Regulation of the mammalian heat shock factor 1 von Dayalan Naidu, Sharadha, Dinkova‐Kostova, Albena T.

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KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease von Dayalan Naidu, Sharadha, Dinkova-Kostova, Albena T.

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KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy von Shekh-Ahmad, Tawfeeq, Eckel, Ramona, Dayalan Naidu, Sharadha, Higgins, Maureen, Yamamoto, Masayuki, Dinkova-Kostova, Albena T, Kovac, Stjepana, Abramov, Andrey Y, Walker, Matthew C

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C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape von Dayalan Naidu, Sharadha, Muramatsu, Aki, Saito, Ryota, Asami, Soichiro, Honda, Tadashi, Hosoya, Tomonori, Itoh, Ken, Yamamoto, Masayuki, Suzuki, Takafumi, Dinkova-Kostova, Albena T.

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Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection von Dayalan Naidu, Sharadha, Kostov, Rumen V, Dinkova-Kostova, Albena T

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Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1 von Dayalan Naidu, Sharadha, Suzuki, Takafumi, Yamamoto, Masayuki, Fahey, Jed W., Dinkova‐Kostova, Albena T.

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Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases von Dayalan Naidu, Sharadha, Sutherland, Calum, Zhang, Ying, Risco, Ana, de la Vega, Laureano, Caunt, Christopher J., Hastie, C. James, Lamont, Douglas J., Torrente, Laura, Chowdhry, Sudhir, Benjamin, Ivor J., Keyse, Stephen M., Cuenda, Ana, Dinkova-Kostova, Albena T.

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Transcription factors NRF2 and HSF1 have opposing functions in autophagy von Dayalan Naidu, Sharadha, Dikovskaya, Dina, Gaurilcikaite, Egle, Knatko, Elena V., Healy, Zachary R., Mohan, Hema, Koh, Glenn, Laurell, Axel, Ball, Graeme, Olagnier, David, de la Vega, Laureano, Ganley, Ian G., Talalay, Paul, Dinkova-Kostova, Albena T.

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The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis von Henderson, John, Naidu, Sharadha Dayalan, Dinkova-Kostova, Albena T., Przyborski, Stefan, Stratton, Richard, O'Reilly, Steven

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The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity von Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano

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Detection of thermal shift in cellular Keap1 by protein-protein interaction inhibitors using immunoblot- and fluorescence microplate-based assays von Dayalan Naidu, Sharadha, Dikovskaya, Dina, Moore, Terry W., Dinkova-Kostova, Albena T.

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Pirin, an Nrf2-Regulated Protein, Is Overexpressed in Human Colorectal Tumors von Zhang, Ying, Knatko, Elena V, Higgins, Maureen, Dayalan Naidu, Sharadha, Smith, Gillian, Honda, Tadashi, de la Vega, Laureano, Dinkova-Kostova, Albena T

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The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2 von Dayalan Naidu, Sharadha, Suzuki, Takafumi, Dikovskaya, Dina, Knatko, Elena V., Higgins, Maureen, Sato, Miu, Novak, Miroslav, Villegas, José A., Moore, Terry W., Yamamoto, Masayuki, Dinkova-Kostova, Albena T.

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Downregulation of Keap1 Confers Features of a Fasted Metabolic State von Knatko, Elena V., Tatham, Michael H., Zhang, Ying, Castro, Cecilia, Higgins, Maureen, Dayalan Naidu, Sharadha, Leonardi, Chiara, de la Vega, Laureano, Honda, Tadashi, Griffin, Julian L., Hay, Ronald T., Dinkova-Kostova, Albena T.

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Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity von Olagnier, David, Lababidi, Rassin R., Hadj, Samar Bel, Sze, Alexandre, Liu, Yiliu, Naidu, Sharadha Dayalan, Ferrari, Matteo, Jiang, Yuan, Chiang, Cindy, Beljanski, Vladimir, Goulet, Marie-Line, Knatko, Elena V., Dinkova-Kostova, Albena T., Hiscott, John, Lin, Rongtuan

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SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models von Quinti, Luisa, Casale, Malcolm, Moniot, Sébastien, Pais, Teresa F., Van Kanegan, Michael J., Kaltenbach, Linda S., Pallos, Judit, Lim, Ryan G., Naidu, Sharadha Dayalan, Runne, Heike, Meisel, Lisa, Rauf, Nazifa Abdul, Leyfer, Dmitriy, Maxwell, Michele M., Saiah, Eddine, Landers, John E., Luthi-Carter, Ruth, Abagyan, Ruben, Dinkova-Kostova, Albena T., Steegborn, Clemens, Marsh, J. Lawrence, Lo, Donald C., Thompson, Leslie M., Kazantsev, Aleksey G.

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Nrf2 depletion in the context of loss-of-function Keap1 leads to mitolysosome accumulation von Dayalan Naidu, Sharadha, Angelova, Plamena R., Knatko, Elena V., Leonardi, Chiara, Novak, Miroslav, de la Vega, Laureano, Ganley, Ian G., Abramov, Andrey Y., Dinkova-Kostova, Albena T.

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Author Correction: C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape von Dayalan Naidu, Sharadha, Muramatsu, Aki, Saito, Ryota, Asami, Soichiro, Honda, Tadashi, Hosoya, Tomonori, Itoh, Ken, Yamamoto, Masayuki, Suzuki, Takafumi, Dinkova-Kostova, Albena T.

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Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response von Ryan, Dylan G., Knatko, Elena V., Casey, Alva M., Hukelmann, Jens L., Dayalan Naidu, Sharadha, Brenes, Alejandro J., Ekkunagul, Thanapon, Baker, Christa, Higgins, Maureen, Tronci, Laura, Nikitopolou, Efterpi, Honda, Tadashi, Hartley, Richard C., O’Neill, Luke A.J., Frezza, Christian, Lamond, Angus I., Abramov, Andrey Y., Arthur, J. Simon C., Cantrell, Doreen A., Murphy, Michael P., Dinkova-Kostova, Albena T.

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Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms von Martins, Susana G, Ribeiro, Vanessa, Melo, Catarina, Paulino-Cavaco, Cláudia, Antonini, Dario, Dayalan Naidu, Sharadha, Murtinheira, Fernanda, Fonseca, Inês, Saget, Bérénice, Pita, Mafalda, Fernandes, Diogo R, Gameiro Dos Santos, Pedro, Rodrigues, Gabriela, Zilhão, Rita, Herrera, Federico, Dinkova-Kostova, Albena T, Carlos, Ana Rita, Thorsteinsdóttir, Sólveig

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