Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging von Gustafson, Jeffrey L., Neklesa, Taavi K., Cox, Carly S., Roth, Anke G., Buckley, Dennis L., Tae, Hyun Seop, Sundberg, Thomas B., Stagg, D. Blake, Hines, John, McDonnell, Donald P., Norris, John D., Crews, Craig M.

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Connections and Regulation of the Human Estrogen Receptor von McDonnell, Donald P., Norris, John D.

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Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells von Safi, Rachid, Wardell, Suzanne E., Watkinson, Paige, Qin, Xiaodi, Lee, Marissa, Park, Sunghee, Krebs, Taylor, Dolan, Emma L., Blattler, Adam, Tsuji, Toshiya, Nayak, Surendra, Khater, Marwa, Fontanillo, Celia, Newlin, Madeline A., Kirkland, Megan L., Xie, Yingtian, Long, Henry, Fink, Emma C., Fanning, Sean W., Runyon, Scott, Brown, Myles, Xu, Shuichan, Owzar, Kouros, Norris, John D., McDonnell, Donald P.

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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer von Cocce, Kimberly J., Jasper, Jeff S., Desautels, Taylor K., Everett, Logan, Wardell, Suzanne, Westerling, Thomas, Baldi, Robert, Wright, Tricia M., Tavares, Kendall, Yllanes, Alex, Bae, Yeeun, Blitzer, Jeremy T., Logsdon, Craig, Rakiec, Daniel P., Ruddy, David A., Jiang, Tiancong, Broadwater, Gloria, Hyslop, Terry, Hall, Allison, Laine, Muriel, Phung, Linda, Greene, Geoffrey L., Martin, Lesley-Ann, Pancholi, Sunil, Dowsett, Mitch, Detre, Simone, Marks, Jeffrey R., Crawford, Gregory E., Brown, Myles, Norris, John D., Chang, Ching-yi, McDonnell, Donald P.

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Structural Basis for an Unexpected Mode of SERM-Mediated ER Antagonism von Wu, Ya-Ling, Yang, Xiaojing, Ren, Zhong, McDonnell, Donald P., Norris, John D., Willson, Timothy M., Greene, Geoffrey L.

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CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC von Stice, James P, Wardell, Suzanne E, Norris, John D, Yllanes, Alexander P, Alley, Holly M, Haney, Victoria O, White, Hannah S, Safi, Rachid, Winter, Peter S, Cocce, Kimberly J, Kishton, Rigel J, Lawrence, Scott A, Strum, Jay C, McDonnell, Donald P

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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer von Tria, George S, Abrams, Tinya, Baird, Jason, Burks, Heather E, Firestone, Brant, Gaither, L. Alex, Hamann, Lawrence G, He, Guo, Kirby, Christina A, Kim, Sunkyu, Lombardo, Franco, Macchi, Kaitlin J, McDonnell, Donald P, Mishina, Yuji, Norris, John D, Nunez, Jill, Springer, Clayton, Sun, Yingchuan, Thomsen, Noel M, Wang, Chunrong, Wang, Jianling, Yu, Bing, Tiong-Yip, Choi-Lai, Peukert, Stefan

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HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer von Johng, Dorhyun, Torga, Gonzalo, Ewing, Charles M., Jin, Kideok, Norris, John D., McDonnell, Donald P., Isaacs, William B.

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Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumo... von Wardell, Suzanne E., Yllanes, Alexander P., Chao, Christina A., Bae, Yeeun, Andreano, Kaitlyn J., Desautels, Taylor K., Heetderks, Kendall A., Blitzer, Jeremy T., Norris, John D., McDonnell, Donald P.

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G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer von Andreano, Kaitlyn J., Wardell, Suzanne E., Baker, Jennifer G., Desautels, Taylor K., Baldi, Robert, Chao, Christina A., Heetderks, Kendall A., Bae, Yeeun, Xiong, Rui, Tonetti, Debra A., Gutgesell, Lauren M., Zhao, Jiong, Sorrentino, Jessica A., Thompson, Delita A., Bisi, John E., Strum, Jay C., Thatcher, Gregory R. J., Norris, John D.

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Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer von Norris, John D, Ellison, Stephanie J, Baker, Jennifer G, Stagg, David B, Wardell, Suzanne E, Park, Sunghee, Alley, Holly M, Baldi, Robert M, Yllanes, Alexander, Andreano, Kaitlyn J, Stice, James P, Lawrence, Scott A, Eisner, Joel R, Price, Douglas K, Moore, William R, Figg, William D, McDonnell, Donald P

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Correction to: Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activ... von Wardell, Suzanne E., Yllanes, Alexander P., Chao, Christina A., Bae, Yeeun, Andreano, Kaitlyn J., Desautels, Taylor K., Heetderks, Kendall A., Blitzer, Jeremy T., Norris, John D., McDonnell, Donald P.

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Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer von Pollock, Julie A, Wardell, Suzanne E, Parent, Alexander A, Stagg, David B, Ellison, Stephanie J, Alley, Holly M, Chao, Christina A, Lawrence, Scott A, Stice, James P, Spasojevic, Ivan, Baker, Jennifer G, Kim, Sung Hoon, McDonnell, Donald P, Katzenellenbogen, John A, Norris, John D

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Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cells in Vitro von Frigo, Daniel E., Sherk, Andrea B., Wittmann, Bryan M., Norris, John D., Wang, Qianben, Joseph, James D., Toner, Aidan P., Brown, Myles, McDonnell, Donald P.

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Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β von Chang, Ching-yi, Norris, John D., Grøn, Hanne, Paige, Lisa A., Hamilton, Paul T., Kenan, Daniel J., Fowlkes, Dana, McDonnell, Donald P.

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Identification of a Third Autonomous Activation Domain within the Human Estrogen Receptor von Norris, John D, Fan, Daju, Kerner, Sandra A, McDonnell, Donald P

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Direct effects of the selective CYP17 lyase (L) inhibitor, VT-464, on the androgen receptor (AR) and its oral activity in an F876L tumor mouse xenograft model von Moore, William R., Norris, John D., Wardell, Suzanne, Eisner, Joel Robert, Hoekstra, William J., Schotzinger, Robert J., McDonnell, Donald P.

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A Negative Coregulator for the Human ER von Norris, John D, Fan, Daju, Sherk, Andrea, McDonnell, Donald P

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Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor von CONNOR, Caroline E, NORRIS, John D, BROADWATER, Gloria, WILLSON, Timothy M, GOTTARDIS, Marco M, DEWHIRST, Mark W, MCDONNELL, Donald P

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The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor von Wagner, Brandee L., Norris, John D., Knotts, Trina A., Weigel, Nancy L., McDonnell, Donald P.

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