The role of sphingosine‐1‐phosphate in inflammation and cancer progression von Nagahashi, Masayuki, Abe, Manabu, Sakimura, Kenji, Takabe, Kazuaki, Wakai, Toshifumi

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Next generation sequencing‐based gene panel tests for the management of solid tumors von Nagahashi, Masayuki, Shimada, Yoshifumi, Ichikawa, Hiroshi, Kameyama, Hitoshi, Takabe, Kazuaki, Okuda, Shujiro, Wakai, Toshifumi

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Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate von Takahashi, Hideo, Asaoka, Mariko, Yan, Li, Rashid, Omar M., Oshi, Masanori, Ishikawa, Takashi, Nagahashi, Masayuki, Takabe, Kazuaki

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Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer von Shimada, Yoshifumi, Okuda, Shujiro, Watanabe, Yu, Tajima, Yosuke, Nagahashi, Masayuki, Ichikawa, Hiroshi, Nakano, Masato, Sakata, Jun, Takii, Yasumasa, Kawasaki, Takashi, Homma, Kei-ichi, Kamori, Tomohiro, Oki, Eiji, Ling, Yiwei, Takeuchi, Shiho, Wakai, Toshifumi

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Hypermutation and microsatellite instability in gastrointestinal cancers von Yuza, Kizuki, Nagahashi, Masayuki, Watanabe, Satoshi, Takabe, Kazuaki, Wakai, Toshifumi

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Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis von Nagahashi, Masayuki, Yamada, Akimitsu, Katsuta, Eriko, Aoyagi, Tomoyoshi, Huang, Wei-Ching, Terracina, Krista P, Hait, Nitai C, Allegood, Jeremy C, Tsuchida, Junko, Yuza, Kizuki, Nakajima, Masato, Abe, Manabu, Sakimura, Kenji, Milstien, Sheldon, Wakai, Toshifumi, Spiegel, Sarah, Takabe, Kazuaki

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The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice von Wang, Yongqing, Aoki, Hiroaki, Yang, Jing, Peng, Kesong, Liu, Runping, Li, Xiaojiaoyang, Qiang, Xiaoyan, Sun, Lixin, Gurley, Emily C., Lai, Guanhua, Zhang, Luyong, Liang, Guang, Nagahashi, Masayuki, Takabe, Kazuaki, Pandak, William M., Hylemon, Phillip B., Zhou, Huiping

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Characteristics of female breast cancer in japan: annual report of the National Clinical Database in 2018 von Tada, Keiichiro, Kumamaru, Hiraku, Miyata, Hiroaki, Asaga, Sota, Iijima, Kotaro, Ogo, Etsuyo, Kadoya, Takayuki, Kubo, Makoto, Kojima, Yasuyuki, Tanakura, Kenta, Tamura, Kenji, Nagahashi, Masayuki, Niikura, Naoki, Hayashi, Naoki, Miyashita, Minoru, Yoshida, Masayuki, Ohno, Shinji, Imoto, Shigeru, Jinno, Hiromitsu

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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer von Liang, Jie, Nagahashi, Masayuki, Kim, Eugene Y., Harikumar, Kuzhuvelil B., Yamada, Akimitsu, Huang, Wei-Ching, Hait, Nitai C., Allegood, Jeremy C., Price, Megan M., Avni, Dorit, Takabe, Kazuaki, Kordula, Tomasz, Milstien, Sheldon, Spiegel, Sarah

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Clinical application of ceramide in cancer treatment von Moro, Kazuki, Nagahashi, Masayuki, Gabriel, Emmanuel, Takabe, Kazuaki, Wakai, Toshifumi

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High levels of sphingolipids in human breast cancer von Nagahashi, Masayuki, MD, PhD, Tsuchida, Junko, MD, Moro, Kazuki, MD, Hasegawa, Miki, MD, PhD, Tatsuda, Kumiko, MD, Woelfel, Ingrid A., BS, Takabe, Kazuaki, MD, PhD, FACS, Wakai, Toshifumi, MD, PhD, FACS

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Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine‐1‐phosphate and ceramide in human hepatocellular carcinoma von Nagahashi, Masayuki, Miura, Kohei, Takabe, Kazuaki, Wakai, Toshifumi

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Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis von NAGAHASHI, Masayuki, RAMACHANDRAN, Subramaniam, TAKABE, Kazuaki, KIM, Eugene Y, ALLEGOOD, Jeremy C, RASHID, Omar M, YAMADA, Akimitsu, RENPING ZHAO, MILSTIEN, Sheldon, HUIPING ZHOU, SPIEGEL, Sarah

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Clinical Utility of ypTNM Stage Grouping in the 8th Edition of the American Joint Committee on Cancer TNM Staging System for Esophageal Squamous Cell Carcinoma von Sudo, Natsuru, Ichikawa, Hiroshi, Muneoka, Yusuke, Hanyu, Takaaki, Kano, Yosuke, Ishikawa, Takashi, Hirose, Yuki, Miura, Kohei, Shimada, Yoshifumi, Nagahashi, Masayuki, Sakata, Jun, Kobayashi, Takashi, Bamba, Takeo, Nakagawa, Satoru, Kosugi, Shin-ichi, Wakai, Toshifumi

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Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors von Wakai, Toshifumi, Prasoon, Pankaj, Hirose, Yuki, Shimada, Yoshifumi, Ichikawa, Hiroshi, Nagahashi, Masayuki

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The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2- Breast Cancer von Oshi, Masanori, Takahashi, Hideo, Tokumaru, Yoshihisa, Yan, Li, Rashid, Omar M, Nagahashi, Masayuki, Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki

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The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases von Nagahashi, Masayuki, Yuza, Kizuki, Hirose, Yuki, Nakajima, Masato, Ramanathan, Rajesh, Hait, Nitai C., Hylemon, Phillip B., Zhou, Huiping, Takabe, Kazuaki, Wakai, Toshifumi

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Annual report of the Japanese Breast Cancer Registry for 2017 von Hayashi, Naoki, Kumamaru, Hiraku, Isozumi, Urara, Aogi, Kenjiro, Asaga, Sota, Iijima, Kotaro, Kadoya, Takayuki, Kojima, Yasuyuki, Kubo, Makoto, Miyashita, Minoru, Miyata, Hiroaki, Nagahashi, Masayuki, Niikura, Naoki, Ogo, Etsuyo, Tamura, Kenji, Tanakura, Kenta, Yamamoto, Yutaka, Yoshida, Masayuki, Imoto, Shigeru, Jinno, Hiromitsu

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Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression von Nagahashi, Masayuki, Takabe, Kazuaki, Liu, Runping, Peng, Kesong, Wang, Xiang, Wang, Yun, Hait, Nitai C., Wang, Xuan, Allegood, Jeremy C., Yamada, Akimitsu, Aoyagi, Tomoyoshi, Liang, Jie, Pandak, William M., Spiegel, Sarah, Hylemon, Phillip B., Zhou, Huiping

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Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer von Katsuta, Eriko, MD, PhD, Yan, Li, PhD, Nagahashi, Masayuki, MD, PhD, Raza, Ali, MD, Sturgill, Jamie L., PhD, Lyon, Debra E., RN, PhD, Rashid, Omar M., MD, JD, Hait, Nitai C., PhD, Takabe, Kazuaki, MD, PhD, FACS

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