Strefford, Jonathan C, Oscier, David, Mayer, Jiri, Stamatopoulos, Kostas, Pospisilova, Sarka, Rosenquist, Richard, Trbusek, Martin

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ATM Mutations in Major Stereotyped CLL Subsets: Enrichment in Subset #2 is Associated with Unfavourable Outcome von Navrkalova, Veronika, Young, Emma, Baliakas, Panagiotis, Radova, Lenka, Plevova, Karla, Sutton, Lesley-Ann, Mansouri, Larry, Ljungstrom, Viktor, Ntoufa, Stavroula, Davis, Zadie, Juliusson, Gunnar, Smedby, Karin E, Belessi, Chrysoula, Panagiotidis, Panagiotis, Davi, Frederic, Langerak, Anton W., Ghia, Paolo, Strefford, Jonathan C, Oscier, David G, Stamatopoulos, Kostas, Pospisilova, Sarka, Rosenquist, Richard, Trbusek, Martin

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EGR2 Mutations in Chronic Lymphocytic Leukemia: A New Bad Player von Noerenberg, Daniel, Young, Emma, Ljungström, Viktor, Mansouri, Larry, Plevova, Karla, Baliakas, Panagiotis, Blakemore, Stuart, Rossi, Davide, Clifford, Ruth, Navrkalova, Veronika, Sutton, Lesley-Ann, Smedby, Karin E, Juliusson, Gunnar, Belessi, Chrysoula, Panagiotidis, Panagiotis, Chiorazzi, Nicholas, Davi, Frederic, Langerak, Anton W., Schuh, Anna, Gaidano, Gianluca, Strefford, Jonathan C, Ghia, Paolo, Stamatopoulos, Kostas, Pospisilova, Sarka, Zenz, Thorsten, Rosenquist, Richard, Damm, Frederik

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Targeted Next-Generation Sequencing for Mutational Screening in Chronic Lymphocytic Leukemia: A High-Throughput Yet Tailored Approach Will Facilitate Implementation Within a Clinic... von Sutton, L. A., Ljungström, Viktor, Mansouri, Larry, Young, Emma, Cortese, Diego, Navrkalova, V., Malcikova, J., Muggen, A. F., Trbusek, M., Davi, F., Belessi, C., Langerak, A. W., Ghia, P., Pospisilova, S., Stamatopoulos, K., Rosenquist, R.

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'Candidates Phytoplasma prunorum': the phytoplasma infection of Cacopsylla pruni from apricot orchards and from overwintering habitats in Moravia (Czech Republic) von Fialova, R, Navratil, M, Lauterer, P, Navrkalova, V

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The effect of SF3B1 mutation on the DNA damage response and nonsense-mediated mRNA decay in cancer von Leeksma, A.C., Derks, I.A.M., Kasem, M.H., Kilic, E., Klein, A. de, Jager, M.J., Loosdrecht, A.A. van de, Jansen, J.H., Navrkalova, V., Faber, L.M., Zaborsky, N., Egle, A., Zenz, T., Pospisilova, S., Abdel-Wahab, O., Kater, A.P., Eldering, E.

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