Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas von TANIGUCHI, Kazuya, UCHIDA, Junji, NISHINO, Kazumi, KUMAGAI, Toru, OKUYAMA, Takako, OKAMI, Jiro, HIGASHIYAMA, Masahiko, KODAMA, Ken, IMAMURA, Fumio, KATO, Kikuya

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Metastatic site as a predictor of nivolumab efficacy in patients with advanced non-small cell lung cancer: A retrospective multicenter trial von Tamiya, Motohiro, Tamiya, Akihiro, Inoue, Takako, Kimura, Madoka, Kunimasa, Kei, Nakahama, Kenji, Taniguchi, Yoshihiko, Shiroyama, Takayuki, Isa, Shun-Ichi, Nishino, Kazumi, Kumagai, Toru, Suzuki, Hidekazu, Hirashima, Tomonori, Atagi, Shinji, Imamura, Fumio

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Proteasome Inhibition Overcomes ALK-TKI Resistance in ALK-Rearranged/TP53-Mutant NSCLC via Noxa Expression von Tanimoto, Azusa, Matsumoto, Shingo, Takeuchi, Shinji, Arai, Sachiko, Fukuda, Koji, Nishiyama, Akihiro, Yoh, Kiyotaka, Ikeda, Takaya, Furuya, Naoki, Nishino, Kazumi, Ohe, Yuichiro, Goto, Koichi, Yano, Seiji

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Multiplex gene‐panel testing for lung cancer patients von Yatabe, Yasushi, Sunami, Kuniko, Goto, Koichi, Nishio, Kazuto, Aragane, Naoko, Ikeda, Sadakatsu, Inoue, Akira, Kinoshita, Ichiro, Kimura, Hideharu, Sakamoto, Tomohiro, Satouchi, Miyako, Shimizu, Junichi, Tsuta, Koji, Toyooka, Shinichi, Nishino, Kazumi, Hatanaka, Yutaka, Matsumoto, Shingo, Mikubo, Masashi, Yokose, Tomoyuki, Dosaka‐Akita, Hirotoshi

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A Large-Scale Prospective Concordance Study of Plasma- and Tissue-Based Next-Generation Targeted Sequencing for Advanced Non-Small Cell Lung Cancer (LC-SCRUM-Liquid) von Sugimoto, Akira, Matsumoto, Shingo, Udagawa, Hibiki, Itotani, Ryo, Usui, Yuko, Umemura, Shigeki, Nishino, Kazumi, Nakachi, Ichiro, Kuyama, Shoichi, Daga, Haruko, Hara, Satoshi, Miyamoto, Shingo, Kato, Terufumi, Sakakibara-Konishi, Jun, Tabata, Eriko, Nakagawa, Taku, Kawaguchi, Tomoya, Sakai, Tetsuya, Shibata, Yuji, Izumi, Hiroki, Nosaki, Kaname, Zenke, Yoshitaka, Yoh, Kiyotaka, Goto, Koichi

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Real‐world study of next‐generation sequencing diagnostic biomarker testing for patients with lung cancer in Japan von Takahashi, Toshiaki, Nishio, Makoto, Nishino, Kazumi, Yoshiki, Yasumasa, Shiraiwa, Naoko, Emir, Birol, Iadeluca, Laura, Yatabe, Yasushi, Nishio, Kazuto

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Diagnostic Accuracy of Noninvasive Genotyping of EGFR in Lung Cancer Patients by Deep Sequencing of Plasma Cell-Free DNA von Uchida, Junji, Kato, Kikuya, Kukita, Yoji, Kumagai, Toru, Nishino, Kazumi, Daga, Haruko, Nagatomo, Izumi, Inoue, Takako, Kimura, Madoka, Oba, Shigeyuki, Ito, Yuri, Takeda, Koji, Imamura, Fumio

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The ratio of T790M to EGFR-activating mutation predicts response of osimertinib in 1st or 2nd generation EGFR-TKI-refractory NSCLC von Tamiya, Motohiro, Tamiya, Akihiro, Okamoto, Norio, Taniguchi, Yoshihiko, Nishino, Kazumi, Atagi, Shinji, Hirashima, Tomonori, Imamura, Fumio, Kumagai, Toru, Suzuki, Hidekazu

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The CLIP1–LTK fusion is an oncogenic driver in non‐small‐cell lung cancer von Izumi, Hiroki, Matsumoto, Shingo, Liu, Jie, Tanaka, Kosuke, Mori, Shunta, Hayashi, Kumiko, Kumagai, Shogo, Shibata, Yuji, Hayashida, Takuma, Watanabe, Kana, Fukuhara, Tatsuro, Ikeda, Takaya, Yoh, Kiyotaka, Kato, Terufumi, Nishino, Kazumi, Nakamura, Atsushi, Nakachi, Ichiro, Kuyama, Shoichi, Furuya, Naoki, Sakakibara-Konishi, Jun, Okamoto, Isamu, Taima, Kageaki, Ebi, Noriyuki, Daga, Haruko, Yamasaki, Akira, Kodani, Masahiro, Udagawa, Hibiki, Kirita, Keisuke, Zenke, Yoshitaka, Nosaki, Kaname, Sugiyama, Eri, Sakai, Tetsuya, Nakai, Tokiko, Ishii, Genichiro, Niho, Seiji, Ohtsu, Atsushi, Kobayashi, Susumu S., Goto, Koichi

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Monitoring of treatment responses and clonal evolution of tumor cells by circulating tumor DNA of heterogeneous mutant EGFR genes in lung cancer von Imamura, Fumio, Uchida, Junji, Kukita, Yoji, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Oba, Shigeyuki, Kato, Kikuya

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Fragment size and dynamics of EGFR-mutated tumor-derived DNA provide prognostic information regarding EGFR-TKI efficacy in patients with EGFR-mutated NSCLC von Kunimasa, Kei, Nishino, Kazumi, Sato, Yoshiharu, Mori, Masahide, Ihara, Shoichi, Suzuki, Hidekazu, Nagatomo, Izumi, Kumagai, Toru, Morishima, Toshitaka, Imamura, Fumio

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Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment von Uchida, Junji, Imamura, Fumio, Kukita, Yoji, Oba, Shigeyuki, Kumagai, Toru, Nishino, Kazumi, Inoue, Takako, Kimura, Madoka, Kato, Kikuya

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Quantitative identification of mutant alleles derived from lung cancer in plasma cell-free DNA via anomaly detection using deep sequencing data von Kukita, Yoji, Uchida, Junji, Oba, Shigeyuki, Nishino, Kazumi, Kumagai, Toru, Taniguchi, Kazuya, Okuyama, Takako, Imamura, Fumio, Kato, Kikuya

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Results of the non-small cell lung cancer part of a phase III, open-label, randomized trial evaluating topical corticosteroid therapy for facial acneiform dermatitis induced by EGF... von Nishino, Kazumi, Fujiwara, Yutaka, Ohe, Yuichiro, Saito, Ryota, Miyauchi, Eisaku, Kobayashi, Tetsu, Nakai, Yasuo, Takahashi, Toshiaki, Shibata, Taro, Hamaguchi, Tetsuya, Kikuchi, Katsuko, Yamazaki, Naoya, Fukuda, Haruhiko, Nozawa, Keiko, Kiyohara, Yoshio

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Different spatial distributions of brain metastases from lung cancer by histological subtype and mutation status of epidermal growth factor receptor von Takano, Koji, Kinoshita, Manabu, Takagaki, Masatoshi, Sakai, Mio, Tateishi, Souichirou, Achiha, Takamune, Hirayama, Ryuichi, Nishino, Kazumi, Uchida, Junji, Kumagai, Toru, Okami, Jiro, Kawaguchi, Atsushi, Hashimoto, Naoya, Nakanishi, Katsuyuki, Imamura, Fumio, Higashiyama, Masahiko, Yoshimine, Toshiki

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Overall survival analysis of patients enrolled in a randomized phase III trial comparing gefitinib and erlotinib for previously treated advanced lung adenocarcinoma (WJOG5108LFS) von Katakami, Nobuyuki, Yokoyama, Toshihide, Morita, Satoshi, Okamoto, Tatsuro, Urata, Yoshiko, Hattori, Yoshihiro, Iwamoto, Yasuo, Sato, Yuki, Ikeda, Norihiko, Takahashi, Toshiaki, Daga, Haruko, Oguri, Tetsuya, Fujisaka, Yasuhito, Nishino, Kazumi, Sugawara, Shunichi, Kozuki, Toshiyuki, Oki, Masahide, Yamamoto, Nobuyuki, Nakagawa, Kazuhiko

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Manual route modification using an oblique method following automatic virtual bronchoscopic navigation von Inoue, Takako, Kawamura, Takahisa, Kunimasa, Kei, Tamiya, Motohiro, Kuhara, Hanako, Nishino, Kazumi, Odani, Satomi, Imamura, Fumio, Kumagai, Toru, Miyake, Kotaro

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Exceptionally long‐lasting response to dabrafenib plus trametinib treatment in a patient with lung adenocarcinoma harboring the BRAF V600E mutation with high expression of PD‐L1: A... von Inoue, Takako, Kunimasa, Kei, Tamiya, Motohiro, Kawamura, Takahisa, Minami, Toshiyuki, Nishino, Kazumi

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Biomarker testing for personalized, first-line therapy in advanced nonsquamous non-small cell lung cancer patients in the real world setting in Japan: a retrospective, multicenter,... von Shimizu, Junichi, Masago, Katsuhiro, Saito, Haruhiro, Nishino, Kazumi, Kurata, Takayasu, Itoh, Yohji, Yoshimura, Yoko, Yabuki, Yutaka, Dosaka-Akita, Hirotoshi

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Genetic dissection of intratumor heterogeneity of PD‐L1 expression in EGFR‐mutated lung adenocarcinoma von Kunimasa, Kei, Hirotsu, Yosuke, Amemiya, Kenji, Honma, Keiichiro, Nakamura, Harumi, Nishino, Kazumi, Omata, Masao

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