Mutual exclusivity analysis identifies oncogenic network modules von Ciriello, Giovanni, Cerami, Ethan, Sander, Chris, Schultz, Nikolaus

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Genome-wide analysis of noncoding regulatory mutations in cancer von Weinhold, Nils, Jacobsen, Anders, Schultz, Nikolaus, Sander, Chris, Lee, William

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Emerging landscape of oncogenic signatures across human cancers von Ciriello, Giovanni, Miller, Martin L, Aksoy, Bülent Arman, Senbabaoglu, Yasin, Schultz, Nikolaus, Sander, Chris

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The expanding landscape of ‘oncohistone’ mutations in human cancers von Nacev, Benjamin A., Feng, Lijuan, Bagert, John D., Lemiesz, Agata E., Gao, JianJiong, Soshnev, Alexey A., Kundra, Ritika, Schultz, Nikolaus, Muir, Tom W., Allis, C. David

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Genomic correlates of clinical outcome in advanced prostate cancer von Abida, Wassim, Cyrta, Joanna, Heller, Glenn, Prandi, Davide, Armenia, Joshua, Coleman, Ilsa, Cieslik, Marcin, Benelli, Matteo, Robinson, Dan, Van Allen, Eliezer M., Sboner, Andrea, Fedrizzi, Tarcisio, Mosquera, Juan Miguel, Robinson, Brian D., De Sarkar, Navonil, Kunju, Lakshmi P., Tomlins, Scott, Wu, Yi Mi, Rodrigues, Daniel Nava, Loda, Massimo, Gopalan, Anuradha, Reuter, Victor E., Pritchard, Colin C., Mateo, Joaquin, Bianchini, Diletta, Miranda, Susana, Carreira, Suzanne, Rescigno, Pasquale, Filipenko, Julie, Vinson, Jacob, Montgomery, Robert B., Beltran, Himisha, Heath, Elisabeth I., Scher, Howard I., Kantoff, Philip W., Taplin, Mary-Ellen, Schultz, Nikolaus, deBono, Johann S., Demichelis, Francesca, Nelson, Peter S., Rubin, Mark A., Chinnaiyan, Arul M., Sawyers, Charles L.

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Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway von Li, Zhiqiang, Razavi, Pedram, Li, Qing, Toy, Weiyi, Liu, Bo, Ping, Christina, Hsieh, Wilson, Sanchez-Vega, Francisco, Brown, David N., Da Cruz Paula, Arnaud F., Morris, Luc, Selenica, Pier, Eichenberger, Emily, Shen, Ronglai, Schultz, Nikolaus, Rosen, Neal, Scaltriti, Maurizio, Brogi, Edi, Baselga, Jose, Reis-Filho, Jorge S., Chandarlapaty, Sarat

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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers von Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A, Shah, Ronak H, Dogan, Snjezana, Ricarte-Filho, Julio C, Krishnamoorthy, Gnana P, Xu, Bin, Schultz, Nikolaus, Berger, Michael F, Sander, Chris, Taylor, Barry S, Ghossein, Ronald, Ganly, Ian, Fagin, James A

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The long tail of oncogenic drivers in prostate cancer von Armenia, Joshua, Wankowicz, Stephanie A. M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.

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Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies von Harding, James J, Nandakumar, Subhiksha, Armenia, Joshua, Khalil, Danny N, Albano, Melanie, Ly, Michele, Shia, Jinru, Hechtman, Jaclyn F, Kundra, Ritika, El Dika, Imane, Do, Richard K, Sun, Yichao, Kingham, T Peter, D'Angelica, Michael I, Berger, Michael F, Hyman, David M, Jarnagin, William, Klimstra, David S, Janjigian, Yelena Y, Solit, David B, Schultz, Nikolaus, Abou-Alfa, Ghassan K

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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity von Chang, Matthew T, Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H, Chapman, Jocelyn S, Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D, Solit, David B, Olshen, Adam B, Schultz, Nikolaus, Taylor, Barry S

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal von Gao, Jianjiong, Aksoy, Bülent Arman, Dogrusoz, Ugur, Dresdner, Gideon, Gross, Benjamin, Sumer, S Onur, Sun, Yichao, Jacobsen, Anders, Sinha, Rileen, Larsson, Erik, Cerami, Ethan, Sander, Chris, Schultz, Nikolaus

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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention von Lowery, Maeve A, Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F, Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E, O'Reilly, Eileen M, El-Dika, Imane, Jarnagin, William R, Harding, James J, D'Angelica, Michael I, Cercek, Andrea, Hechtman, Jaclyn F, Solit, David B, Schultz, Nikolaus, Hyman, David M, Klimstra, David S, Saltz, Leonard B, Abou-Alfa, Ghassan K

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The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers von Razavi, Pedram, Chang, Matthew T., Xu, Guotai, Bandlamudi, Chaitanya, Ross, Dara S., Vasan, Neil, Cai, Yanyan, Bielski, Craig M., Donoghue, Mark T.A., Jonsson, Philip, Penson, Alexander, Shen, Ronglai, Pareja, Fresia, Kundra, Ritika, Middha, Sumit, Cheng, Michael L., Zehir, Ahmet, Kandoth, Cyriac, Patel, Ruchi, Huberman, Kety, Smyth, Lillian M., Jhaveri, Komal, Modi, Shanu, Traina, Tiffany A., Dang, Chau, Zhang, Wen, Weigelt, Britta, Li, Bob T., Ladanyi, Marc, Hyman, David M., Schultz, Nikolaus, Robson, Mark E., Hudis, Clifford, Brogi, Edi, Viale, Agnes, Norton, Larry, Dickler, Maura N., Berger, Michael F., Iacobuzio-Donahue, Christine A., Chandarlapaty, Sarat, Scaltriti, Maurizio, Reis-Filho, Jorge S., Solit, David B., Taylor, Barry S., Baselga, José

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Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer von Dalin, Martin G, Desrichard, Alexis, Katabi, Nora, Makarov, Vladimir, Walsh, Logan A, Lee, Ken-Wing, Wang, Qingguo, Armenia, Joshua, West, Lyndsay, Dogan, Snjezana, Wang, Lu, Ramaswami, Deepa, Ho, Alan L, Ganly, Ian, Solit, David B, Berger, Michael F, Schultz, Nikolaus D, Reis-Filho, Jorge S, Chan, Timothy A, Morris, Luc G T

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Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer von Yaeger, Rona, Chatila, Walid K., Lipsyc, Marla D., Hechtman, Jaclyn F., Cercek, Andrea, Sanchez-Vega, Francisco, Jayakumaran, Gowtham, Middha, Sumit, Zehir, Ahmet, Donoghue, Mark T.A., You, Daoqi, Viale, Agnes, Kemeny, Nancy, Segal, Neil H., Stadler, Zsofia K., Varghese, Anna M., Kundra, Ritika, Gao, Jianjiong, Syed, Aijazuddin, Hyman, David M., Vakiani, Efsevia, Rosen, Neal, Taylor, Barry S., Ladanyi, Marc, Berger, Michael F., Solit, David B., Shia, Jinru, Saltz, Leonard, Schultz, Nikolaus

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Next-generation Sequencing of Nonmuscle Invasive Bladder Cancer Reveals Potential Biomarkers and Rational Therapeutic Targets von Pietzak, Eugene J, Bagrodia, Aditya, Cha, Eugene K, Drill, Esther N, Iyer, Gopa, Isharwal, Sumit, Ostrovnaya, Irina, Baez, Priscilla, Li, Qiang, Berger, Michael F, Zehir, Ahmet, Schultz, Nikolaus, Rosenberg, Jonathan E, Bajorin, Dean F, Dalbagni, Guido, Al-Ahmadie, Hikmat, Solit, David B, Bochner, Bernard H

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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial von Janjigian, Yelena Y, Maron, Steven B, Chatila, Walid K, Millang, Brittanie, Chavan, Shweta S, Alterman, Carly, Chou, Joanne F, Segal, Michal F, Simmons, Marc Z, Momtaz, Parisa, Shcherba, Marina, Ku, Geoffrey Y, Zervoudakis, Alice, Won, Elizabeth S, Kelsen, David P, Ilson, David H, Nagy, Rebecca J, Lanman, Richard B, Ptashkin, Ryan N, Donoghue, Mark T A, Capanu, Marinela, Taylor, Barry S, Solit, David B, Schultz, Nikolaus, Hechtman, Jaclyn F

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Pattern discovery and cancer gene identification in integrated cancer genomic data von Mo, Qianxing, Wang, Sijian, Seshan, Venkatraman E., Olshen, Adam B., Schultz, Nikolaus, Sander, Chris, Powers, R. Scott, Ladanyi, Marc, Shen, Ronglai

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Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection von Park, Wungki, Chen, Jiapeng, Chou, Joanne F, Varghese, Anna M, Yu, Kenneth H, Wong, Winston, Capanu, Marinela, Balachandran, Vinod, McIntyre, Caitlin A, El Dika, Imane, Khalil, Danny N, Harding, James J, Ghalehsari, Nima, McKinnell, Zoe, Chalasani, Sree B, Makarov, Vladimir, Selenica, Pier, Pei, Xin, Lecomte, Nicolas, Kelsen, David P, Abou-Alfa, Ghassan K, Robson, Mark E, Zhang, Liying, Berger, Michael F, Schultz, Nikolaus, Chan, Timothy A, Powell, Simon N, Reis-Filho, Jorge S, Iacobuzio-Donahue, Christine A, Riaz, Nadeem, O'Reilly, Eileen M

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Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations von Babur, Özgün, Gönen, Mithat, Aksoy, Bülent Arman, Schultz, Nikolaus, Ciriello, Giovanni, Sander, Chris, Demir, Emek

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