Mechanisms of resistance to immune checkpoint inhibitors von Nagasaki, Joji, Ishino, Takamasa, Togashi, Yosuke

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Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity von Watanabe, Tomofumi, Ishino, Takamasa, Ueda, Youki, Nagasaki, Joji, Sadahira, Takuya, Dansako, Hiromichi, Araki, Motoo, Togashi, Yosuke

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Immunomodulatory and direct activities of ropeginterferon alfa‐2b on cancer cells in mouse models of leukemia von Sakatoku, Kazuki, Nakashima, Yasuhiro, Nagasaki, Joji, Nishimoto, Mitsutaka, Hirose, Asao, Nakamae, Mika, Koh, Hideo, Hino, Masayuki, Nakamae, Hirohisa

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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment von Zhou, Wenhao, Kawashima, Shusuke, Ishino, Takamasa, Kawase, Katsushige, Ueda, Youki, Yamashita, Kazuo, Watanabe, Tomofumi, Kawazu, Masahito, Dansako, Hiromichi, Suzuki, Yutaka, Nishikawa, Hiroyoshi, Inozume, Takashi, Nagasaki, Joji, Togashi, Yosuke

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A variety of ‘exhausted’ T cells in the tumor microenvironment von Nagasaki, Joji, Togashi, Yosuke

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TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment von Kawashima, Shusuke, Inozume, Takashi, Kawazu, Masahito, Ueno, Toshihide, Nagasaki, Joji, Tanji, Etsuko, Honobe, Akiko, Ohnuma, Takehiro, Kawamura, Tatsuyoshi, Umeda, Yoshiyasu, Nakamura, Yasuhiro, Kawasaki, Tomonori, Kiniwa, Yukiko, Yamasaki, Osamu, Fukushima, Satoshi, Ikehara, Yuzuru, Mano, Hiroyuki, Suzuki, Yutaka, Nishikawa, Hiroyoshi, Matsue, Hiroyuki, Togashi, Yosuke

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T cells with high BCL-2 expression induced by venetoclax impact anti-leukemic immunity “graft-versus-leukemia effects” von Nagasaki, Joji, Nishimoto, Mitsutaka, Koh, Hideo, Okamura, Hiroshi, Nakamae, Mika, Sakatoku, Kazuki, Ido, Kentaro, Kuno, Masatomo, Makuuchi, Yosuke, Takakuwa, Teruhito, Nakashima, Yasuhiro, Hino, Masayuki, Nakamae, Hirohisa

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The First Case of Non-leukemic Sarcoma Composed of Mixed-phenotype Acute Leukemia, B/myeloid, Not Otherwise Specified von Takakuwa, Teruhito, Nakane, Takahiko, Ohsawa, Masahiko, Nagasaki, Joji, Aoyama, Yasutaka, Nishimoto, Mistutaka, Hayashi, Yoshiki, Kuwae, Yuko, Hino, Masayuki, Nakamae, Hirohisa

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Pulmonary Involvement of Acute Myeloid Leukemia Mimicking Transfusion-related Acute Lung Injury von Ido, Kentaro, Aoyama, Yasutaka, Nagasaki, Joji, Koh, Shiro, Ichihara, Hiroyoshi, Harada, Hiroshi, Kawano, Kiyoshi, Tani, Yoshihiko, Matsuyama, Nobuki, Hirayama, Fumiya, Kohsaki, Masatoshi, Takaku, Shuji, Mugitani, Atsuko

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Plasma Levels of Presepsin (Soluble CD14-subtype) as a Novel Prognostic Marker for Hemophagocytic Syndrome in Hematological Malignancies von Nanno, Satoru, Koh, Hideo, Katayama, Takako, Hashiba, Masamichi, Sato, Ayumi, Makuuchi, Yosuke, Nagasaki, Joji, Kuno, Masatomo, Yoshimura, Takuro, Okamura, Hiroshi, Nishimoto, Mitsutaka, Hirose, Asao, Nakamae, Mika, Nakane, Takahiko, Hino, Masayuki, Nakamae, Hirohisa

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Immunologic Significance of CD80/CD86 or Major Histocompatibility Complex-II Expression in Thymic Epithelial Tumors von Ikeda, Hideki, Nagasaki, Joji, Shimizu, Daiki, Katsuya, Yuki, Horinouchi, Hidehito, Hosomi, Yukio, Tanji, Etsuko, Iwata, Takekazu, Itami, Makiko, Kawazu, Masahito, Ohe, Yuichiro, Suzuki, Takuji, Togashi, Yosuke

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Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-1 von Koya, Junji, Saito, Yuki, Kameda, Takuro, Kogure, Yasunori, Yuasa, Mitsuhiro, Nagasaki, Joji, McClure, Marni B, Shingaki, Sumito, Tabata, Mariko, Tahira, Yuki, Akizuki, Keiichi, Kamiunten, Ayako, Sekine, Masaaki, Shide, Kotaro, Kubuki, Yoko, Hidaka, Tomonori, Kitanaka, Akira, Nakano, Nobuaki, Utsunomiya, Atae, Togashi, Yosuke, Ogawa, Seishi, Shimoda, Kazuya, Kataoka, Keisuke

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Optic Neuritis Associated with Myelodysplastic Syndrome Accompanied by Eosinophilic Crisis von Nagasaki, Joji, Nishimoto, Mitsutaka, Nakamae, Hirohisa, Nakane, Takahiko, Koh, Hideo, Yoshimoto, Kumiko, Shiraki, Kunihiko, Hino, Masayuki

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Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients von Mugitani, Atsuko, Ohta, Tadanobu, Aoyama, Yasutaka, Ichihara, Hiroyoshi, Ido, Kentaro, Manabe, Masahiro, Nagasaki, Joji, Furukawa, Yoshio

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Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models von Kemmotsu, Naoya, Zhu, Li, Nagasaki, Joji, Otani, Yoshihiro, Ueda, Youki, Dansako, Hiromichi, Fang, Yue, Date, Isao, Togashi, Yosuke

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The critical role of CD4+ T cells in PD-1 blockade against MHC-II–expressing tumors such as classic Hodgkin lymphoma von Nagasaki, Joji, Togashi, Yosuke, Sugawara, Takeaki, Itami, Makiko, Yamauchi, Nobuhiko, Yuda, Junichiro, Sugano, Masato, Ohara, Yuuki, Minami, Yosuke, Nakamae, Hirohisa, Hino, Masayuki, Takeuchi, Masahiro, Nishikawa, Hiroyoshi

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PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes von Nagasaki, Joji, Inozume, Takashi, Sax, Nicolas, Ariyasu, Ryo, Ishikawa, Masakazu, Yamashita, Kazuo, Kawazu, Masahito, Ueno, Toshihide, Irie, Takuma, Tanji, Etsuko, Morinaga, Takao, Honobe, Akiko, Ohnuma, Takehiro, Yoshino, Mitsuru, Iwata, Takekazu, Kawase, Katsushige, Sasaki, Keita, Hanazawa, Toyoyuki, Kochin, Vitaly, Kawamura, Tatsuyoshi, Matsue, Hiroyuki, Hino, Masayuki, Mano, Hiroyuki, Suzuki, Yutaka, Nishikawa, Hiroyoshi, Togashi, Yosuke

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Low frequency of intracranial progression in advanced NSCLC patients treated with cancer immunotherapies von Kemmotsu, Naoya, Ninomiya, Kiichiro, Kunimasa, Kei, Ishino, Takamasa, Nagasaki, Joji, Otani, Yoshihiro, Michiue, Hiroyuki, Ichihara, Eiki, Ohashi, Kadoaki, Inoue, Takako, Tamiya, Motohiro, Sakai, Kazuko, Ueda, Youki, Dansako, Hiromichi, Nishio, Kazuto, Kiura, Katsuyuki, Date, Isao, Togashi, Yosuke

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High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects von Kawase, Katsushige, Kawashima, Shusuke, Nagasaki, Joji, Inozume, Takashi, Tanji, Etsuko, Kawazu, Masahito, Hanazawa, Toyoyuki, Togashi, Yosuke

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Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity von Mukohara, Fumiaki, Iwata, Kazuma, Ishino, Takamasa, Inozume, Takashi, Nagasaki, Joji, Ueda, Youki, Suzawa, Ken, Ueno, Toshihide, Ikeda, Hideki, Kawase, Katsushige, Saeki, Yuka, Kawashima, Shusuke, Yamashita, Kazuo, Kawahara, Yu, Nakamura, Yasuhiro, Honobe-Tabuchi, Akiko, Watanabe, Hiroko, Dansako, Hiromichi, Kawamura, Tatsuyoshi, Suzuki, Yutaka, Honda, Hiroaki, Mano, Hiroyuki, Toyooka, Shinichi, Kawazu, Masahito, Togashi, Yosuke

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