Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics von Nalefski, Eric A., Patel, Nidhi, Leung, Philip J.Y., Islam, Zeba, Kooistra, Remy M., Parikh, Ishira, Marion, Estelle, Knott, Gavin J., Doudna, Jennifer A., Le Ny, Anne-Laure M., Madan, Damian

Volltext

Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets von Nalefski, Eric A, Kooistra, Remy M, Parikh, Ishira, Hedley, Samantha, Rajaraman, Karunya, Madan, Damian

Volltext

Single-Molecule Detection of Transcription Factor Binding to DNA in Real Time:  Specificity, Equilibrium, and Kinetic Parameters von Nalefski, Eric A, Nebelitsky, Eugene, Lloyd, Janice A, Gullans, Steven R

Volltext

The C2 domain calcium‐binding motif: Structural and functional diversity von Nalefski, Eric A., Falke, Joseph J.

Volltext

Membrane Binding Kinetics of Protein Kinase C βII Mediated by the C2 Domain von Nalefski, Eric A, Newton, Alexandra C

Volltext

Membrane Orientation and Position of the C2 Domain from cPLA2 by Site-Directed Spin Labeling von Frazier, April A, Wisner, Mark A, Malmberg, Nathan J, Victor, Kenneth G, Fanucci, Gail E, Nalefski, Eric A, Falke, Joseph J, Cafiso, David S

Volltext

C2 Domains from Different Ca2+ Signaling Pathways Display Functional and Mechanistic Diversity von Nalefski, Eric A, Wisner, Mark A, Chen, James Z, Sprang, Stephen R, Fukuda, Mitsunori, Mikoshiba, Katsuhiko, Falke, Joseph J

Volltext

Ca2+-Signaling Cycle of a Membrane-Docking C2 Domain von Nalefski, Eric A, Slazas, Molly M, Falke, Joseph J

Volltext

Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines von Qui, Haoqun, Ferrell, Evan P, Nolan, Niamh, Phelps, Bruce H, Tabibiazar, Raymond, Whitney, Duncan H, Naelfski, Eric A

Volltext

Single-molecule detection for femtomolar quantification of proteins in heterogeneous immunoassays von Nalefski, Eric A, D'Antoni, Christina M, Ferrell, Evan P, Lloyd, Janice A, Qiu, Haoqun, Harris, John L, Whitney, Duncan H

Volltext

Location of the Membrane-Docking Face on the Ca2+-Activated C2 Domain of Cytosolic Phospholipase A2 von Nalefski, Eric A, Falke, Joseph J

Volltext

Rapid quantitative analysis using a single molecule counting approach von D’Antoni, Christina M., Fuchs, Martin, Harris, John L., Ko, Hai-Ping, Meyer, Raymond E., Nadel, Mark E., Randall, Jeffrey D., Rooke, Jenny E., Nalefski, Eric A.

Volltext

Cation Charge and Size Selectivity of the C2 Domain of Cytosolic Phospholipase A2 von Nalefski, Eric A, Falke, Joseph J

Volltext

Membrane Orientation and Position of the C2 Domain from cPLA2 by Site-Directed Spin Labeling von Frazier, April A, Wisner, Mark A, Malmberg, Nathan J, Victor, Kenneth G, Fanucci, Gail E, Nalefski, Eric A, Falke, Joseph J, Cafiso, David S

Volltext

An Ion Pair in Class II Major Histocompatibility Complex Heterodimers Critical for Surface Expression and Peptide Presentation (∗) von Nalefski, Eric A., Shaw, Karen T.Y., Rao, Anjana

Volltext

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain von Nalefski, E A, Sultzman, L A, Martin, D M, Kriz, R W, Towler, P S, Knopf, J L, Clark, J D

Volltext

Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A 2 1 1Edited by J. Karn von Xu, Guang-Yi, McDonagh, Thomas, Yu, Hsiang-Ai, Nalefski, Eric A, Clark, James D, Cumming, Dale A

Volltext

Independent Folding and Ligand Specificity of the C2 Calciumdependent Lipid Binding Domain of Cytosolic Phospholipase A2 von Nalefski, Eric A., McDonagh, Thomas, Somers, William, Seehra, Jasbir, Falke, Joseph J., Clark, James D.

Volltext

Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2 von Nalefski, E A, McDonagh, T, Somers, W, Seehra, J, Falke, J J, Clark, J D

Volltext

Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2 von Xu, G Y, McDonagh, T, Yu, H A, Nalefski, E A, Clark, J D, Cumming, D A

Volltext