The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes von Northrup, Alan B, MacMillan, David W. C

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Two-Step Synthesis of Carbohydrates by Selective Aldol Reactions von Northrup, Alan B., David W. C. Mac Millan

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Total Synthesis and Structural Revision of Callipeltoside C von Carpenter, Joseph, Northrup, Alan B., Chung, deMichael, Wiener, John J. M., Kim, Sung-Gon, MacMillan, David W. C.

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The Importance of Iminium Geometry Control in Enamine Catalysis: Identification of a New Catalyst Architecture for Aldehyde-Aldehyde Couplings von Mangion, Ian K., Northrup, Alan B., MacMillan, David W. C.

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Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer von Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley

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A New Strategy for the Synthesis of Benzylic Sulfonamides:  Palladium-Catalyzed Arylation and Sulfonamide Metathesis von Grimm, Jonathan B, Katcher, Matthew H, Witter, David J, Northrup, Alan B

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The First General Enantioselective Catalytic Diels−Alder Reaction with Simple α,β-Unsaturated Ketones von Northrup, Alan B, MacMillan, David W. C

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Enantioselective Organocatalytic Direct Aldol Reactions of α-Oxyaldehydes: Step One in a Two-Step Synthesis of Carbohydrates von Northrup, Alan B., Mangion, Ian K., Hettche, Frank, MacMillan, David W. C.

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Analyzing the Potential Root Causes of Variability of Pharmacokinetics in Preclinical Species von Daublain, Pierre, Feng, Kung-I, Altman, Michael D, Martin, Iain, Mukherjee, Suman, Nofsinger, Rebecca, Northrup, Alan B, Tschirret-Guth, Richard, Cartwright, Mark, McGregor, Caroline

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Inhibition of spleen tyrosine kinase attenuates IgE‐mediated airway contraction and mediator release in human precision cut lung slices von Koziol‐White, Cynthia J, Jia, Yanlin, Baltus, Gretchen A, Cooper, Philip R, Zaller, Dennis M, Crackower, Michael A, Sirkowski, Erich E, Smock, Steven, Northrup, Alan B, Himes, Blanca E, Alves, Stephen E, Panettieri, Reynold A

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Overcoming Mutagenicity and Ion Channel Activity: Optimization of Selective Spleen Tyrosine Kinase Inhibitors von Ellis, J. Michael, Altman, Michael D, Bass, Alan, Butcher, John W, Byford, Alan J, Donofrio, Anthony, Galloway, Sheila, Haidle, Andrew M, Jewell, James, Kelly, Nancy, Leccese, Erica K, Lee, Sandra, Maddess, Matthew, Miller, J. Richard, Moy, Lily Y, Osimboni, Ekundayo, Otte, Ryan D, Reddy, M. Vijay, Spencer, Kerrie, Sun, Binyuan, Vincent, Stella H, Ward, Gwendolyn J, Woo, Grace H. C, Yang, Chiming, Houshyar, Hani, Northrup, Alan B

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Discovery of 1‑[3-(1-Methyl‑1H‑pyrazol-4-yl)-5-oxo‑5H‑benzo[4,5]cyclohepta[1,2‑b]pyridin-7-yl]‑N‑(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c‑Met/Ron Dual Kinase... von Northrup, Alan B, Katcher, Matthew H, Altman, Michael D, Chenard, Melissa, Daniels, Matthew H, Deshmukh, Sujal V, Falcone, Danielle, Guerin, David J, Hatch, Harold, Li, Chaomin, Lu, Wei, Lutterbach, Bart, Allison, Timothy J, Patel, Sangita B, Reilly, John F, Reutershan, Michael, Rickert, Keith W, Rosenstein, Craig, Soisson, Stephen M, Szewczak, Alexander A, Walker, Deborah, Wilson, Kevin, Young, Jonathan R, Pan, Bo-Sheng, Dinsmore, Christopher J

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Carboxamide Spleen Tyrosine Kinase (Syk) Inhibitors: Leveraging Ground State Interactions To Accelerate Optimization von Ellis, J. Michael, Altman, Michael D, Cash, Brandon, Haidle, Andrew M, Kubiak, Rachel L, Maddess, Matthew L, Yan, Youwei, Northrup, Alan B

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Total Synthesis and Structural Revision of Callipeltoside C von Carpenter, Joseph, Northrup, Alan B., Chung, deMichael, Wiener, John J. M., Kim, Sung-Gon, MacMillan, David W. C.

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The Importance of Iminium Geometry Control in Enamine Catalysis: Identification of a New Catalyst Architecture for Aldehyde-Aldehyde Couplings von Mangion, Ian K., Northrup, Alan B., MacMillan, David W. C.

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von CUMMING, Jared, N, TROTTER, Benjamin Wesley, LU, Min, CHILDERS, Matthew Lloyd, OTTE, Ryan, D, CHANG, Wonsuk, HAIDLE, Andrew Marc, NORTHRUP, Alan, B, ANDRESEN, Brian, HENDERSON, Timothy, J, JEWELL, James, P, TRUONG, Quang, T, ALTMAN, Michael, D, SIU, Tony

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CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS von CUMMING, Jared, N, TROTTER, Benjamin Wesley, LU, Min, WALSH, Shawn, P, CHILDERS, Matthew Lloyd, OTTE, Ryan, D, CHANG, Wonsuk, ZHAO, Kake, HAIDLE, Andrew Marc, LIM, Jongwon, NORTHRUP, Alan, B, ANDRESEN, Brian, HENDERSON, Timothy, J, LIANG, Rui, LIU, Hong, JEWELL, James, P, TRUONG, Quang, T, ALTMAN, Michael, D, SIU, Tony

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THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS von ELLIS, John Michael, GAUTHIER, Jacques Yves, BUTCHER, John W, ARRINGTON, Kenneth L, NORTHRUP, Alan B, ANDRESEN, Brian M, OTTE, Ryan D, FOURNIER, Jean-Francois, ROBICHAUD, Joel S

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THIAZOLE-SUBSTITUTED AMINOPYRIMIDINES AS SPLEEN TYROSINE KINASE INHIBITORS von WANG, Liping, NORTHRUP, Alan, B, SZEWCZYK, Jason, W, DUBOIS, Byron, ARRINGTON, Kenneth, L, DEBENHAM, John, S, WANG, Ming, LIU, Ping

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Enantioselective Organocatalytic Direct Aldol Reactions of α-Oxyaldehydes: Step One in a Two-Step Synthesis of Carbohydrates von Northrup, Alan B., Mangion, Ian K., Hettche, Frank, MacMillan, David W. C.

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