Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production von Tosello-Trampont, Annie-Carole, Landes, Susan G., Nguyen, Virginia, Novobrantseva, Tatiana I., Hahn, Young S.

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Therapeutic siRNA silencing in inflammatory monocytes in mice von Leuschner, Florian, Dutta, Partha, Gorbatov, Rostic, Novobrantseva, Tatiana I, Donahoe, Jessica S, Courties, Gabriel, Lee, Kang Mi, Kim, James I, Markmann, James F, Marinelli, Brett, Panizzi, Peter, Lee, Won Woo, Iwamoto, Yoshiko, Milstein, Stuart, Epstein-Barash, Hila, Cantley, William, Wong, Jamie, Cortez-Retamozo, Virna, Newton, Andita, Love, Kevin, Libby, Peter, Pittet, Mikael J, Swirski, Filip K, Koteliansky, Victor, Langer, Robert, Weissleder, Ralph, Anderson, Daniel G, Nahrendorf, Matthias

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In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing von Courties, Gabriel, PhD, Heidt, Timo, MD, Sebas, Matthew, BS, Iwamoto, Yoshiko, BS, Jeon, Derrick, MS, Truelove, Jessica, BS, Tricot, Benoit, MS, Wojtkiewicz, Greg, MS, Dutta, Partha, PhD, Sager, Hendrik B., MD, Borodovsky, Anna, PhD, Novobrantseva, Tatiana, PhD, Klebanov, Boris, PhD, Fitzgerald, Kevin, PhD, Anderson, Daniel G., PhD, Libby, Peter, MD, Swirski, Filip K., PhD, Weissleder, Ralph, MD, PhD, Nahrendorf, Matthias, MD, PhD

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Origins of tumor-associated macrophages and neutrophils von Cortez-Retamozo, Virna, Etzrodt, Martin, Newton, Andita, Rauch, Philipp J, Chudnovskiy, Aleksey, Berger, Cedric, Ryan, Russell J. H, Iwamoto, Yoshiko, Marinelli, Brett, Gorbatov, Rostic, Forghani, Reza, Novobrantseva, Tatiana I, Koteliansky, Victor, Figueiredo, Jose-Luiz, Chen, John W, Anderson, Daniel G, Nahrendorf, Matthias, Swirski, Filip K, Weissleder, Ralph, Pittet, Mikael J

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Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders von Fukuda, Daiju, Aikawa, Elena, Swirski, Filip K, Novobrantseva, Tatiana I, Kotelianski, Victor, Gorgun, Cem Z, Chudnovskiy, Aleksey, Yamazaki, Hiroyuki, Croce, Kevin, Weissleder, Ralph, Aster, Jon C, Hotamisligil, Gökhan S, Yagita, Hideo, Aikawa, Masanori

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Silencing of CCR2 in myocarditis von Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J, Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I, Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A, Lin, Charles, Libby, Peter, Swirski, Filip K, Anderson, Daniel G, Weissleder, Ralph, Nahrendorf, Matthias

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Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells von Basha, Genc, Novobrantseva, Tatiana I, Rosin, Nicole, Tam, Yuen Yi C, Hafez, Ismail M, Wong, Matthew K, Sugo, Tsukasa, Ruda, Vera M, Qin, June, Klebanov, Boris, Ciufolini, Marco, Akinc, Akin, Tam, Ying K, Hope, Michael J, Cullis, Pieter R

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Macrophages retain hematopoietic stem cells in the spleen via VCAM-1 von Dutta, Partha, Hoyer, Friedrich Felix, Grigoryeva, Lubov S, Sager, Hendrik B, Leuschner, Florian, Courties, Gabriel, Borodovsky, Anna, Novobrantseva, Tatiana, Ruda, Vera M, Fitzgerald, Kevin, Iwamoto, Yoshiko, Wojtkiewicz, Gregory, Sun, Yuan, Da Silva, Nicolas, Libby, Peter, Anderson, Daniel G, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

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Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation von Hobo, Willemijn, Novobrantseva, Tatiana I., Fredrix, Hanny, Wong, Jamie, Milstein, Stuart, Epstein-Barash, Hila, Liu, Ju, Schaap, Nicolaas, van der Voort, Robbert, Dolstra, Harry

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The roles of individual mammalian argonautes in RNA interference in vivo von Ruda, Vera M, Chandwani, Rohit, Sehgal, Alfica, Bogorad, Roman L, Akinc, Akin, Charisse, Klaus, Tarakhovsky, Alexander, Novobrantseva, Tatiana I, Koteliansky, Victor

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RNA inhibition highlights cyclin D1 as a potential therapeutic target for mantle cell lymphoma von Weinstein, Shiri, Emmanuel, Rafi, Jacobi, Ashley M, Abraham, Avigdor, Behlke, Mark A, Sprague, Andrew G, Novobrantseva, Tatiana I, Nagler, Arnon, Peer, Dan

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Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery von Siegwart, Daniel J., Whitehead, Kathryn A., Nuhn, Lutz, Sahay, Gaurav, Cheng, Hao, Jiang, Shan, Ma, Minglin, Lytton-Jean, Abigail, Vegas, Arturo, Fenton, Patrick, Levins, Christopher G., Love, Kevin T., Lee, Haeshin, Cortez, Christina, Collins, Sean P., Li, Ying Fei, Jang, Janice, Querbes, William, Zurenko, Christopher, Novobrantseva, Tatiana, Langer, Robert, Anderson, Daniel G.

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Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates von Dong, Yizhou, Love, Kevin T., Dorkin, J. Robert, Sirirungruang, Sasilada, Zhang, Yunlong, Chen, Delai, Bogorad, Roman L., Yin, Hao, Chen, Yi, Vegas, Arturo J., Alabi, Christopher A., Sahay, Gaurav, Olejnik, Karsten T., Wang, Weiheng, Schroeder, Avi, Lytton-Jean, Abigail K. R., Siegwart, Daniel J., Akinc, Akin, Barnes, Carmen, Barros, Scott A., Carioto, Mary, Fitzgerald, Kevin, Hettinger, Julia, Kumar, Varun, Novobrantseva, Tatiana I., Qin, June, Querbes, William, Koteliansky, Victor, Langer, Robert, Anderson, Daniel G.

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Attenuated liver fibrosis in the absence of B cells von Novobrantseva, Tatiana I, Majeau, Gerard R, Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, Shlomchik, Mark J, Koteliansky, Victor, Hochman, Paula S, Ibraghimov, Alexander

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VH replacement in primary immunoglobulin repertoire diversification von Sun, Amy, Novobrantseva, Tatiana I, Coffre, Maryaline, Hewitt, Susannah L, Jensen, Kari, Skok, Jane A, Rajewsky, Klaus, Koralov, Sergei B

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Loss of NFAT5 Results in Renal Atrophy and Lack of Tonicity-Responsive Gene Expression von López-Rodríguez, Cristina, Antos, Christopher L., Shelton, John M., Richardson, James A., Lin, Fangming, Novobrantseva, Tatiana I., Bronson, Roderick T., Igarashi, Peter, Rao, Anjana, Olson, Eric N.

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PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages von Kauffman, Kevin, Manfra, Denise, Nowakowska, Dominika, Zafari, Mohammad, Nguyen, Phuong A., Phennicie, Ryan, Vollmann, Elisabeth H., O'Nuallain, Brian, Basinski, Sara, Komoroski, Veronica, Rooney, Kate, Culyba, Elizabeth K., Wahle, Joseph, Ries, Carola, Brehm, Michael, Sazinsky, Steve, Feldman, Igor, Novobrantseva, Tatiana I.

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Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8+ T Cell-mediated Hepatic Antiviral Immunity von Dolina, Joseph S, Sung, Sun-Sang J, Novobrantseva, Tatiana I, Nguyen, Tuyen M, Hahn, Young S

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Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing von Vollmann, Elisabeth H., Cao, Lizhi, Amatucci, Aldo, Reynolds, Taylor, Hamann, Stefan, Dalkilic-Liddle, Isin, Cameron, Thomas O., Hossbach, Markus, Kauffman, Kevin J., Mir, Faryal F., Anderson, Daniel G., Novobrantseva, Tatiana, Koteliansky, Victor, Kisseleva, Tatiana, Brenner, David, Duffield, Jeremy, Burkly, Linda C.

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Antibody repertoires generated by VH replacement and direct VH to JH joining von Koralov, Sergei B, Novobrantseva, Tatiana I, Königsmann, Jessica, Ehlich, Andreas, Rajewsky, Klaus

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