Localizing matrix metalloproteinase activities in the pericellular environment von Murphy, Gillian, Nagase, Hideaki

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TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1 von Carreca, Anna P., Pravatà, Veronica M., Markham, Matthew, Bonelli, Simone, Murphy, Gillian, Nagase, Hideaki, Troeberg, Linda, Scilabra, Simone D.

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Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice von Seubert, Bastian, Grünwald, Barbara, Kobuch, Julia, Cui, Haissi, Schelter, Florian, Schaten, Susanne, Siveke, Jens T., Lim, Ngee H., Nagase, Hideaki, Simonavicius, Nicole, Heikenwalder, Mathias, Reinheckel, Thomas, Sleeman, Jonathan P., Janssen, Klaus‐Peter, Knolle, Percy A., Krüger, Achim

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Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1 von Manka, Szymon W, Carafoli, Federico, Visse, Robert, Bihan, Dominique, Raynal, Nicolas, Farndale, Richard W, Murphy, Gillian, Enghild, Jan J, Hohenester, Erhard, Nagase, Hideaki

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Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes von Ismail, Heba M., Yamamoto, Kazuhiro, Vincent, Tonia L., Nagase, Hideaki, Troeberg, Linda, Saklatvala, Jeremy

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LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages von Schubert, Kristin, Collins, Laura E, Green, Patricia, Nagase, Hideaki, Troeberg, Linda

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The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity von Brew, Keith, Nagase, Hideaki

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Proteases involved in cartilage matrix degradation in osteoarthritis von Troeberg, Linda, Nagase, Hideaki

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Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2) von Santamaria, Salvatore, Yamamoto, Kazuhiro, Botkjaer, Kenneth, Tape, Christopher, Dyson, Michael R, McCafferty, John, Murphy, Gillian, Nagase, Hideaki

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In Vivo Imaging of MMP‐13 Activity Using a Specific Polymer‐FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy von Duro‐Castano, Aroa, Lim, Ngee Han, Tranchant, Isabelle, Amoura, Mehdi, Beau, Fabrice, Wieland, Heike, Kingler, Otmar, Herrmann, Matthias, Nazaré, Marc, Plettenburg, Oliver, Dive, Vincent, Vicent, María J., Nagase, Hideaki

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The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced... von Watanabe, Kenta, Hirata, Michiko, Tominari, Tsukasa, Matsumoto, Chiho, Fujita, Hidenori, Yonekura, Kazuhiko, Murphy, Gillian, Nagase, Hideaki, Miyaura, Chisato, Inada, Masaki

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Differential Regulation of Extracellular Tissue Inhibitor of Metalloproteinases-3 Levels by Cell Membrane-bound and Shed Low Density Lipoprotein Receptor-related Protein 1 von Scilabra, Simone D., Troeberg, Linda, Yamamoto, Kazuhiro, Emonard, Hervé, Thøgersen, Ida, Enghild, Jan J., Strickland, Dudley K., Nagase, Hideaki

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TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5) von Kashiwagi, M, Tortorella, M, Nagase, H, Brew, K

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The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface von Itoh, Yoshifumi, Ito, Noriko, Nagase, Hideaki, Seiki, Motoharu

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MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein von Durigova, Michaela, Nagase, Hideaki, Mort, John S., Roughley, Peter J.

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Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a “TRAP” to incr... von Scilabra, Simone D., Yamamoto, Kazuhiro, Pigoni, Martina, Sakamoto, Kazuma, Müller, Stephan A., Papadopoulou, Alkmini, Lichtenthaler, Stefan F., Troeberg, Linda, Nagase, Hideaki, Kadomatsu, Kenji

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Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity von Poulet, Blandine, Liu, Ke, Plumb, Darren, Vo, Phoung, Shah, Mittal, Staines, Katherine, Sampson, Alexandra, Nakamura, Hiroyuki, Nagase, Hideaki, Carriero, Alessandra, Shefelbine, Sandra, Pitsillides, Andrew A, Bou-Gharios, George

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Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption von Watanabe, Kenta, Tominari, Tsukasa, Hirata, Michiko, Matsumoto, Chiho, Hirata, Junya, Murphy, Gillian, Nagase, Hideaki, Miyaura, Chisato, Inada, Masaki

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Carcinomas Contain a Matrix Metalloproteinase-Resistant Isoform of Type I Collagen Exerting Selective Support to Invasion von MAKAREEVA, Elena, SEJIN HAN, VERA, Juan Carlos, SACKETT, Dan L, HOLMBECK, Kenn, PHILLIPS, Charlotte L, VISSE, Robert, NAGASE, Hideaki, LEIKIN, Sergey

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Functional Differences of the Catalytic and Non-catalytic Domains in Human ADAMTS-4 and ADAMTS-5 in Aggrecanolytic Activity von Fushimi, Kazunari, Troeberg, Linda, Nakamura, Hiroyuki, Lim, Ngee Han, Nagase, Hideaki

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