Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation von Nagase, Reina, Inoue, Daichi, Pastore, Alessandro, Fujino, Takeshi, Hou, Hsin-An, Yamasaki, Norimasa, Goyama, Susumu, Saika, Makoto, Kanai, Akinori, Sera, Yasuyuki, Horikawa, Sayuri, Ota, Yasunori, Asada, Shuhei, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Takeda, Reina, Tien, Hwei-Fang, Honda, Hiroaki, Abdel-Wahab, Omar, Kitamura, Toshio

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Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels von Inoue, Daichi, Matsumoto, Masaki, Nagase, Reina, Saika, Makoto, Fujino, Takeshi, Nakayama, Keiichi I, Kitamura, Toshio

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Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia von Kadono, Moe, Kanai, Akinori, Nagamachi, Akiko, Shinriki, Satoru, Kawata, Jin, Iwato, Koji, Kyo, Taiichi, Oshima, Kumi, Yokoyama, Akihiko, Kawamura, Takeshi, Nagase, Reina, Inoue, Daichi, Kitamura, Toshio, Inaba, Toshiya, Ichinohe, Tatsuo, Matsui, Hirotaka

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A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1 von Numata, Masashi, Haginoya, Noriyasu, Shiroishi, Machiko, Hirata, Tsuyoshi, Sato-Otsubo, Aiko, Yoshikawa, Kenji, Takata, Yoshimi, Nagase, Reina, Kashimoto, Yoshinori, Suzuki, Makoto, Schulte, Nina, Polier, Gernot, Kurimoto, Akiko, Tomoe, Yumiko, Toyota, Akiko, Yoneyama, Tomoko, Imai, Emi, Watanabe, Kenji, Hamada, Tomoaki, Kanada, Ryutaro, Watanabe, Jun, Kagoshima, Yoshiko, Tokumaru, Eri, Murata, Kenji, Baba, Takayuki, Shinozaki, Taeko, Ohtsuka, Masami, Goto, Koichi, Karibe, Tsuyoshi, Deguchi, Takao, Gocho, Yoshihiro, Yoshida, Masanori, Tomizawa, Daisuke, Kato, Motohiro, Tsutsumi, Shinji, Kitagawa, Mayumi, Abe, Yuki

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Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD) von Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C, Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi

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The molecular basis of myeloid malignancies von KITAMURA, Toshio, INOUE, Daichi, OKOCHI-WATANABE, Naoko, KATO, Naoko, KOMENO, Yukiko, LU, Yang, ENOMOTO, Yutaka, DOKI, Noriko, UCHIDA, Tomoyuki, KAGIYAMA, Yuki, TOGAMI, Katsuhiro, KAWABATA, Kimihito C., NAGASE, Reina, HORIKAWA, Sayuri, HAYASHI, Yasutaka, SAIKA, Makoto, FUKUYAMA, Tomofusa, IZAWA, Kumi, OKI, Toshihiko, NAKAHARA, Fumio, KITAURA, Jiro

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ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation von Saika, Makoto, Inoue, Daichi, Nagase, Reina, Sato, Naru, Tsuchiya, Akiho, Yabushita, Tomohiro, Kitamura, Toshio, Goyama, Susumu

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A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies von Inoue, Daichi, Fujino, Takeshi, Sheridan, Paul, Zhang, Yao-zhong, Nagase, Reina, Horikawa, Sayuri, Li, Zaomin, Matsui, Hirotaka, Kanai, Akinori, Saika, Makoto, Yamaguchi, Rui, Kozuka-Hata, Hiroko, Kawabata, Kimihito Cojin, Yokoyama, Akihiko, Goyama, Susumu, Inaba, Toshiya, Imoto, Seiya, Miyano, Satoru, Xu, Mingjiang, Yang, Feng-Chun, Oyama, Masaaki, Kitamura, Toshio

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SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS von Inoue, D, Kitaura, J, Matsui, H, Hou, H-A, Chou, W-C, Nagamachi, A, Kawabata, K C, Togami, K, Nagase, R, Horikawa, S, Saika, M, Micol, J-B, Hayashi, Y, Harada, Y, Harada, H, Inaba, T, Tien, H-F, Abdel-Wahab, O, Kitamura, T

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Abstract 1132: Development and characterization of a novel orally bioavailable menin-MLL inhibitor for treatment of acute leukemia patients with MLL -rearrangement or NPM1 mutation von Numata, Masashi, Shiroishi, Machiko, Yoshikawa, Kenji, Haginoya, Noriyasu, Hirata, Tsuyoshi, Takata, Yoshimi, Nagase, Reina, Takashima, Kohei, Kurimoto, Akiko, Tanzawa, Fumie, Tomoe, Yumiko, Hamada, Tomoaki, Kanada, Ryutaro, Watanabe, Jun, Kagoshima, Yoshiko, Tokumaru, Eri, Murata, Kenji, Baba, Takayuki, Shinozaki, Taeko, Hashimoto, Kazuyuki, Kato, Motohiro, Tsutsumi, Shinji, Kitagawa, Mayumi, Fujiwara, Kosaku, Abe, Yuki

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Novel roles of ASXL1 in epigenetic regulation von Inoue, Daichi, Horikawa, Sayuri, Matsui, Hirotaka, Nagase, Reina, Saika, Makoto, Kawabata, Kimihito C, Goyama, Susumu, Kitamura, Toshio

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Analysis of MDS mice model induced by ASXL1 and RUNX1 mutants von Nagase, Reina, Inoue, Daichi, Saika, Makoto, Hou, Hsin-An, Chou, Wen-Chien, Kawabata, Kimihito, Harada, Hironori, Kanai, Akinori, Goyama, Susumu, Honda, Hiroaki, Tien, Hwei-Fang, Kitamura, Toshio

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A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm ) downregulates Csf1r , a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm von Togami, Katsuhiro, Kitaura, Jiro, Uchida, Tomoyuki, Inoue, Daichi, Nishimura, Koutarou, Kawabata, Kimihito C, Nagase, Reina, Horikawa, Sayuri, Izawa, Kumi, Fukuyama, Tomofusa, Nakahara, Fumio, Oki, Toshihiko, Harada, Yuka, Harada, Hironori, Aburatani, Hiroyuki, Kitamura, Toshio

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SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS von Inoue, Daichi, Matsui, Hirotaka, Hou, Hsin-An, Chou, Wen-Chien, Nagamachi, Akiko, Kitaura, Jiro, Kawabata, Kimihito Cojin, Togami, Katsuhiro, Nagase, Reina, Horikawa, Sayuri, Saika, Makoto, Micol, Jean-Baptiste, Hayashi, Yasutaka, Harada, Yuka, Harada, Hironori, Tien, Hwei-Fang, Abdel-Wahab, Omar, Kitamura, Toshio

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Additional file 2 of A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1 von Numata, Masashi, Haginoya, Noriyasu, Shiroishi, Machiko, Hirata, Tsuyoshi, Sato-Otsubo, Aiko, Yoshikawa, Kenji, Takata, Yoshimi, Nagase, Reina, Kashimoto, Yoshinori, Suzuki, Makoto, Schulte, Nina, Polier, Gernot, Kurimoto, Akiko, Tomoe, Yumiko, Toyota, Akiko, Yoneyama, Tomoko, Imai, Emi, Watanabe, Kenji, Hamada, Tomoaki, Kanada, Ryutaro, Watanabe, Jun, Kagoshima, Yoshiko, Tokumaru, Eri, Murata, Kenji, Baba, Takayuki, Shinozaki, Taeko, Ohtsuka, Masami, Goto, Koichi, Karibe, Tsuyoshi, Deguchi, Takao, Gocho, Yoshihiro, Yoshida, Masanori, Tomizawa, Daisuke, Kato, Motohiro, Tsutsumi, Shinji, Kitagawa, Mayumi, Abe, Yuki

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VARIANT TYPE ASXL1 KNOCK-IN MOUSE von INOUE DAICHI, NAGASE REINA, KITAMURA TOSHIO

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Structural characteristics of patients with superior vena cava foci initiating atrial fibrillation: Analysis with electrocardiogram‐triggered computed tomography von Oka, Satoshi, Yamagata, Kenichiro, Nishii, Tatsuya, Tonegawa‐Kuji, Reina, Shimamoto, Keiko, Inoue, Yuko, Miyamoto, Koji, Nagase, Satoshi, Aiba, Takeshi, Kusano, Kengo

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Current clinical practice of subcutaneous implantable cardioverter-defibrillator: Analysis using the JROAD-DPC database von Tonegawa-Kuji, Reina, Inoue, Yuko Y., Nakai, Michikazu, Kanaoka, Koshiro, Sumita, Yoko, Miyazaki, Yuichiro, Wakamiya, Akinori, Shimamoto, Keiko, Ueda, Nobuhiko, Wada, Mitsuru, Yamagata, Kenichiro, Ishibashi, Kohei, Miyamoto, Koji, Nagase, Satoshi, Aiba, Takeshi, Iwanaga, Yoshitaka, Miyamoto, Yoshihiro, Kusano, Kengo

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Transvenous lead extraction versus surgical lead extraction or conservative treatment for cardiac implantable electronic device infections: Propensity score‐weighted analyses of a... von Wada, Mitsuru, Inoue, Yuko Y., Nakai, Michikazu, Sumita, Yoko, Tonegawa‐Kuji, Reina, Miyazaki, Yuichiro, Wakamiya, Akinori, Shimamoto, Keiko, Ueda, Nobuhiko, Nakajima, Kenzaburo, Kamakura, Tsukasa, Yamagata, Kenichiro, Ishibashi, Kohei, Miyamoto, Koji, Nagase, Satoshi, Aiba, Takeshi, Iwanaga, Yoshitaka, Miyamoto, Yoshihiro, Kusano, Kengo

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Development of a Meal Support Device for Functional Recovery Using EMG Signals von Saga, Norihiko, Umeki, Reina, Saito, Naoki, Nagase, Jun-Ya, Satoh, Toshiyuki

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