Widespread and tissue specific age-related DNA methylation changes in mice von Maegawa, Shinji, Hinkal, George, Kim, Hyun Soo, Shen, Lanlan, Zhang, Li, Zhang, Jiexin, Zhang, Nianxiang, Liang, Shoudan, Donehower, Lawrence A, Issa, Jean-Pierre J

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Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 von Agrawal, Nishant, Frederick, Mitchell J., Pickering, Curtis R., Bettegowda, Chetan, Chang, Kyle, Li, Ryan J., Fakhry, Carole, Xie, Tong-Xin, Zhang, Jiexin, Wang, Jing, Zhang, Nianxiang, El-Naggar, Adel K., Jasser, Samar A., Weinstein, John N., Treviño, Lisa, Drummond, Jennifer A., Muzny, Donna M., Wu, Yuanqing, Wood, Laura D., Hruban, Ralph H., Westra, William H., Koch, Wayne M., Califano, Joseph A., Gibbs, Richard A., Sidransky, David, Vogelstein, Bert, Velculescu, Victor E., Papadopoulos, Nickolas, Wheeler, David A., Kinzler, Kenneth W., Myers, Jeffrey N.

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Prognostic impact and targeting of CRM1 in acute myeloid leukemia von Kojima, Kensuke, Kornblau, Steven M., Ruvolo, Vivian, Dilip, Archana, Duvvuri, Seshagiri, Davis, R. Eric, Zhang, Min, Wang, Zhiqiang, Coombes, Kevin R., Zhang, Nianxiang, Qiu, Yi Hua, Burks, Jared K., Kantarjian, Hagop, Shacham, Sharon, Kauffman, Michael, Andreeff, Michael

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Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia von Shojaee, Seyedmehdi, Caeser, Rebecca, Buchner, Maike, Park, Eugene, Swaminathan, Srividya, Hurtz, Christian, Geng, Huimin, Chan, Lai N., Klemm, Lars, Hofmann, Wolf-Karsten, Qiu, Yi Hua, Zhang, Nianxiang, Coombes, Kevin R., Paietta, Elisabeth, Molkentin, Jeffery, Koeffler, H. Phillip, Willman, Cheryl L., Hunger, Stephen P., Melnick, Ari, Kornblau, Steven M., Müschen, Markus

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Highly Phosphorylated FOXO3A Is an Adverse Prognostic Factor in Acute Myeloid Leukemia von KORNBLAU, Steven M, SINGH, Neera, YIHUA QIU, WENJING CHEN, NIANXIANG ZHANG, COOMBES, Kevin R

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Mechanisms of resistance to decitabine in the myelodysplastic syndrome von Qin, Taichun, Castoro, Ryan, El Ahdab, Samih, Jelinek, Jaroslav, Wang, Xiaodan, Si, Jiali, Shu, Jingmin, He, Rong, Zhang, Nianxiang, Chung, Woonbok, Kantarjian, Hagop M, Issa, Jean-Pierre J

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Focal Adhesion Kinase as a Potential Target in AML and MDS von Carter, Bing Z, Mak, Po Yee, Wang, Xiangmeng, Yang, Hui, Garcia-Manero, Guillermo, Mak, Duncan H, Mu, Hong, Ruvolo, Vivian R, Qiu, Yihua, Coombes, Kevin, Zhang, Nianxiang, Ragon, Brittany, Weaver, David T, Pachter, Jonathan A, Kornblau, Steven, Andreeff, Michael

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Age-related epigenetic drift in the pathogenesis of MDS and AML von Maegawa, Shinji, Gough, Sheryl M, Watanabe-Okochi, Naoko, Lu, Yue, Zhang, Nianxiang, Castoro, Ryan J, Estecio, Marcos R H, Jelinek, Jaroslav, Liang, Shoudan, Kitamura, Toshio, Aplan, Peter D, Issa, Jean-Pierre J

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Survivin is highly expressed in CD34+38− leukemic stem/progenitor cells and predicts poor clinical outcomes in AML von Carter, Bing Z., Qiu, Yihua, Huang, Xuelin, Diao, Lixia, Zhang, Nianxiang, Coombes, Kevin R., Mak, Duncan H., Konopleva, Marina, Cortes, Jorge, Kantarjian, Hagop M., Mills, Gordon B., Andreeff, Michael, Kornblau, Steven M.

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Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia von Jelinek, Jaroslav, Gharibyan, Vazganush, Estecio, Marcos R H, Kondo, Kimie, He, Rong, Chung, Woonbok, Lu, Yue, Zhang, Nianxiang, Liang, Shoudan, Kantarjian, Hagop M, Cortes, Jorge E, Issa, Jean-Pierre J

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Development of a robust classifier for quality control of reverse-phase protein arrays von Ju, Zhenlin, Liu, Wenbin, Roebuck, Paul L, Siwak, Doris R, Zhang, Nianxiang, Lu, Yiling, Davies, Michael A, Akbani, Rehan, Weinstein, John N, Mills, Gordon B, Coombes, Kevin R

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Slow down to stay alive von Hua, Yingqi, Gorshkov, Kirill, Yang, Yanwen, Wang, Wenyi, Zhang, Nianxiang, Hughes, Dennis P. M.

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Proteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cells von Kornblau, Steven M, Qutub, Amina, Yao, Hui, York, Heather, Qiu, Yi Hua, Graber, David, Ravandi, Farhad, Cortes, Jorge, Andreeff, Michael, Zhang, Nianxiang, Coombes, Kevin R

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Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia von Kornblau, Steven M., Qiu, Yi Hua, Zhang, Nianxiang, Singh, Neera, Faderl, Stefan, Ferrajoli, Alessandra, York, Heather, Qutub, Amina A., Coombes, Kevin R., Watson, Dennis K.

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Reverse-Phase Protein Array Analysis to Identify Biomarker Proteins in Human Pancreatic Cancer von Huang, Yu-Jing, Frazier, Marsha L., Zhang, Nianxiang, Liu, Qian, Wei, Chongjuan

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Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway von Zhang, Nianxiang, Liu, Xiuping, Li, Lei, Legerski, Randy

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Slow Down to Stay Alive: HER4 Protects Against Cellular Stress and Confers Chemoresistance in Neuroblastoma von YINGQI HUA, GORSHKOV, Kirill, YANWEN YANG, WENYI WANG, NIANXIANG ZHANG, HUGHES, Dennis P. M

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The Pso4 mRNA Splicing and DNA Repair Complex Interacts with WRN for Processing of DNA Interstrand Cross-links von Zhang, Nianxiang, Kaur, Ramandeep, Lu, Xiaoyan, Shen, Xi, Li, Lei, Legerski, Randy J.

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Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML von Carter, Bing Z., Qiu, Yi Hua, Zhang, Nianxiang, Coombes, Kevin R., Mak, Duncan H., Thomas, Deborah A., Ravandi, Farhad, Kantarjian, Hagop M., Koller, Erich, Andreeff, Michael, Kornblau, Steven M.

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Suppression of Peutz-Jeghers Polyposis by Targeting Mammalian Target of Rapamycin Signaling von Wei, Chongjuan, Amos, Christopher I, Zhang, Nianxiang, Wang, Xiaopei, Rashid, Asif, Walker, Cheryl L, Behringer, Richard R, Frazier, Marsha L

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