Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1 von Chen, Hsiao-Yun, Durmaz, Yavuz T., Li, Yixiang, Sabet, Amin H., Vajdi, Amir, Denize, Thomas, Walton, Emily, Laimon, Yasmin Nabil, Doench, John G., Mahadevan, Navin R., Losman, Julie-Aurore, Barbie, David A., Tolstorukov, Michael Y., Rudin, Charles M., Sen, Triparna, Signoretti, Sabina, Oser, Matthew G.

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Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects von Wang, Yufei, Buck, Alicia, Piel, Brandon, Zerefa, Luann, Murugan, Nithyassree, Coherd, Christian D, Miklosi, Andras G, Johal, Haraman, Bastos, Ricardo Nunes, Huang, Kun, Ficial, Miriam, Laimon, Yasmin Nabil, Signoretti, Sabina, Zhong, Zhou, Hoang, Song-My, Kastrunes, Gabriella M, Grimaud, Marion, Fayed, Atef, Yuan, Hsien-Chi, Nguyen, Quang-De, Thai, Tran, Ivanova, Elena V, Paweletz, Cloud P, Wu, Ming-Ru, Choueiri, Toni K, Wee, Jon O, Freeman, Gordon J, Barbie, David A, Marasco, Wayne A

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Epigenomic profiling nominates master transcription factors (TFs) driving sarcomatoid differentiation (SD) of renal cell carcinoma (RCC) von El Zarif, Talal, Semaan, Karl, Eid, Marc, Fortunato, Brad, Nassar, Amin H, Abou Alaiwi, Sarah, Bakouny, Ziad, Shah, Valisha, Maria Saliby, Renee, Seo, Ji-Heui, Labaki, Chris, Saad, Eddy, Garinet, Simon, Matar, Sayed, Ahmar, Nourhan, Nabil Laimon, Yasmin, Mary Lee, Gwo-Shu, Pomerantz, Mark, E Berchuck, Jacob, Viswanathan, Srinivas R, Signoretti, Sabina, Van Allen, Eliezer M, Braun, David, K Choueiri, Toni, L Freedman, Matt, Baca, Sylvan S

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Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma von El Zarif, Talal, Semaan, Karl, Eid, Marc, Seo, Ji-Heui, Garinet, Simon, Davidsohn, Matthew P., Sahgal, Pranshu, Fortunato, Brad, Canniff, John, Nassar, Amin H., Abou Alaiwi, Sarah, Bakouny, Ziad, Lakshminarayanan, Gitanjali, Savignano, Hunter, Lyons, Kevin, Matar, Sayed, Ali, Atef, Saad, Eddy, Saliby, Renee Maria, Cordeiro, Paulo, Zhang, Ziwei, El Ahmar, Nourhan, Laimon, Yasmin Nabil, Labaki, Chris, Shah, Valisha, Freeman, Dory, O’Toole, Jillian, Lee, Gwo-Shu Mary, Hwang, Justin, Pomerantz, Mark, Signoretti, Sabina, Van Allen, Eliezer M., Xie, Wanling, Berchuck, Jacob E., Viswanathan, Srinivas R., Braun, David A., Choueiri, Toni K., Freedman, Matthew L., Baca, Sylvan C.

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Abstract A029: Epigenomic profiling nominates master transcription factors (TFs) driving sarcomatoid differentiation of renal cell carcinoma (RCC) von Semaan, Karl, Zarif, Talal El, Eid, Marc, Shah, Valisha, Fortunato, Brad, Saliby, Renee Maria, Nassar, Amin H., Alaiwi, Sarah Abou, Seo, Ji-Heui, Labaki, Chris, Bakouny, Ziad, Matar, Sayed, Ahmar, Nourhan El, Laimon, Yasmin Nabil, Lee, Gwo-Shu Mary, Pomerantz, Mark, Berchuck, Jacob, Signoretti, Sabina, Van Allen, Eliezer, Choueiri, Toni, Braun, David, Freedman, Matthew, Baca, Sylvan

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Abstract 886: Fine-tuned CAIX targeted CAR-T cells exhibit superior efficacy and mitigate on-target off-tumor side effects von Wang, Yufei, Buck, Alicia, Kastrunes, Gabriella, Abbas, Rabia, Lynch, Michael, Zhong, Zhou, Hoang, Song-My, Miklosi, Andras, Huang, Kun, Cho, Jae-Won, Grimaud, Marion, Razimbaud, Cecile, Chang, Matthew, Fayed, Atef, Apollon, Audrey, Murugan, Nithyassree, Li, Ze-Hua, Thai, Tran, Zerefa, Luann, Piel, Brandon, Ivanova, Elena, Cameron, Amy, Nguyen, Quang-De, Zhu, Zhu, Wei, Kevin, Laimon, Yasmin Nabil, Sheshdeh, Aseman Bagheri, Signoretti, Sabina, Braun, David A., Wu, Catherine J., Choueiri, Toni K., Wee, Jon, Paweletz, Cloud P., Hemberg, Martin, Culhane, Aedin C., Barbie, David A., Freeman, Gordon J., Marasco, Wayne A.

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