Structures and mechanisms of CRISPR RNA-guided effector nucleases von Nishimasu, Hiroshi, Nureki, Osamu

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Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 von Hirano, Seiichi, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Nureki, Osamu

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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1 von Yamano, Takashi, Zetsche, Bernd, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Engineered CRISPR-Cas9 nuclease with expanded targeting space von Nishimasu, Hiroshi, Shi, Xi, Ishiguro, Soh, Gao, Linyi, Hirano, Seiichi, Okazaki, Sae, Noda, Taichi, Abudayyeh, Omar O, Gootenberg, Jonathan S, Mori, Hideto, Oura, Seiya, Holmes, Benjamin, Tanaka, Mamoru, Seki, Motoaki, Hirano, Hisato, Aburatani, Hiroyuki, Ishitani, Ryuichiro, Ikawa, Masahito, Yachie, Nozomu, Zhang, Feng, Nureki, Osamu

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Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain von Song, Myungjae, Lim, Jung Min, Min, Seonwoo, Oh, Jeong-Seok, Kim, Dong Young, Woo, Jae-Sung, Nishimasu, Hiroshi, Cho, Sung-Rae, Yoon, Sungroh, Kim, Hyongbum Henry

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Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 von Kato, Kazuki, Nishimasu, Hiroshi, Oikawa, Daisuke, Hirano, Seiichi, Hirano, Hisato, Kasuya, Go, Ishitani, Ryuichiro, Tokunaga, Fuminori, Nureki, Osamu

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Amplification-free RNA detection with CRISPR–Cas13 von Shinoda, Hajime, Taguchi, Yuya, Nakagawa, Ryoya, Makino, Asami, Okazaki, Sae, Nakano, Masahiro, Muramoto, Yukiko, Takahashi, Chiharu, Takahashi, Ikuko, Ando, Jun, Noda, Takeshi, Nureki, Osamu, Nishimasu, Hiroshi, Watanabe, Rikiya

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Structure of the miniature type V-F CRISPR-Cas effector enzyme von Takeda, Satoru N., Nakagawa, Ryoya, Okazaki, Sae, Hirano, Hisato, Kobayashi, Kan, Kusakizako, Tsukasa, Nishizawa, Tomohiro, Yamashita, Keitaro, Nishimasu, Hiroshi, Nureki, Osamu

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Base editors for simultaneous introduction of C-to-T and A-to-G mutations von Sakata, Rina C., Ishiguro, Soh, Mori, Hideto, Tanaka, Mamoru, Tatsuno, Kenji, Ueda, Hiroki, Yamamoto, Shogo, Seki, Motoaki, Masuyama, Nanami, Nishida, Keiji, Nishimasu, Hiroshi, Arakawa, Kazuharu, Kondo, Akihiko, Nureki, Osamu, Tomita, Masaru, Aburatani, Hiroyuki, Yachie, Nozomu

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Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1 von Nishimasu, Hiroshi, Yamano, Takashi, Gao, Linyi, Zhang, Feng, Ishitani, Ryuichiro, Nureki, Osamu

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Structure of the Dicer-2–R2D2 heterodimer bound to a small RNA duplex von Yamaguchi, Sonomi, Naganuma, Masahiro, Nishizawa, Tomohiro, Kusakizako, Tsukasa, Tomari, Yukihide, Nishimasu, Hiroshi, Nureki, Osamu

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Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 von Hirano, Seiichi, Abudayyeh, Omar O., Gootenberg, Jonathan S., Horii, Takuro, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Structure and Engineering of Francisella novicida Cas9 von Hirano, Hisato, Gootenberg, Jonathan S., Horii, Takuro, Abudayyeh, Omar O., Kimura, Mika, Hsu, Patrick D., Nakane, Takanori, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy von Shibata, Mikihiro, Nishimasu, Hiroshi, Kodera, Noriyuki, Hirano, Seiichi, Ando, Toshio, Uchihashi, Takayuki, Nureki, Osamu

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Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex von Kato, Kazuki, Zhou, Wenyuan, Okazaki, Sae, Isayama, Yukari, Nishizawa, Tomohiro, Gootenberg, Jonathan S., Abudayyeh, Omar O., Nishimasu, Hiroshi

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Crystal structure of Drosophila Piwi von Yamaguchi, Sonomi, Oe, Akira, Nishida, Kazumichi M., Yamashita, Keitaro, Kajiya, Asako, Hirano, Seiichi, Matsumoto, Naoki, Dohmae, Naoshi, Ishitani, Ryuichiro, Saito, Kuniaki, Siomi, Haruhiko, Nishimasu, Hiroshi, Siomi, Mikiko C., Nureki, Osamu

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Structure and function of Zucchini endoribonuclease in piRNA biogenesis von Nishimasu, Hiroshi, Ishizu, Hirotsugu, Saito, Kuniaki, Fukuhara, Satoshi, Kamatani, Miharu K., Bonnefond, Luc, Matsumoto, Naoki, Nishizawa, Tomohiro, Nakanaga, Keita, Aoki, Junken, Ishitani, Ryuichiro, Siomi, Haruhiko, Siomi, Mikiko C., Nureki, Osamu

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Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA von Matsumoto, Naoki, Nishimasu, Hiroshi, Sakakibara, Kazuhiro, Nishida, Kazumichi M., Hirano, Takamasa, Ishitani, Ryuichiro, Siomi, Haruhiko, Siomi, Mikiko C., Nureki, Osamu

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RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease von Kato, Kazuki, Okazaki, Sae, Schmitt-Ulms, Cian, Jiang, Kaiyi, Zhou, Wenyuan, Ishikawa, Junichiro, Isayama, Yukari, Adachi, Shungo, Nishizawa, Tomohiro, Makarova, Kira S, Koonin, Eugene V, Abudayyeh, Omar O, Gootenberg, Jonathan S, Nishimasu, Hiroshi

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Structure and engineering of the minimal type VI CRISPR-Cas13bt3 von Nakagawa, Ryoya, Kannan, Soumya, Altae-Tran, Han, Takeda, Satoru N, Tomita, Atsuhiro, Hirano, Hisato, Kusakizako, Tsukasa, Nishizawa, Tomohiro, Yamashita, Keitaro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu

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