Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients von Cabagnols, Xénia, Favale, Fabrizia, Pasquier, Florence, Messaoudi, Kahia, Defour, Jean Philippe, Ianotto, Jean Christophe, Marzac, Christophe, Le Couédic, Jean Pierre, Droin, Nathalie, Chachoua, Ilyas, Favier, Remi, Diop, M'boyba Khadija, Ugo, Valérie, Casadevall, Nicole, Debili, Najet, Raslova, Hana, Bellanné-Chantelot, Christine, Constantinescu, Stefan N., Bluteau, Olivier, Plo, Isabelle, Vainchenker, William

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Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation von Bluteau, Dominique, Balduini, Alessandra, Balayn, Nathalie, Currao, Manuela, Nurden, Paquita, Deswarte, Caroline, Leverger, Guy, Noris, Patrizia, Perrotta, Silverio, Solary, Eric, Vainchenker, William, Debili, Najet, Favier, Remi, Raslova, Hana

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Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms von El-Khoury, Mira, Cabagnols, Xénia, Mosca, Matthieu, Vertenoeil, Gaëlle, Marzac, Christophe, Favale, Fabrizia, Bluteau, Olivier, Lorre, Florence, Tisserand, Amandine, Rabadan Moraes, Graciela, Ugo, Valérie, Ianotto, Jean-Christophe, Rey, Jerôme, Solary, Eric, Roy, Lydia, Rameau, Philippe, Debili, Najet, Pasquier, Florence, Casadevall, Nicole, Marty, Caroline, Constantinescu, Stefan N., Raslova, Hana, Vainchenker, William, Plo, Isabelle

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Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies von Saliba, Joseph, Saint-Martin, Cécile, Di Stefano, Antonio, Lenglet, Gaëlle, Marty, Caroline, Keren, Boris, Pasquier, Florence, Valle, Véronique Della, Secardin, Lise, Leroy, Gwendoline, Mahfoudhi, Emna, Grosjean, Sarah, Droin, Nathalie, Diop, M'boyba, Dessen, Philippe, Charrier, Sabine, Palazzo, Alberta, Merlevede, Jane, Meniane, Jean-Côme, Delaunay-Darivon, Christine, Fuseau, Pascal, Isnard, Françoise, Casadevall, Nicole, Solary, Eric, Debili, Najet, Bernard, Olivier A, Raslova, Hana, Najman, Albert, Vainchenker, William, Bellanné-Chantelot, Christine, Plo, Isabelle

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Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42 von Pleines, Irina, Dütting, Sebastian, Cherpokova, Deya, Eckly, Anita, Meyer, Imke, Morowski, Martina, Krohne, Georg, Schulze, Harald, Gachet, Christian, Debili, Najet, Brakebusch, Cord, Nieswandt, Bernhard

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Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling von Lordier, Larissa, Jalil, Abdelali, Aurade, Fréderic, Larbret, Fréderic, Larghero, Jerôme, Debili, Najet, Vainchenker, William, Chang, Yunhua

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RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization von Lordier, Larissa, Bluteau, Dominique, Jalil, Abdelali, Legrand, Céline, Pan, Jiajia, Rameau, Philippe, Jouni, Dima, Bluteau, Olivier, Mercher, Thomas, Leon, Catherine, Gachet, Christian, Debili, Najet, Vainchenker, William, Raslova, Hana, Chang, Yunhua

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ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis von Basso-Valentina, Francesca, Donada, Alessandro, Manchev, Vladimir T, Lisetto, Manuel, Balayn, Nathalie, Martin, Jean Edouard, Muller, Delphine, Oyarzun, Cecilia Paola Marin, Duparc, Hélène, Arkoun, Brahim, Cumin, Alessandro, Faivre, Lionel, Droin, Nathalie, Biunno, Ida, Pecci, Alessandro, Balduini, Alessandra, Debili, Najet, Antony-Debré, Iléana, Marty, Caroline, Vainchenker, William, Plo, Isabelle, Favier, Remi, Raslova, Hana

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Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes von Roy, Anita, Lordier, Larissa, Mazzi, Stefania, Chang, Yunhua, Lapierre, Valérie, Larghero, Jérome, Debili, Najet, Raslova, Hana, Vainchenker, William

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Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect von Messaoudi, Kahia, Ali, Ashfaq, Ishaq, Rameez, Palazzo, Alberta, Sliwa, Dominika, Bluteau, Olivier, Souquère, Sylvie, Muller, Delphine, Diop, Khadija M., Rameau, Philippe, Lapierre, Valérie, Marolleau, Jean-Pierre, Matthias, Patrick, Godin, Isabelle, Pierron, Gérard, Thomas, Steven G., Watson, Stephen P., Droin, Nathalie, Vainchenker, William, Plo, Isabelle, Raslova, Hana, Debili, Najet

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A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene von Manchev, Vladimir T., Hilpert, Morgane, Berrou, Eliane, Elaib, Ziane, Aouba, Achille, Boukour, Siham, Souquere, Sylvie, Pierron, Gerard, Rameau, Philippe, Andrews, Robert, Lanza, François, Bobe, Regis, Vainchenker, William, Rosa, Jean-Philippe, Bryckaert, Marijke, Debili, Najet, Favier, Remi, Raslova, Hana

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A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis von Klimchenko, Olena, Mori, Marcella, DiStefano, Antonio, Langlois, Thierry, Larbret, Frédéric, Lecluse, Yann, Feraud, Olivier, Vainchenker, William, Norol, Françoise, Debili, Najet

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Proplatelet formation is regulated by the Rho/ROCK pathway von Chang, Yunhua, Auradé, Frédéric, Larbret, Frédéric, Zhang, Yanyan, Le Couedic, Jean-Pierre, Momeux, Laurence, Larghero, Jerôme, Bertoglio, Jacques, Louache, Fawzia, Cramer, Elisabeth, Vainchenker, William, Debili, Najet

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MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9 von Gilles, Laure, Bluteau, Dominique, Boukour, Siham, Chang, Yunhua, Zhang, Yanyan, Robert, Thomas, Dessen, Philippe, Debili, Najet, Bernard, Olivier A., Vainchenker, William, Raslova, Hana

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TET2 Deficiency Inhibits Mesoderm and Hematopoietic Differentiation in Human Embryonic Stem Cells von Langlois, Thierry, da Costa Reis Monte‐Mor, Barbara, Lenglet, Gaëlle, Droin, Nathalie, Marty, Caroline, Le Couédic, Jean‐Pierre, Almire, Carole, Auger, Nathalie, Mercher, Thomas, Delhommeau, François, Christensen, Jesper, Helin, Kristian, Debili, Najet, Fuks, François, Bernard, Olivier A., Solary, Eric, Vainchenker, William, Plo, Isabelle

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Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia von Bluteau, Dominique, Gilles, Laure, Hilpert, Morgane, Antony-Debré, Iléana, James, Chloe, Debili, Najet, Camara-Clayette, Valerie, Wagner-Ballon, Orianne, Cordette-Lagarde, Veronique, Robert, Thomas, Ripoche, Hugues, Gonin, Patrick, Swierczek, Sabina, Prchal, Josef, Vainchenker, William, Favier, Remi, Raslova, Hana

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Crucial Role for Endoplasmic Reticulum Stress During Megakaryocyte Maturation von Lopez, Jose J, Palazzo, Alberta, Chaabane, Chiraz, Albarran, Letizia, Polidano, Evelyne, Lebozec, Kristell, Dally, Saoussen, Nurden, Paquita, Enouf, Jocelyne, Debili, Najet, Bobe, Régis

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Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint von Roy, Anita, Lordier, Larissa, Pioche-Durieu, Catherine, Souquere, Sylvie, Roy, Lydia, Rameau, Philippe, Lapierre, Valérie, Le Cam, Eric, Plo, Isabelle, Debili, Najet, Raslova, Hana, Vainchenker, William

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An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia von Plo, Isabelle, Zhang, Yanyan, Le Couédic, Jean-Pierre, Nakatake, Mayuka, Boulet, Jean-Michel, Itaya, Miki, Smith, Steven O, Debili, Najet, Constantinescu, Stefan N, Vainchenker, William, Louache, Fawzia, de Botton, Stéphane

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Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach von Raslova, Hana, Kauffmann, Audrey, Sekkaï, Dalila, Ripoche, Hugues, Larbret, Fréderic, Robert, Thomas, Le Roux, Diana Tronik, Kroemer, Guido, Debili, Najet, Dessen, Philippe, Lazar, Vladimir, Vainchenker, William

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