The cellular thermal shift assay for evaluating drug target interactions in cells von Jafari, Rozbeh, Almqvist, Helena, Axelsson, Hanna, Ignatushchenko, Marina, Lundbäck, Thomas, Nordlund, Pär, Molina, Daniel Martinez

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The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies von Martinez Molina, Daniel, Nordlund, Pär

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Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay von Molina, Daniel Martinez, Jafari, Rozbeh, Ignatushchenko, Marina, Seki, Takahiro, Larsson, E. Andreas, Dan, Chen, Sreekumar, Lekshmy, Cao, Yihai, Nordlund, Pär

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Modulation of Protein-Interaction States through the Cell Cycle von Dai, Lingyun, Zhao, Tianyun, Bisteau, Xavier, Sun, Wendi, Prabhu, Nayana, Lim, Yan Ting, Sobota, Radoslaw M., Kaldis, Philipp, Nordlund, Pär

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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil von Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär

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Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA) von Dai, Lingyun, Prabhu, Nayana, Yu, Liang Ying, Bacanu, Smaranda, Ramos, Anderson Daniel, Nordlund, Pär

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Tracking cancer drugs in living cells by thermal profiling of the proteome von Savitski, Mikhail M., Reinhard, Friedrich B. M., Franken, Holger, Werner, Thilo, Savitski, Maria Fälth, Eberhard, Dirk, Molina, Daniel Martinez, Jafari, Rozbeh, Dovega, Rebecca Bakszt, Klaeger, Susan, Kuster, Bernhard, Nordlund, Pär, Bantscheff, Marcus, Drewes, Gerard

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Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2 von Guettou, Fatma, Quistgaard, Esben M, Raba, Michael, Moberg, Per, Löw, Christian, Nordlund, Pär

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Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters von Quistgaard, Esben M, Löw, Christian, Moberg, Per, Trésaugues, Lionel, Nordlund, Pär

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Crystal Structure of a Divalent Metal Ion Transporter CorA at 2.9 Angstrom Resolution von Eshaghi, Said, Niegowski, Damian, Kohl, Andreas, Molina, Daniel Martinez, Lesley, Scott A, Nordlund, Pär

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An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions von Lim, Yan Ting, Prabhu, Nayana, Dai, Lingyun, Go, Ka Diam, Chen, Dan, Sreekumar, Lekshmy, Egeblad, Louise, Eriksson, Staffan, Chen, Liyan, Veerappan, Saranya, Teo, Hsiang Ling, Tan, Chris Soon Heng, Lengqvist, Johan, Larsson, Andreas, Sobota, Radoslaw M, Nordlund, Pär

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Chemical Screening Methods to Identify Ligands That Promote Protein Stability, Protein Crystallization, and Structure Determination von Vedadi, Masoud, Niesen, Frank H., Allali-Hassani, Abdellah, Fedorov, Oleg Y., Finerty, Patrick J., Wasney, Gregory A., Yeung, Ron, Arrowsmith, Cheryl, Ball, Linda J., Berglund, Helena, Hui, Raymond, Marsden, Brian D., Nordlund, Pär, Sundstrom, Michael, Weigelt, Johan, Edwards, Aled M.

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Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization von Dealwis, Chris Godfrey, Fairman, James Wesley, Wijerathna, Sanath Ranjan, Ahmad, Md Faiz, Xu, Hai, Nakano, Ryo, Jha, Shalini, Prendergast, Jay, Welin, R Martin, Flodin, Susanne, Roos, Annette, Nordlund, Pär, Li, Zongli, Walz, Thomas

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Target identification and validation of natural products with label-free methodology: A critical review from 2005 to 2020 von Dai, Lingyun, Li, Zhijie, Chen, Dan, Jia, Lin, Guo, Jinan, Zhao, Tianyun, Nordlund, Pär

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Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell von Asial, Ignacio, Cheng, Yue Xiang, Engman, Henrik, Dollhopf, Maria, Wu, Binghuang, Nordlund, Pär, Cornvik, Tobias

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Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases von Trésaugues, Lionel, Silvander, Camilla, Flodin, Susanne, Welin, Martin, Nyman, Tomas, Gräslund, Susanne, Hammarström, Martin, Berglund, Helena, Nordlund, Pär

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The Crystal Structure of the Human Toll-like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer von Nyman, Tomas, Stenmark, Pål, Flodin, Susanne, Johansson, Ida, Hammarström, Martin, Nordlund, Pär

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IMPRINTS.CETSA and IMPRINTS.CETSA.app: an R package and a Shiny application for the analysis and interpretation of IMPRINTS-CETSA data von Gerault, Marc-Antoine, Granjeaud, Samuel, Camoin, Luc, Nordlund, Pär, Dai, Lingyun

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Deep learning based CETSA feature prediction cross multiple cell lines with latent space representation von Zhao, Shenghao, Yang, Xulei, Zeng, Zeng, Qian, Peisheng, Zhao, Ziyuan, Dai, Lingyun, Prabhu, Nayana, Nordlund, Pär, Tam, Wai Leong

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The Radical Site in Chlamydial Ribonucleotide Reductase Defines a New R2 Subclass von Högbom, Martin, Stenmark, Pål, Voevodskaya, Nina, McClarty, Grant, Gräslund, Astrid, Nordlund, Pär

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