Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy von Liu, Ye, Satz, Jakob S., Vo, My-Nuong, Nangle, Leslie A., Schimmel, Paul, Ackerman, Susan L.

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Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration von Longo-Guess, Chantal M, Sundberg, John P, Davisson, Muriel T, Schimmel, Paul, Ackerman, Susan L, Lee, Jeong Woong, Beebe, Kirk, Jang, Jaeseon, Nangle, Leslie A, Cook, Susan A

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An Active Dominant Mutation of Glycyl-tRNA Synthetase Causes Neuropathy in a Charcot-Marie-Tooth 2D Mouse Model von Seburn, Kevin L., Nangle, Leslie A., Cox, Gregory A., Schimmel, Paul, Burgess, Robert W.

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Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect von Nangle, Leslie A, Zhang, Wei, Xie, Wei, Yang, Xiang-Lei, Schimmel, Paul

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Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses von Adams, Ryan A., Fernandes-Cerqueira, Cátia, Notarnicola, Antonella, Mertsching, Elisabeth, Xu, Zhiwen, Lo, Wing-Sze, Ogilvie, Kathleen, Chiang, Kyle P., Ampudia, Jeanette, Rosengren, Sanna, Cubitt, Andrea, King, David J., Mendlein, John D., Yang, Xiang-Lei, Nangle, Leslie A., Lundberg, Ingrid E., Jakobsson, Per-Johan, Schimmel, Paul

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Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing von Xu, Zhiwen, Wei, Zhiyi, Zhou, Jie J., Ye, Fei, Lo, Wing-Sze, Wang, Feng, Lau, Ching-Fun, Wu, Jingjing, Nangle, Leslie A., Chiang, Kyle P., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul

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Long-range structural effects of a Charcot-Marie-Tooth disease-causing mutation in human glycyl-tRNA synthetase von Xie, Wei, Nangle, Leslie A, Zhang, Wei, Schimmel, Paul, Yang, Xiang-Lei

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Orthogonal use of a human tRNA synthetase active site to achieve multifunctionality von Yang, Xiang-Lei, Zhou, Quansheng, Kapoor, Mili, Guo, Min, Belani, Rajesh, Xu, Xiaoling, Kiosses, William B, Hanan, Melanie, Park, Chulho, Armour, Eva, Do, Minh-Ha, Nangle, Leslie A, Schimmel, Paul

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Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase von Wei, Zhiyi, Xu, Zhiwen, Liu, Xiaotian, Lo, Wing-Sze, Ye, Fei, Lau, Ching-Fun, Wang, Feng, Zhou, Jie J, Nangle, Leslie A, Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul

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Human tRNA synthetase catalytic nulls with diverse functions von Lo, Wing-Sze, Gardiner, Elisabeth, Xu, Zhiwen, Lau, Ching-Fun, Wang, Feng, Zhou, Jie J., Mendlein, John D., Nangle, Leslie A., Chiang, Kyle P., Yang, Xiang-Lei, Au, Kin-Fai, Wong, Wing Hung, Guo, Min, Zhang, Mingjie, Schimmel, Paul

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Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function von Xu, Zhiwen, Lo, Wing-Sze, Beck, David B., Schuch, Luise A., Oláhová, Monika, Kopajtich, Robert, Chong, Yeeting E., Alston, Charlotte L., Seidl, Elias, Zhai, Liting, Lau, Ching-Fun, Timchak, Donna, LeDuc, Charles A., Borczuk, Alain C., Teich, Andrew F., Juusola, Jane, Sofeso, Christina, Müller, Christoph, Pierre, Germaine, Hilliard, Tom, Turnpenny, Peter D., Wagner, Matias, Kappler, Matthias, Brasch, Frank, Bouffard, John Paul, Nangle, Leslie A., Yang, Xiang-Lei, Zhang, Mingjie, Taylor, Robert W., Prokisch, Holger, Griese, Matthias, Chung, Wendy K., Schimmel, Paul

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Development and Characterization of a Novel Neuropilin-2 Antibody for Immunohistochemical Staining of Cancer and Sarcoidosis Tissue Samples von Förster, Sarah, Chong, Yeeting E., Siefker, David, Becker, Yvonne, Bao, Ruizhi, Escobedo, Erik, Qing, Yang, Rauch, Kaitlyn, Burman, Luke, Burkart, Christoph, Kainz, Philipp, Cubitt, Andrea, Muders, Michael, Nangle, Leslie A.

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Secreted Histidyl-tRNA Synthetase Splice Variants Elaborate Major Epitopes for Autoantibodies in Inflammatory Myositis von Zhou, Jie J., Wang, Feng, Xu, Zhiwen, Lo, Wing-Sze, Lau, Ching-Fun, Chiang, Kyle P., Nangle, Leslie A., Ashlock, Melissa A., Mendlein, John D., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul

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Orchestrating Resilience: How Neuropilin-2 and Macrophages Contribute to Cardiothoracic Disease von Dhupar, Rajeev, Powers, Amy A, Eisenberg, Seth H, Gemmill, Robert M, Bardawil, Charles E, Udoh, Hannah M, Cubitt, Andrea, Nangle, Leslie A, Soloff, Adam C

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Regulated Capture by Exosomes of mRNAs for Cytoplasmic tRNA Synthetases von Wang, Feng, Xu, Zhiwen, Zhou, Jie, Lo, Wing-Sze, Lau, Ching-Fun, Nangle, Leslie A., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul

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Enlarging the Amino Acid Set of Escherichia coli by Infiltration of the Valine Coding Pathway von Döring, Volker, Mootz, Henning D., Nangle, Leslie A., Hendrickson, Tamara L., de Crécy-Lagard, Valérie, Schimmel, Paul, Marlière, Philippe

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Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases von Nangle, Leslie A, De Crecy Lagard, Valerie, Doring, Volker, Schimmel, Paul

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Global Effects of Mistranslation from an Editing Defect in Mammalian Cells von Nangle, Leslie A., Motta, Candace M., Schimmel, Paul

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Abstract LB234: The Neuropilin-2 targeting antibody ATYR2810 inhibits non-small cell lung cancer tumor growth in monotherapy and combination therapy von Barber, Alison G., Xu, Zhiwen, Rahman, Justin, Goel, Hira Lal, Mercurio, Arthur M., Burkart, Christoph, Nangle, Leslie A.

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Abstract 1785: Domain-specific antibodies to Neuropilin 2 implicate VEGF-C and not Semaphorin 3F in breast cancer stem cell function von Nangle, Leslie A., Burman, Luke, Goel, Hira L., Xu, Zhiwen, Hamel, Kristina, Bloom, Nathaniel, Mercurio, Arthur M.

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