M2 tumor-associated macrophages play important role in predicting response to neoadjuvant chemotherapy in triple-negative breast carcinoma von Arole, Vidya, Nitta, Hiroaki, Wei, Lai, Shen, Tiansheng, Parwani, Anil V., Li, Zaibo

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Predictive significance of HER2 intratumoral heterogeneity, determined by simultaneous gene and protein analysis, for resistance to trastuzumab-based treatments for HER2-positive b... von Horii, Rie, Nitta, Hiroaki, Nojima, Masanori, Maruyama, Reo, Ueno, Takayuki, Ito, Yoshinori, Ohno, Shinji, Banks, Peter, Kanda, Hiroaki, Akiyama, Futoshi

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HER2 intratumoral heterogeneity is independently associated with distal metastasis and overall survival in HER2-positive breast carcinomas von Shen, Tiansheng, Nitta, Hiroaki, Wei, Lai, Parwani, Anil V., Li, Zaibo

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The assessment of HER2 status in breast cancer: the past, the present, and the future von Nitta, Hiroaki, Kelly, Brian D., Allred, Craig, Jewell, Suzan, Banks, Peter, Dennis, Eslie, Grogan, Thomas M.

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Intratumoral Estrogen Receptor Heterogeneity of Expression in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer as Evaluated by a Brightfield Multiplex Assay von Masuda, Shinobu, Nitta, Hiroaki, Kelly, Brian D., Zhang, Wenjun, Farrell, Michael, Dennis, Eslie

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Artificial intelligence reveals features associated with breast cancer neoadjuvant chemotherapy responses from multi-stain histopathologic images von Huang, Zhi, Shao, Wei, Han, Zhi, Alkashash, Ahmad Mahmoud, De la Sancha, Carlo, Parwani, Anil V., Nitta, Hiroaki, Hou, Yanjun, Wang, Tongxin, Salama, Paul, Rizkalla, Maher, Zhang, Jie, Huang, Kun, Li, Zaibo

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Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer von Wesolowski, Robert, Stiff, Andrew, Quiroga, Dionisia, McQuinn, Christopher, Li, Zaibo, Nitta, Hiroaki, Savardekar, Himanshu, Benner, Brooke, Ramaswamy, Bhuvaneswari, Lustberg, Maryam, Layman, Rachel M, Macrae, Erin, Kassem, Mahmoud, Williams, Nicole, Sardesai, Sagar, VanDeusen, Jeffrey, Stover, Daniel, Cherian, Mathew, Mace, Thomas A, Yu, Lianbo, Duggan, Megan, Carson, 3rd, William E

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A novel gene–protein assay for evaluating HER2 status in gastric cancer: simultaneous analyses of HER2 protein overexpression and gene amplification reveal intratumoral heterogenei... von Nishida, Yasunori, Kuwata, Takeshi, Nitta, Hiroaki, Dennis, Eslie, Aizawa, Masaki, Kinoshita, Takahiro, Ohtsu, Atsushi, Ochiai, Atsushi

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Bright-Field Dual-Color Chromogenic In Situ Hybridization for Diagnosing Echinoderm Microtubule-Associated Protein-Like 4-Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinomas von Yoshida, Akihiko, Tsuta, Koji, Nitta, Hiroaki, Hatanaka, Yutaka, Asamura, Hisao, Sekine, Ikuo, Grogan, Thomas M., Fukayama, Masashi, Shibata, Tatsuhiro, Furuta, Koh, Kohno, Takashi, Tsuda, Hitoshi

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Gene copy number gain of EGFR is a poor prognostic biomarker in gastric cancer: evaluation of 855 patients with bright-field dual in situ hybridization (DISH) method von Higaki, Eiji, Kuwata, Takeshi, Nagatsuma, Akiko Kawano, Nishida, Yasunori, Kinoshita, Takahiro, Aizawa, Masaki, Nitta, Hiroaki, Nagino, Masato, Ochiai, Atsushi

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Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma von STASIK, Christopher J, NITTA, Hiroaki, GROGAN, Thomas M, RIMSZA, Lisa M, WENJUN ZHANG, MOSHER, Charles H, COOK, James R, TUBBS, Raymond R, UNGER, Joseph M, BROOKS, Tracy A, PERSKY, Daniel O, WILKINSON, Sarah T

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A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the HER2 gene, and chromosome 17 centromere (CEN17) in... von Nitta, Hiroaki, Kelly, Brian D, Padilla, Mary, Wick, Nikolaus, Brunhoeber, Patrick, Bai, Isaac, Singh, Shalini, Ranger-Moore, Jim, Bieniarz, Chris, Tsuda, Hitoshi, Grogan, Thomas M

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Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma von Allo, Ghassan, Bandarchi, Bizhan, Yanagawa, Naoki, Wang, Ami, Shih, Warren, Xu, Jing, Dalby, Morgan, Nitta, Hiroaki, To, Christine, Liu, Ni, Sykes, Jenna, Tsao, Ming S

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HER2 Intratumoral Heterogeneity in Breast Cancer, an Evolving Concept von Hou, Yanjun, Nitta, Hiroaki, Li, Zaibo

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New Methods for ALK Status Diagnosis in Non–Small-Cell Lung Cancer: An Improved ALK Immunohistochemical Assay and a New, Brightfield, Dual ALK IHC–In Situ Hybridization Assay von Nitta, Hiroaki, Tsuta, Koji, Yoshida, Akihiko, Ho, Steffan N., Kelly, Brian D., Murata, Lauren B., Kosmeder, Jerry, White, Katie, Ehser, Sandra, Towne, Penny, Schemp, Crystal, McElhinny, Abigail, Ranger-Moore, Jim, Bieniarz, Chris, Singh, Shalini, Tsuda, Hitoshi, Grogan, Thomas M.

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Development of automated brightfield double in situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay perform... von Nitta, Hiroaki, Hauss-Wegrzyniak, Beatrice, Lehrkamp, Megan, Murillo, Adrian E, Gaire, Fabien, Farrell, Michael, Walk, Eric, Penault-Llorca, Frederique, Kurosumi, Masafumi, Dietel, Manfred, Wang, Lin, Loftus, Margaret, Pettay, James, Tubbs, Raymond R, Grogan, Thomas M

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Chromogenic Tissue-Based Methods for Detection of Gene Amplifications (or Rearrangements) Combined with Protein Overexpression in Clinical Samples von Nitta, Hiroaki, Kelly, Brian

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Insulin-like growth factor-1 receptor protein expression and gene copy number alterations in non–small cell lung carcinomas von Tsuta, Koji, MD, PhD, Mimae, Takahiro, MD, Nitta, Hiroaki, PhD, Yoshida, Akihiko, MD, PhD, Maeshima, Akiko M., MD, PhD, Asamura, Hisao, MD, PhD, Grogan, Thomas M., MD, Furuta, Koh, MD, PhD, Tsuda, Hitoshi, MD, PhD

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Automated brightfield break-apart in situ hybridization (ba-ISH) application: ALK and MALT1 genes as models von Nitta, Hiroaki, Zhang, Wenjun, Kelly, Brian D., Miller, Melanie, Pestic-Dragovich, Lidija, Bieniarz, Christopher, Vasicek, Thomas J., Marafioti, Teresa, Rimsza, Lisa, Grogan, Thomas M.

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The pre-B-cell receptor associated protein VpreB3 is a useful diagnostic marker for identifying c-MYC translocated lymphomas von RODIG, Scott J, KUTOK, Jeffery L, BEN-NERIAH, Susana, FARINHA, Pedro, SHIPP, Margaret A, PIRIS, Miguel A, GROGAN, Thomas M, PILERI, Stefano A, GASCOYNE, Randy D, MARAFIOTI, Teresa, PATERSON, Jennifer C, NITTA, Hiroaki, WENJUN ZHANG, CHAPUY, Bjoern, TUMWINE, Lynette K, MONTES-MORENO, Santiago, AGOSTINELLI, Claudio, JOHNSON, Nathalie A

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