Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold von Hardcastle, Ian R, Ahmed, Shafiq U, Atkins, Helen, Farnie, Gillian, Golding, Bernard T, Griffin, Roger J, Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J, Kitching, Martin S, Newell, David R, Norbedo, Stefano, Northen, Julian S, Reid, Rebecca J, Saravanan, K, Willems, Henriëtte M. G, Lunec, John

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Isoindolinone-based inhibitors of the MDM2–p53 protein–protein interaction von Hardcastle, Ian R., Ahmed, Shafiq U., Atkins, Helen, Calvert, A. Hilary, Curtin, Nicola J., Farnie, Gillian, Golding, Bernard T., Griffin, Roger J., Guyenne, Sabrina, Hutton, Claire, Källblad, Per, Kemp, Stuart J., Kitching, Martin S., Newell, David R., Norbedo, Stefano, Northen, Julian S., Reid, Rebecca J., Saravanan, K., Willems, Henriëtte M.G., Lunec, John

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Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated SN2 reactivity of 2,2,2-trifluoroethoxysulfonates von Wong, Christopher, Griffin, Roger J, Hardcastle, Ian R, Northen, Julian S, Wang, Lan-Zhen, Golding, Bernard T

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Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone von Malik, Vatsala, Zhang, Meng, Dover, Lynn G, Northen, Julian S, Flinn, Anthony, Perry, Justin J, Black, Gary W

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Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity von Thomas, Huw D, Saravanan, Kappusamy, Wang, Lan-Zhen, Lin, Mei-Ju, Northen, Julian S, Barlow, Hannah, Barton, Marion, Newell, David R, Griffin, Roger J, Golding, Bernard T, Curtin, Nicola J

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Stereoselective alpha-fluoroamide and alpha-fluoro-gamma-lactone synthesis by an asymmetric zwitterionic aza-Claisen rearrangement von Tenza, Kenny, Northen, Julian S, O'Hagan, David, Slawin, Alexandra M Z

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Antineoplastic agents. 529. Isolation and structure of nootkastatins 1 and 2 from the Alaskan yellow cedar Chamaecyparis nootkatensis von Pettit, G.R, Tan, R, Northen, J.S, Herald, D.L, Chapuis, J.C, Pettit, R.K

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Process Development toward a Pro-Drug of Buprenorphine von Berrell, Sophie L, Byard, Stephen J, Carey, John S, Codina, Antonio, Davis, J. Alf, Filer, Katherine, Garnett, Alasdair, Marshall, Robin, Martin, Stephen J, Mykytiuk, John, Northen, Julian, Pandya, Urvish, Reid, Gary, Smyth, Catherine, Watson, Lesa

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Antineoplastic Agents. 529. Isolation and Structure of Nootkastatins 1 and 2 from the Alaskan Yellow Cedar Chamaecyparis n ootkatensis von Pettit, George R, Tan, Rui, Northen, Julian S, Herald, Delbert L, Chapuis, Jean-Charles, Pettit, Robin K

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The role of organic fluorine in directing alkylation reactions via lithium chelation von Tenza, Kenny, Northen, Julian S., O’Hagan, David, Slawin, Alexandra M.Z.

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Nucleoside Transport Inhibitors: Structure−Activity Relationships for Pyrimido[5,4- d ]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of α 1 -Acid G... von Saravanan, Kappusamy, Barlow, Hannah C., Barton, Marion, Calvert, A. Hilary, Golding, Bernard T., Newell, David R., Northen, Julian S., Curtin, Nicola J., Thomas, Huw D., Griffin, Roger J.

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Parallel kinetic resolution of active esters using designer oxazolidin-2-ones derived from phenylglycine von Chavda, Sameer, Coulbeck, Elliot, Dingjan, Marco, Eames, Jason, Flinn, Anthony, Northen, Julian

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Efficient parallel resolution of an active ester of 2-phenylpropionic acid using quasi-enantiomeric Evans’ oxazolidinones von Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Flinn, Anthony, Northen, Julian, Yohannes, Yonas

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SALTS OF 2-BROMOLYSERGIC ACID DIETHYLAMIDE von NORTHEN, Julian S, MOORE, Gillian

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Catalytic phosphorylation using a bifunctional imidazole derived nucleophilic catalyst von Jones, Simon, Northen, Julian, Rolfe, Alan

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Controlled stepwise conversion of 2,4,6,8-tetrachloropyrimido[5,4-d]pyrimidine into 2,4,6,8-tetrasubstituted pyrimido[5,4-d]pyrimidines

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PKC INHIBITOR SOLID STATE FORMS von OLMSTEAD, Kay, NORTHEN, Julian

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Nucleoside Transport Inhibitors: Structure−Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of α1-Acid Glyco... von Saravanan, Kappusamy, Barlow, Hannah C, Barton, Marion, Calvert, A. Hilary, Golding, Bernard T, Newell, David R, Northen, Julian S, Curtin, Nicola J, Thomas, Huw D, Griffin, Roger J

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Efficient Parallel Resolution of Racemic Evans’ Oxazolidinones Using quasi-Enantiomeric Profens von Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Flinn, Anthony, Motevalli, Majid, Northen, Julian, Yohannes, Yonas

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CRYSTALLINE HYDROBROMIDE SALT OF 5-MEO-DMT von PARKER, Jake, NORTHEN, Julian, MOORE, Gillian

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