B7-H3 Negatively Modulates CTL-Mediated Cancer Immunity von Yonesaka, Kimio, Haratani, Koji, Takamura, Shiki, Sakai, Hitomi, Kato, Ryoji, Takegawa, Naoki, Takahama, Takayuki, Tanaka, Kaoru, Hayashi, Hidetoshi, Takeda, Masayuki, Kato, Sigeki, Maenishi, Osamu, Sakai, Kazuko, Chiba, Yasutaka, Okabe, Takafumi, Kudo, Keita, Hasegawa, Yoshikazu, Kaneda, Hiroyasu, Yamato, Michiko, Hirotani, Kenji, Miyazawa, Masaaki, Nishio, Kazuto, Nakagawa, Kazuhiko

Volltext

Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild‐type KRAS colorectal cancer‐WJOG 6210G von Shitara, Kohei, Yonesaka, Kimio, Denda, Tadamichi, Yamazaki, Kentaro, Moriwaki, Toshikazu, Tsuda, Masahiro, Takano, Toshimi, Okuda, Hiroyuki, Nishina, Tomohiro, Sakai, Kazuko, Nishio, Kazuto, Tokunaga, Shoji, Yamanaka, Takeharu, Boku, Narikazu, Hyodo, Ichinosuke, Muro, Kei

Volltext

LUX-Lung 4: A Phase II Trial of Afatinib in Patients With Advanced Non–Small-Cell Lung Cancer Who Progressed During Prior Treatment With Erlotinib, Gefitinib, or Both von KATAKAMI, Nobuyuki, ATAGI, Shinji, NISHIO, Kazuto, SEKI, Yoko, EBISAWA, Ryuichi, SHAHIDI, Mehdi, YAMAMOTO, Nobuyuki, GOTO, Koichi, HIDA, Toyoaki, HORAI, Takeshi, INOUE, Akira, ICHINOSE, Yukito, KOBOYASHI, Kunihiko, TAKEDA, Koji, KIURA, Katsuyuki

Volltext

Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer von Kobayashi, Yoshihisa, Azuma, Koichi, Nagai, Hiroki, Kim, Young Hak, Togashi, Yosuke, Sesumi, Yuichi, Chiba, Masato, Shimoji, Masaki, Sato, Katsuaki, Tomizawa, Kenji, Takemoto, Toshiki, Nishio, Kazuto, Mitsudomi, Tetsuya

Volltext

The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicine von Hatanaka, Yutaka, Kuwata, Takeshi, Morii, Eiichi, Kanai, Yae, Ichikawa, Hitoshi, Kubo, Takashi, Hatanaka, Kanako C., Sakai, Kazuko, Nishio, Kazuto, Fujii, Satoshi, Okamoto, Wataru, Yoshino, Takayuki, Ochiai, Atsushi, Oda, Yoshinao

Volltext

Mutational activation of the epidermal growth factor receptor down‐regulates major histocompatibility complex class I expression via the extracellular signal‐regulated kinase in no... von Watanabe, Satomi, Hayashi, Hidetoshi, Haratani, Koji, Shimizu, Shigeki, Tanizaki, Junko, Sakai, Kazuko, Kawakami, Hisato, Yonesaka, Kimio, Tsurutani, Junji, Togashi, Yosuke, Nishio, Kazuto, Ito, Akihiko, Nakagawa, Kazuhiko

Volltext

Real‐world study of next‐generation sequencing diagnostic biomarker testing for patients with lung cancer in Japan von Takahashi, Toshiaki, Nishio, Makoto, Nishino, Kazumi, Yoshiki, Yasumasa, Shiraiwa, Naoko, Emir, Birol, Iadeluca, Laura, Yatabe, Yasushi, Nishio, Kazuto

Volltext

An HER3-targeting antibody–drug conjugate incorporating a DNA topoisomerase I inhibitor U3-1402 conquers EGFR tyrosine kinase inhibitor-resistant NSCLC von Yonesaka, Kimio, Takegawa, Naoki, Watanabe, Satomi, Haratani, Koji, Kawakami, Hisato, Sakai, Kazuko, Chiba, Yasutaka, Maeda, Naoyuki, Kagari, Takashi, Hirotani, Kenji, Nishio, Kazuto, Nakagawa, Kazuhiko

Volltext

Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts von Kato, Ryoji, Haratani, Koji, Hayashi, Hidetoshi, Sakai, Kazuko, Sakai, Hitomi, Kawakami, Hisato, Tanaka, Kaoru, Takeda, Masayuki, Yonesaka, Kimio, Nishio, Kazuto, Nakagawa, Kazuhiko

Volltext

HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non-Small Cell Lung Cancer von Yonesaka, Kimio, Tanizaki, Junko, Maenishi, Osamu, Haratani, Koji, Kawakami, Hisato, Tanaka, Kaoru, Hayashi, Hidetoshi, Sakai, Kazuko, Chiba, Yasutaka, Tsuya, Asuka, Goto, Hiroki, Otsuka, Eri, Okida, Hiroaki, Kobayashi, Maki, Yoshimoto, Ryoto, Funabashi, Masanori, Hashimoto, Yuuri, Hirotani, Kenji, Kagari, Takashi, Nishio, Kazuto, Nakagawa, Kazuhiko

Volltext

Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor von Kimura, Hideharu, Sakai, Kazuko, Arao, Tokuzo, Shimoyama, Tatsu, Tamura, Tomohide, Nishio, Kazuto

Volltext

Multiplex gene‐panel testing for lung cancer patients von Yatabe, Yasushi, Sunami, Kuniko, Goto, Koichi, Nishio, Kazuto, Aragane, Naoko, Ikeda, Sadakatsu, Inoue, Akira, Kinoshita, Ichiro, Kimura, Hideharu, Sakamoto, Tomohiro, Satouchi, Miyako, Shimizu, Junichi, Tsuta, Koji, Toyooka, Shinichi, Nishino, Kazumi, Hatanaka, Yutaka, Matsumoto, Shingo, Mikubo, Masashi, Yokose, Tomoyuki, Dosaka‐Akita, Hirotoshi

Volltext

Exploration of resistance mechanisms for epidermal growth factor receptor‐tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next‐generati... von Iwama, Eiji, Sakai, Kazuko, Azuma, Koichi, Harada, Daijiro, Nosaki, Kaname, Hotta, Katsuyuki, Nishio, Makoto, Kurata, Takayasu, Fukuhara, Tatsuro, Akamatsu, Hiroaki, Goto, Koichi, Shimose, Takayuki, Kishimoto, Junji, Nakanishi, Yoichi, Nishio, Kazuto, Okamoto, Isamu

Volltext

Tocilizumab, a proposed therapy for the cachexia of Interleukin6-expressing lung cancer von Ando, Katsutoshi, Takahashi, Fumiyuki, Kato, Motoyasu, Kaneko, Norihiro, Doi, Tokuhide, Ohe, Yuichiro, Koizumi, Fumiaki, Nishio, Kazuto, Takahashi, Kazuhisa

Volltext

Role of ERK-BIM and STAT3-Survivin Signaling Pathways in ALK Inhibitor-Induced Apoptosis in EML4-ALK-Positive Lung Cancer von TAKEZAWA, Ken, OKAMOTO, Isamu, NISHIO, Kazuto, JÄNNE, Pasi A, NAKAGAWA, Kazuhiko

Volltext

Detection of epidermal growth factor receptor T790M mutation in plasma DNA from patients refractory to epidermal growth factor receptor tyrosine kinase inhibitor von Sakai, Kazuko, Horiike, Atsushi, Irwin, Darryl L., Kudo, Keita, Fujita, Yoshihiko, Tanimoto, Azusa, Sakatani, Toshio, Saito, Ryota, Kaburaki, Kyohei, Yanagitani, Noriko, Ohyanagi, Fumiyoshi, Nishio, Makoto, Nishio, Kazuto

Volltext

Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA von Sunami, Kuniko, Bando, Hideaki, Yatabe, Yasushi, Naito, Yoichi, Takahashi, Hideaki, Tsuchihara, Katsuya, Toyooka, Shinichi, Mimori, Koshi, Kohsaka, Shinji, Uetake, Hiroyuki, Kinoshita, Ichiro, Komine, Keigo, Takeda, Masayuki, Hayashida, Tetsu, Tamura, Kenji, Nishio, Kazuto, Yamamoto, Noboru

Volltext

Detection of Epidermal Growth Factor Receptor Mutations in Serum as a Predictor of the Response to Gefitinib in Patients with Non–Small-Cell Lung Cancer von Kimura, Hideharu, Kasahara, Kazuo, Kawaishi, Makoto, Kunitoh, Hideo, Tamura, Tomohide, Holloway, Brian, Nishio, Kazuto

Volltext

Liquid biopsy-based comprehensive gene mutation profiling for gynecological cancer using CAncer Personalized Profiling by deep Sequencing von Iwahashi, Naoyuki, Sakai, Kazuko, Noguchi, Tomoko, Yahata, Tamaki, Matsukawa, Hitomi, Toujima, Saori, Nishio, Kazuto, Ino, Kazuhiko

Volltext

Performance of Oncomine Fusion Transcript kit for formalin‐fixed, paraffin‐embedded lung cancer specimens von Sakai, Kazuko, Ohira, Tatsuo, Matsubayashi, Jun, Yoneshige, Azusa, Ito, Akihiko, Mitsudomi, Tetsuya, Nagao, Toshitaka, Iwamatsu, Emi, Katayama, Jin, Ikeda, Norihiko, Nishio, Kazuto

Volltext