International cancer seminars: a focus on kidney cancer von Scelo, G., Hofmann, J.N., Banks, R.E., Bigot, P., Bhatt, R.S., Cancel-Tassin, G., Chew, S.K., Creighton, C.J., Cussenot, O., Davis, I.J., Escudier, B., Frayling, T.M., Häggström, C., Hildebrandt, M.A.T., Holcatova, I., Johansson, M., Linehan, W.M., McDermott, D.F., Nathanson, K.L., Ogawa, S., Perlman, E.J., Purdue, M.P., Stattin, P., Swanton, C., Vasudev, N.S., Wu, X., Znaor, A., Brennan, P., Chanock, S.J.

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Population-based germline breast cancer gene association studies and meta-analysis to inform wider mainstream testing von Rowlands, C.F., Allen, S., Balmaña, J., Domchek, S.M., Evans, D.G., Hanson, H., Hoogerbrugge, N., James, P.A., Nathanson, K.L., Robson, M., Tischkowitz, M., Foulkes, W.D., Turnbull, C.

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Germline Mutations in BRCA1 and BRCA2 in Breast-Ovarian Families From a Breast Cancer Risk Evaluation Clinic von MARTIN, A.-M, BLACKWOOD, M. A, NATHANSON, K. L, ANTIN-OZERKIS, D, SHIH, H. A, CALZONE, K, COLLIGON, T. A, SEAL, S, COLLINS, N, STRATTON, M. R, WEBER, B. L

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CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations von Smalley, K S M, Xiao, M, Villanueva, J, Nguyen, T K, Flaherty, K T, Letrero, R, Van Belle, P, Elder, D E, Wang, Y, Nathanson, K L, Herlyn, M

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MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines von Vultur, A, Villanueva, J, Krepler, C, Rajan, G, Chen, Q, Xiao, M, Li, L, Gimotty, P A, Wilson, M, Hayden, J, Keeney, F, Nathanson, K L, Herlyn, M

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CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature von Sargen, M.R., Merrill, S.L., Chu, E.Y., Nathanson, K.L.

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Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes von Melchor, L, Honrado, E, García, M J, Álvarez, S, Palacios, J, Osorio, A, Nathanson, K L, Benítez, J

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Human skin neural crest progenitor cells are susceptible to [BRAF.sup.V600E]-induced transformation von Kumar, S.M, Dai, J, Li, S, Yang, R, Yu, H, Nathanson, K.L, Liu, S, Zhou, H, Guo, J, Xu, X

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Low penetrance genes associated with increased risk for breast cancer von Weber, B.L, Nathanson, K.L

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Breast and prostate cancer risks for male BRCA1 and BRCA2 pathogenic variant carriers using polygenic risk scores von Barnes, D.R., Silvestri, V., Leslie, G., McGuffog, L., Dennis, J., Adlard, J., Agnarsson, B.A., Ahmed, M., Aittomaki, K., Andrulis, I.L., Arason, A., Arnold, N., Barkardottir, R.B., Barrowdale, D., Barwell, J., Belotti, M., Berthet, P., Boonen, S.E., Borg, A., Bozsik, A., Brady, A.F., Brewer, C., Bucalo, A., Buys, S.S., Caldes, T., Christensen, L.L., Cini, G., Claes, K.B.M., Cook, J., Coppa, A., Cortesi, L., Damante, G., Davidson, R., Hoya, M. de la, Leeneer, K. de, Valle, J. del, Diez, O., Donaldson, A., Engel, C., Feliubadalo, L., Frone, M., Gallagher, D., Giraud, S., Glendon, G., Godwin, A.K., Goldgar, D.E., Greene, M.H., Gregory, H., Gross, E., Hahnen, E., Hentschel, J., Izatt, L., Janavicius, R., Jensen, U.B., Kramer, G., Kroeldrup, L., Kruse, T.A., Lazaro, C., Lesueur, F., Mai, P.L., Manoukian, S., Matrai, Z., Matricardi, L., Mebirouk, N., Monteiro, A.N., Morrison, P.J., Murray, A., Nathanson, K.L., Neuhausen, S.L., Tu, N.D., Parsons, M.T., Pedersen, I.S., Peterlongo, P., Petersen, A.H., Pinto, P., Pottinger, C., Pujana, M.A., Radice, P., Rantala, J., Robson, M., Rump, A., Abajo, A.M.S. de, Stadler, Z., Stoppa-Lyonnet, D., Sutter, C., Teixeira, M.R., Teule, A., Tischkowitz, M., Toland, A.E., Toss, A., Trainer, A.H., Tripathi, V., Valentini, V., Venturelli, M., Vijai, J., Wang-Gohrke, S., Wappenschmidt, B., Offit, K., Easton, D.F., Chenevix-Trench, G.

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The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA... von Lakeman, I.M.M., Broek, A.J. van den, Vos, J.A.M., Barnes, D.R., Adlard, J., Andrulis, I.L., Arason, A., Arun, B.K., Balmana, J., Benitez, J., Borg, A., Caldes, T., Caligo, M.A., Chung, W.K., Collee, J.M., Couch, F.J., Daly, M.B., Dennis, J., Dhawan, M., Domchek, S.M., Eeles, R., Engel, C., Evans, D.G., Feliubadalo, L., Foretova, L., Friedman, E., Frost, D., Ganz, P.A., Garber, J., Gayther, S.A., Gerdes, A.M., Godwin, A.K., Hake, C.R., Hamann, U., Hogervorst, F.B.L., Hooning, M.J., Hopper, J.L., Hulick, P.J., Imyanitov, E.N., Isaacs, C., Izatt, L., Jakubowska, A., James, P.A., Janavicius, R., Jensen, U.B., John, E.M., Joseph, V., Karlan, B.Y., Kets, C.M., Konstantopoulou, I., Kwong, A., Legrand, C., Leslie, G., Lesueur, F., Loud, J.T., Lubinski, J., Manoukian, S., McGuffog, L., Miller, A., Gomes, D.M., Montagna, M., Mouret-Fourme, E., Nathanson, K.L., Neuhausen, S.L., Yie, J.N.Y., Olopade, O.I., Park, S.K., Parsons, M.T., Peterlongo, P., Radice, P., Rantala, J., Rennert, G., Schmutzler, R.K., Simard, J., Singer, C.F., Stadler, Z., Stoppa-Lyonnet, D., Sutter, C., Tan, Y.Y., Teixeira, M.R., Teo, S.H., Teule, A., Thomassen, M., Thull, D.L., Tischkowitz, M., Toland, A.E., Tung, N., Rensburg, E.J. van, Vega, A., Wappenschmidt, B., Devilee, P., Asperen, C.J. van, Bernstein, J.L., Offit, K., Easton, D.F., Rookus, M.A., Chenevix-Trench, G., Antoniou, A.C., Robson, M., Schmidt, M.K.

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CDKN2A mutations with p14 loss predisposing to multiple nerve sheath tumours, melanoma, dysplastic naevi and internal malignancies: a case series and review of the literature von Sargen, M.R., Merrill, S.L., Chu, E.Y., Nathanson, K.L.

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 von Fang, J., Jia, J.P., Makowski, M., Xu, M., Wang, Z.M., Zhang, T.W., Hoskins, J.W., Choi, J., Han, Y.H., Zhang, M.F., Thomas, J., Kovacs, M., Collins, I., Dzyadyk, M., Thompson, A., O'Neill, M., , S. das, Lan, Q., Koster, R., Stolzenberg-Solomon, R.S., Kraft, P., Wolpin, B.M., Jansen, P.W.T.C., Olson, S., McGlynn, K.A., Kanetsky, P.A., Chatterjee, N., Barrett, J.H., Dunning, A.M., Taylor, J.C., Newton-Bishop, J.A., Bishop, D.T., Andresson, T., Petersen, G.M., Amos, C.I., Iles, M.M., Nathanson, K.L., Landi, M.T., Vermeulen, M., Brown, K.M., Amundadottir, L.T.

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Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer... von Hamdi, Y., Pastinen, T., Droit, A., Lemacon, A., Adlard, J., Aittomaki, K., Andrulis, I.L., Arason, A., Arnold, N., Barjhoux, L., Benitez, J., Berthet, P., Blok, M.J., Bobolis, K., Bonadona, V., Bradbury, A.R., Caligo, M.A., Chiquette, J., Claes, K.B.M., Hoya, M. de la, Leeneer, K. de, Ding, Y.C., Dorfling, C.M., Eccles, D., Eeles, R., Engel, C., Evans, D.G., Fostira, F., Fountzilas, G., Friedman, E., Gayther, S.A., Gerdes, A.M., Glendon, G., Goldgar, D.E., Greene, M.H., Hart, S., Hays, J.L., Hogervorst, F.B.L., Imyanitov, E.N., Isaacs, C., Izatt, L., Jensen, U.B., John, E.M., Just, W., Kaczmarek, K., Kets, C.M., Kriege, M., Laitman, Y., Laurent, M., Lazaro, C., Lesueur, F., Liljegren, A., Loman, N., Loud, J.T., Mazoyer, S., McGuffog, L., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Nussbaum, R.L., Olah, E., Olopade, O.I., Oosterwijk, J.C., Park, S.K., Peissel, B., Segura, P.P., Radice, P., Rappaport-Fuerhauser, C., Rennert, G., Robson, M., Rodriguez, G.C., Schmutzler, R.K., Shah, P.D., Slavin, T.P., Sonderstrup, I.M.H., Southey, M., Spurdle, A.B., Stadler, Z., Stoppa-Lyonnet, D., Sutter, C., Tan, Y., Tea, M.K., Teixeira, M.R., Teule, A., Terry, M.B., Thomassen, M., Tihomirova, L., Tognazzo, S., Toland, A.E., Ouweland, A.M.W. van den, Rensburg, E.J. van, Varon-Mateeva, R., Wappenschmidt, B., Wijnen, J.T., Rebbeck, T., Chenevix-Trench, G., Offit, K., Nord, S., Easton, D.F., Antoniou, A.C.

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Human skin neural crest progenitor cells are susceptible to [BRAF.sup.V600E]-induced transformation von Kumar, S.M, Dai, J, Li, S, Yang, R, Yu, H, Nathanson, K.L, Liu, S, Zhou, H, Guo, J, Xu, X

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MEK inhibition affects STAT3 signaling and invasion in human melanoma cell lines von Vultur, A, Villanueva, J, Krepler, C, Rajan, G, Chen, Q, Xiao, M, Li, L, Gimotty, P.A, Wilson, M, Hayden, J, Keeney, F, Nathanson, K.L, Herlyn, M

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Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk von Gaudet, M.M, Klein, R.J, Kirchhoff, T, McGuffog, L, Dunning, A.M, Lee, A, Dennis, J, Healey, S, Dicks, E, Sinilnikova, O, Pankratz, V.S, Wang, X, Eldridge, R.C, Tessier, D.C, Bacot, F, Hogervorst, F.B.L, Peock, S, Stoppa-Lyonnet, D, Peterlongo, P, Schmutzler, R.K, Nathanson, K.L, Piedmonte, M, Singer, C.F, Hansen, T.V.O, Neuhausen, S.L, Garber, J, Weitzel, J.N, Andrulis, I.L, Goldgar, D.E, D'Andrea, E, Caldes, T, Nevanlinna, H, Osorio, A, van Rensburg, E.J, Arason, A, van den Ouweland, A.M.W, van der Hout, A.H, Kets, C.M, Wijnen, J.T, Ausems, M.G.E.M, Frost, D, Platte, R, Evans, D.G, Jacobs, C, Tischkowitz, M, Damiola, F, Golmard, L, Barjhoux, L, Belotti, M, Ferrer, S.F, Spurdle, A.B, Manoukian, S, Genuardi, M, Arnold, N, Sutter, C, Wappenschmidt, B, Pfeiler, G, Friedman, E, Jensen, U.B, Robson, M, Shah, S, Mai, P.L, Fasching, P.A, Peto, J, Humphreys, M.K, Michailidou, K, Sawyer, E.J, Burwinkel, B, Guenel, P, Milne, R.L, Brenner, H, Lochmann, M, Aittomaki, K, Doerk, T, Margolin, S, Mannermaa, A, Lambrechts, D, Chang-Claude, J, Radice, P, Giles, G.G, Winqvist, R, Garcia-Closas, M, Schoof, N, Hooning, M.J, Cox, A, Jakubowska, A, Orr, N, Pita, G, Rosario Alonso, M, Hall, P, Couch, F.J, Simard, J, Altshuler, D, Chenevix-Trench, G, Antoniou, A.C, Offit, K, HEBON, EMBRACE, Collaborators, GEMOS, Network, GENICA

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Breast Cancer Risk and 6q22.33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 von Kirchhoff, T, Gaudet, M.M, Antoniou, A.C, Dunning, A.M, Flyger, H, Yoo, K-Y, Noh, D-Y, Ahn, S-H, Dork, T, Karstens, J.H, Hillemanns, P, Olson, J, Vachon, C, Wang, X, Elliott, G, Reed, M.W.R, Burwinkel, B, Brauch, H, Hamann, U, Ko, Y-D, Schmidt, M.K, Van 't Veer, L.J, Braaf, L.M, Fletcher, O, Peto, J, Turnbull, C, Seal, S, Renwick, A, Rahman, N, Yu, J-C, Hsiung, C-N, Southey, M.C, Hopper, J.L, Hammet, F, Van Dorpe, T, Hatse, S, Andrulis, I.L, Bogdanova, N, Rogov, J.I, Prokofieva, D, Khusnutdinova, E, van Asperen, C.J, Devilee, P, Margolin, S, Milne, R.L, Pilar Zamora, M, Benitez, J, Severi, G, Giles, G.G, Spurdle, A.B, Beesley, J, Holland, H, Healey, S, Wang-Gohrke, S, Mannermaa, A, Kosma, V-M, Kauppinen, J, Kataja, V, Agnarsson, B.A, Caligo, M.A, Godwin, A.K, Nevanlinna, H, Heikkinen, T, Lindor, N, Nathanson, K.L, Domchek, S.M, Loman, N, Karlsson, P, Askmalm, M.S, von Wachenfeldt, A, Verheus, M, Rookus, M.A, Oldenburg, R.A, Ligtenberg, M.J, Ausems, M.G.E.M, Aalfs, C.M, Garcia, E.B.G, Peock, S, Cook, M, Frost, D, Pichert, G, Davidson, R, Chu, C, Eccles, D, Ong, K-R, Douglas, F, Hodgson, S, Evans, D.G, Eeles, R, Pharoah, P.D.P, Offit, K, Chenevix-Trench, G, Easton, D.F, Network, GENICA, kConFab, Grp, AOCSS, SWE-BRCA, HEBON, EMBRACE, BCAC-CIMBA

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Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers : Results from a multicenter study von Jakubowska, A, Rozkrut, Dominik, Antoniou, Antonis C, Scott, Rodney J, McGuffog, Lesley, Healy, Sue, Sinilnikova, Olga M, Rennert, Gad, Lejbkowicz, Flavio, Andrulis, Irene L, Glendon, Gord, Thomassen, Mads, Paligo, M, Aretini, Paolo, Kantala, J, Aroer, B, Von Wachenfeldt, A, Loman, N, Kristoffersson, U, Rosenquist, R, Karlsson, P, Stenmark-Askmalm, M, Melin, B, Nathanson, K.L, Domchek, S.M, Byrski, T, Huzarski, T, Gronwald, J, Cybulski, C, Serrano, P, Osorio, A, Ramon y Cajal, Teresa, Tsitlaidou, M, Benítez, J, Gilbert, M, Rookus, M, Aalfs, Cora M, Kluijt, I, Boessenkool-Pape, J.L, Meijers-Heijboer, H.E.J, Oosterwijk, J.C, Van Asperen, C.J, Nelen, M.R, Van Den Ouweland, A.M.W, Devilee, P, Easton, D.F, Frost, D, Platte, R, Ellis, S.D, Fineberg, E, Evans, D.G, Lalloo, F, Eeles, R, Jacobs, C, Adlard, J, Davidson, R, Eccles, D, Cole, T, Godwin, A, Bove, B, Stoppa-Lyonnet, D, Caux-Moncoutier, V, Belotti, M, Tirapo, C, Mazoyer, S, Barjhoux, L, Boutry-Kryza, N, Pujol, P, Coupier, I, Peyrat, J.P, Vennin, P, Muller, D, Fricker, J.P, Johannsson, O.T, Isaacs, C, Schmutzler, R, Wappenschmidt, B, Meindl, A, Arnold, N, Varon-Mateeva, Raymonda, Niederacher, D, Sutter, C, Deissler, H, Preisler-Adams, S, Simard, J, Soucy, P, Durocher, F, Beesley, J, Chen, X, Rebbeck, T, Couch, F, Wang, X, Lindor, N, Fredericksen, Z, Pankratz, V.S, Peterlongo, P, Fortuzzi, S, Mai, P.L, Loud, J.T, Lubinski, J

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CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations von Smalley, K.S.M, Xiao, M, Villanueva, J, Nguyen, T.K, Flaherty, K.T, Letrero, R, Van Belle, P, Elder, D.E, Wang, Y, Nathanson, K.L, Herlyn, M

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