Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization von Senturk, Serif, Shirole, Nitin H., Nowak, Dawid G., Corbo, Vincenzo, Pal, Debjani, Vaughan, Alexander, Tuveson, David A., Trotman, Lloyd C., Kinney, Justin B., Sordella, Raffaella

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Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression von Chen, Muhan, Pratt, Christopher P., Zeeman, Martha E., Schultz, Nikolaus, Taylor, Barry S., O'Neill, Audrey, Castillo-Martin, Mireia, Nowak, Dawid G., Naguib, Adam, Grace, Danielle M., Murn, Jernej, Navin, Nick, Atwal, Gurinder S., Sander, Chris, Gerald, William L., Cordon-Cardo, Carlos, Newton, Alexandra C., Carver, Brett S., Trotman, Lloyd C.

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WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing von Amin, Elianna M., Oltean, Sebastian, Hua, Jing, Gammons, Melissa V.R., Hamdollah-Zadeh, Maryam, Welsh, Gavin I., Cheung, Man-Kim, Ni, Lan, Kase, Satoru, Rennel, Emma S., Symonds, Kirsty E., Nowak, Dawid G., Royer-Pokora, Brigitte, Saleem, Moin A., Hagiwara, Masatoshi, Schumacher, Valérie A., Harper, Steven J., Hinton, David R., Bates, David O., Ladomery, Michael R.

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Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors von Nowak, Dawid G, Woolard, Jeanette, Amin, Elianna Mohamed, Konopatskaya, Olga, Saleem, Moin A, Churchill, Amanda J, Ladomery, Michael R, Harper, Steven J, Bates, David O

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Novel genetically engineered mouse models for clear cell renal cell carcinoma von van der Mijn, Johannes C., Laursen, Kristian B., Fu, Leiping, Khani, Francesca, Dow, Lukas E., Nowak, Dawid G., Chen, Qiuying, Gross, Steven S., Nanus, David M., Gudas, Lorraine J.

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Molecular Pathways: PI3K Pathway Phosphatases as Biomarkers for Cancer Prognosis and Therapy von MUHAN CHEN, NOWAK, Dawid G, TROTMAN, Lloyd C

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Regulation of Vascular Endothelial Growth Factor (VEGF) Splicing from Pro-angiogenic to Anti-angiogenic Isoforms: A NOVEL THERAPEUTIC STRATEGY FOR ANGIOGENESIS von Nowak, Dawid G, Amin, Elianna Mohamed, Rennel, Emma S, Hoareau-Aveilla, Coralie, Gammons, Melissa, Damodoran, Gopinath, Hagiwara, Masatoshi, Harper, Steven J, Woolard, Jeanette, Ladomery, Michael R, Bates, David O

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MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2 von Nowak, Dawid G, Cho, Hyejin, Herzka, Tali, Watrud, Kaitlin, DeMarco, Daniel V, Wang, Victoria M Y, Senturk, Serif, Fellmann, Christof, Ding, David, Beinortas, Tumas, Kleinman, David, Chen, Muhan, Sordella, Raffaella, Wilkinson, John E, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Robinson, Brian D, Trotman, Lloyd C

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Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases von Taranda, Julian, Mathew, Grinu, Watrud, Kaitlin, El-Amine, Nour, Lee, Matthew F., Elowsky, Corey, Bludova, Anastasiia, Escobar Avelar, Sintia, Nowak, Dawid G., Wee, Tse-Luen, Wilkinson, John E., Trotman, Lloyd C., Osten, Pavel

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The PHLPP2 phosphatase is a druggable driver of prostate cancer progression von Nowak, Dawid G, Katsenelson, Ksenya Cohen, Watrud, Kaitlin E, Chen, Muhan, Mathew, Grinu, D'Andrea, Vincent D, Lee, Matthew F, Swamynathan, Manojit Mosur, Casanova-Salas, Irene, Jibilian, Megan C, Buckholtz, Caroline L, Ambrico, Alexandra J, Pan, Chun-Hao, Wilkinson, John E, Newton, Alexandra C, Trotman, Lloyd C

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A Tumor Treated With Antibiotics: A Rare Case von Mahmoud, Anas, Nowak, Dawid, Chaudhry, Arslan, Agnelli, Michael

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Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function von Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E, Doherty, Mary R, Gineste, Charlotte, Mathew, Grinu, Gong, Grace Q, Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R, Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N, Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G, Alsudani, Habeeb, Wee, Tse-Luen, Park, Youngkyu, Minicozzi, Francesca, Rivera, Keith, Almeida, Ana S, Chang, Kenneth, Chakrabarty, Ram P, Wilkinson, John E, Gimotty, Phyllis A, Diermeier, Sarah D, Egeblad, Mikala, Vakoc, Christopher R, Locasale, Jason W, Chandel, Navdeep S, Janowitz, Tobias, Hicks, James B, Wigler, Michael, Pappin, Darryl J, Williams, Roger L, Cifani, Paolo, Tuveson, David A, Laporte, Jocelyn, Trotman, Lloyd C

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Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output von Reyes, Gloria, Niederst, Matt, Cohen-Katsenelson, Ksenya, Stender, Joshua D, Kunkel, Maya T, Chen, Muhan, Brognard, John, Sierecki, Emma, Gao, Tianyan, Nowak, Dawid G, Trotman, Lloyd C, Glass, Christopher K, Newton, Alexandra C

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The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein von Chen, Muhan, Nowak, Dawid G, Narula, Navneet, Robinson, Brian, Watrud, Kaitlin, Ambrico, Alexandra, Herzka, Tali M, Zeeman, Martha E, Minderer, Matthias, Zheng, Wu, Ebbesen, Saya H, Plafker, Kendra S, Stahlhut, Carlos, Wang, Victoria M Y, Wills, Lorna, Nasar, Abu, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Wilkinson, John E, Powers, Scott, Sordella, Raffaella, Altorki, Nasser K, Mittal, Vivek, Stiles, Brendon M, Plafker, Scott M, Trotman, Lloyd C

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Utility of Single-Cell Genomics in Diagnostic Evaluation of Prostate Cancer von Alexander, Joan, Kendall, Jude, McIndoo, Jean, Rodgers, Linda, Aboukhalil, Robert, Levy, Dan, Stepansky, Asya, Sun, Guoli, Chobardjiev, Lubomir, Riggs, Michael, Cox, Hilary, Hakker, Inessa, Nowak, Dawid G, Laze, Juliana, Llukani, Elton, Srivastava, Abhishek, Gruschow, Siobhan, Yadav, Shalini S, Robinson, Brian, Atwal, Gurinder, Trotman, Lloyd C, Lepor, Herbert, Hicks, James, Wigler, Michael, Krasnitz, Alexander

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Overexpression of VEGF165b in Podocytes Reduces Glomerular Permeability von YAN QIU, FERGUSON, Joanne, SALMON, Andy H. J, BATES, David, HARPER, Steve J, OLTEAN, Sebastian, NEAL, Chris R, KAURA, Amit, BEVAN, Heather, WOOD, Emma, SAGE, Leslie M, LANATI, Silvia, NOWAK, Dawid G

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Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors von Labbé, David P, Nowak, Dawid G, Deblois, Geneviève, Lessard, Laurent, Giguère, Vincent, Trotman, Lloyd C, Tremblay, Michel L

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Long-term organogenic callus cultivation of Ranunculus illyricus L.: a blueprint for sustainable ex situ conservation of the species in urban greenery von Kocot, Dawid, Nowak, Barbara, Sitek, Ewa

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Tu1141 ANALYSIS OF CIRCULATING TUMOR DNA FOR MALIGNANCIES SENT AT THE TIME OF ENDOSCOPIC VISUALIZATION: AN OPTIMAL STRATEGY FOR DIAGNOSIS AND SELECTION OF TARGETED THERAPIES von Nowak, Dawid, Patel, Dhruv, Adalja, Devina, Grossman, Matthew

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Mobile Chipper Design with FEM System Application von Dzieniszewski, Grzegorz, Nowak, Dawid, Kuboń, Maciej, Furyk-Grabowska, Karolina

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