Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia: interim analysis of the STOP 2G-TKI study von Rea, Delphine, Nicolini, Franck E., Tulliez, Michel, Guilhot, François, Guilhot, Joelle, Guerci-Bresler, Agnès, Gardembas, Martine, Coiteux, Valérie, Guillerm, Gaelle, Legros, Laurence, Etienne, Gabriel, Pignon, Jean-Michel, Villemagne, Bruno, Escoffre-Barbe, Martine, Ianotto, Jean-Christophe, Charbonnier, Aude, Johnson-Ansah, Hyacinthe, Noel, Marie-Pierre, Rousselot, Philippe, Mahon, François-Xavier

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Longer treatment duration and history of osteoarticular symptoms predispose to tyrosine kinase inhibitor withdrawal syndrome von Berger, Marc G., Pereira, Bruno, Rousselot, Philippe, Cony‐Makhoul, Pascale, Gardembas, Martine, Legros, Laurence, Escoffre‐Barbe, Martine, Nicolini, Franck‐Emmanuel, Saugues, Sandrine, Lambert, Céline, Réa, Delphine, Guerci‐Bresler, Agnès, Giraudier, Stéphane, Guilhot, Joëlle, Saussele, Susanne, Mahon, François‐Xavier

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Immature CML cells implement a BMP autocrine loop to escape TKI treatment von Grockowiak, Elodie, Laperrousaz, Bastien, Jeanpierre, Sandrine, Voeltzel, Thibault, Guyot, Boris, Gobert, Stéphanie, Nicolini, Franck E., Maguer-Satta, Véronique

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Loss of Major Molecular Response As a Trigger for Restarting Tyrosine Kinase Inhibitor Therapy in Patients With Chronic-Phase Chronic Myelogenous Leukemia Who Have Stopped Imatinib... von ROUSSELOT, Philippe, CHARBONNIER, Aude, ESCOFFRE-BARBE, Martine, GUERCI-BRESLER, Agnès, TULLIEZ, Michel, PROST, Stéphane, SPENTCHIAN, Marc, CAYUELA, Jean Michel, REIFFERS, Josy, CHOMEL, Jean Claude, TURHAN, Ali, GUILHOT, Joëlle, CONY-MAKHOUL, Pascale, GUILHOT, François, MAHON, François-Xavier, AGAPE, Philippe, NICOLINI, Franck E, VARET, Bruno, GARDEMBAS, Martine, ETIENNE, Gabriel, REA, Delphine, ROY, Lydia

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Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION) von Kantarjian, Hagop M., Shah, Neil P., Cortes, Jorge E., Baccarani, Michele, Agarwal, Mohan B., Undurraga, María Soledad, Wang, Jianxiang, Kassack Ipiña, Juan Julio, Kim, Dong-Wook, Ogura, Michinori, Pavlovsky, Carolina, Junghanss, Christian, Milone, Jorge H., Nicolini, Franck E., Robak, Tadeusz, Van Droogenbroeck, Jan, Vellenga, Edo, Bradley-Garelik, M. Brigid, Zhu, Chao, Hochhaus, Andreas

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BCR::ABL1 digital PCR for treatment‐free remission prediction in chronic myeloid leukemia patients: An individual participant data meta‐analysis von Kockerols, Camille, Valk, Peter J. M., Dulucq, Stéphanie, Nicolini, Franck‐Emmanuel, Mahon, François‐Xavier, Atallah, Ehab, Mauro, Michael J., Radich, Jerald P., Bernardi, Simona, Russo, Domenico, Farina, Mirko, Mori, Silvia, Gambacorti‐Passerini, Carlo, Civettini, Ivan, Lu, Liu, Yeung, David, Branford, Susan, Colafigli, Gioia, Breccia, Massimo, Hogenbirk, Pauline, Rosmalen, Joost, Cornelissen, Jan J., Westerweel, Peter E.

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Dasatinib dose optimisation based on therapeutic drug monitoring reduces pleural effusion rates in chronic myeloid leukaemia patients von Rousselot, Philippe, Mollica, Luigina, Guilhot, Joëlle, Guerci, Agnès, Nicolini, Franck E., Etienne, Gabriel, Legros, Laurence, Charbonnier, Aude, Coiteux, Valérie, Dartigeas, Caroline, Escoffre‐Barbe, Martine, Roy, Lydia, Cony-Makhoul, Pascale, Dubruille, Viviane, Gardembas, Martine, Huguet, Françoise, Réa, Delphine, Cayssials, Emilie, Guilhot, François, Bergeron, Anne, Molimard, Mathieu, Mahon, Francois-Xavier, Cayuela, Jean-Michel, Busque, Lambert, Bouchet, Stéphane

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Stability Analysis of a Model of Interaction Between the Immune System and Cancer Cells in Chronic Myelogenous Leukemia von Besse, Apollos, Clapp, Geoffrey D., Bernard, Samuel, Nicolini, Franck E., Levy, Doron, Lepoutre, Thomas

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BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European Leu... von Soverini, Simona, Hochhaus, Andreas, Nicolini, Franck E., Gruber, Franz, Lange, Thoralf, Saglio, Giuseppe, Pane, Fabrizio, Müller, Martin C., Ernst, Thomas, Rosti, Gianantonio, Porkka, Kimmo, Baccarani, Michele, Cross, Nicholas C.P., Martinelli, Giovanni

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Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival von Hamilton, Ashley, Helgason, G. Vignir, Schemionek, Mirle, Zhang, Bin, Myssina, Svetlana, Allan, Elaine K., Nicolini, Franck E., Müller-Tidow, Carsten, Bhatia, Ravi, Brunton, Valerie G., Koschmieder, Steffen, Holyoake, Tessa L.

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Ponatinib evaluation and safety in real-life chronic myelogenous leukemia patients failing more than two tyrosine kinase inhibitors: the PEARL observational study von Heiblig, Maël, Rea, Delphine, Chrétien, Marie-Lorraine, Charbonnier, Aude, Rousselot, Philippe, Coiteux, Valérie, Escoffre-Barbe, Martine, Dubruille, Viviane, Huguet, Françoise, Cayssials, Emilie, Hermet, Eric, Guerci-Bresler, Agnès, Amé, Shanti, Sackmann-Sala, Lucila, Roy, Lydia, Sobh, Mohamad, Morisset, Stéphane, Etienne, Gabriel, Nicolini, Franck E.

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Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imat... von Mahon, François-Xavier, Prof, Réa, Delphine, MD, Guilhot, Joëlle, PhD, Guilhot, François, Prof, Huguet, Françoise, MD, Nicolini, Franck, MD, Legros, Laurence, MD, Charbonnier, Aude, MD, Guerci, Agnès, MD, Varet, Bruno, Prof, Etienne, Gabriel, MD, Reiffers, Josy, Prof, Rousselot, Philippe, Prof

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The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission von Jeanpierre, Sandrine, Arizkane, Kawtar, Thongjuea, Supat, Grockowiak, Elodie, Geistlich, Kevin, Barral, Lea, Voeltzel, Thibault, Guillemin, Anissa, Gonin-Giraud, Sandrine, Gandrillon, Olivier, Nicolini, Franck-Emmanuel, Mead, Adam J, Maguer-Satta, Véronique, Lefort, Sylvain

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Are there new relevant therapeutic endpoints in the modern era of the BCR::ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia? von Kantarjian, Hagop, Branford, Susan, Breccia, Massimo, Cortes, Jorge, Haddad, Fadi G., Hochhaus, Andreas, Hughes, Timothy, Issa, Ghayas C., Jabbour, Elias, Nicolini, Franck E., Sasaki, Koji, Xavier-Mahon, Francois

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Implications of BCR-ABL1 kinase domain-mediated resistance in chronic myeloid leukemia von Soverini, Simona, Branford, Susan, Nicolini, Franck E, Talpaz, Moshe, Deininger, Michael W.N, Martinelli, Giovanni, Müller, Martin C, Radich, Jerald P, Shah, Neil P

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Results of ponatinib as frontline therapy for chronic myeloid leukemia in chronic phase von Haddad, Fadi G., Sasaki, Koji, Nasr, Lewis, Short, Nicholas J., Kadia, Tapan, Dellasala, Sara, Cortes, Jorge, Nicolini, Franck E., Issa, Ghayas C., Jabbour, Elias, Kantarjian, Hagop

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A Multicenter Retrospective Chart Review Study of Treatment and Disease Patterns and Clinical Outcomes of Patients with Chronic-Phase Chronic Myeloid Leukemia in Third-Line Treatme... von Nicolini, Franck-Emmanuel, Huguet, Françoise, Huynh, Lynn, Xu, Churong, Bouvier, Christophe, Yocolly, Aurore, Etienne, Gabriel

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Second tyrosine kinase inhibitor discontinuation attempt in patients with chronic myeloid leukemia von Legros, Laurence, Nicolini, Franck E., Etienne, Gabriel, Rousselot, Philippe, Rea, Delphine, Giraudier, Stéphane, Guerci‐Bresler, Agnès, Huguet, Françoise, Gardembas, Martine, Escoffre, Martine, Ianotto, Jean‐Christophe, Noël, Marie‐Pierre, Varet, Bruno R., Pagliardini, Thomas, Touitou, Irit, Morisset, Stéphane, Mahon, Francois‐Xavier

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Bone marrow niche-derived extracellular matrix-degrading enzymes influence the progression of B-cell acute lymphoblastic leukemia von Verma, Divij, Zanetti, Costanza, Godavarthy, Parimala Sonika, Kumar, Rahul, Minciacchi, Valentina R., Pfeiffer, Jakob, Metzler, Markus, Lefort, Sylvain, Maguer-Satta, Véronique, Nicolini, Franck E., Burroni, Barbara, Fontenay, Michaela, Krause, Daniela S.

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Ponatinib after failure of second‐generation tyrosine kinase inhibitor in resistant chronic‐phase chronic myeloid leukemia von Kantarjian, Hagop M., Jabbour, Elias, Deininger, Michael, Abruzzese, Elisabetta, Apperley, Jane, Cortes, Jorge, Chuah, Charles, DeAngelo, Daniel J., DiPersio, John, Hochhaus, Andreas, Lipton, Jeffrey, Nicolini, Franck E., Pinilla‐Ibarz, Javier, Rea, Delphine, Rosti, Gianantonio, Rousselot, Philippe, Shah, Neil P., Talpaz, Moshe, Srivastava, Shouryadeep, Ren, Xiaowei, Mauro, Michael

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