Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737 von TAHIR, Stephen K, XIUFEN YANG, ROSENBERG, Saul H, TSE, Christin, ANDERSON, Mark G, MORGAN-LAPPE, Susan E, SARTHY, Aparna V, JUN CHEN, WARNER, Robert B, NG, Shi-Chung, FESIK, Stephen W, ELMORE, Steve W

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death von Muchmore, Steven W., Sattler, Michael, Liang, Heng, Meadows, Robert P., Harlan, John E., Yoon, Ho Sup, Nettesheim, David, Chang, Brian S., Thompson, Craig B., Wong, Sui-Lam, Ng, Shi-Chung, Fesik, Stephen W.

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Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification von Tooker, Patricia, Yen, Wan-Ching, Ng, Shi-Chung, Negro-Vilar, Andrès, Hermann, Thomas W

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Human Chk1 Expression Is Dispensable for Somatic Cell Death and Critical for Sustaining G2 DNA Damage Checkpoint von Chen, Zehan, Xiao, Zhan, Chen, Jun, Ng, Shi-Chung, Sowin, Thomas, Sham, Hing, Rosenberg, Saul, Fesik, Steve, Zhang, Haiying

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Survivin Enhances Aurora-B Kinase Activity and Localizes Aurora-B in Human Cells von Chen, Jun, Jin, Sha, Tahir, Stephen K., Zhang, Haichao, Liu, Xuesong, Sarthy, Aparna V., McGonigal, Thomas P., Liu, Zhihong, Rosenberg, Saul H., Ng, Shi-Chung

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Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients von Kim, Phillip, Liu, Xinjun, Lee, Tani, Liu, Limin, Barham, Robert, Kirkland, Richard, Leesman, Glen, Kuller, Anne, Ybarrondo, Belen, Ng, Shi-Chung, Singh, Sharat

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Identification of Chaulmoogric Acid as a Small Molecule Activator of Protein Phosphatase 5 von Cher, Charmian, Tremblay, Marie-Helene, Barber, Jack R, Chung Ng, Shi, Zhang, Bin

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NMR structure and mutagenesis of the FADD (Mort1) death-effector domain von Fesik, Stephen W, Eberstadt, Matthias, Huang, Baohua, Chen, Zehan, Meadows, Robert P, Ng, Shi-Chung, Zheng, Lixin, Lenardo, Michael J

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Down-regulation of Survivin by Antisense Oligonucleotides Increases Apoptosis, Inhibits Cytokinesis and Anchorage-Independent Growth von Chen, Jun, Wu, Wei, Tahir, Stephen K., Kroeger, Paul E., Rosenberg, Saul H., Cowsert, Lex M., Bennett, Frank, Krajewski, Stanislaw, Krajewska, Maryla, Welsh, Kate, Reed, John C., Ng, Shi-Chung

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Development of a high-throughput fluorescence polarization assay for Bcl-xL von Zhang, Haichao, Nimmer, Paul, Rosenberg, Saul H, Ng, Shi-Chung, Joseph, Mary

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Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms von Qian, Jie, Voorbach, Martin J, Huth, Jeffrey R, Coen, Michael L, Zhang, Haichao, Ng, Shi-Chung, Comess, Kenneth M, Petros, Andrew M, Rosenberg, Saul H, Warrior, Usha, Burns, David J

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Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent von Li, Qun, Woods, Keith W., Claiborne, Akiyo, Gwaltney, II, Stephen L., Barr, Kenneth J., Liu, Gang, Gehrke, Laura, Credo, R.Bruce, Hui, Yu Hua, Lee, Jang, Warner, Robert B., Kovar, Peter, Nukkala, Michael A., Zielinski, Nicolette A., Tahir, Stephen K., Fitzgerald, Michael, Kim, Ki H., Marsh, Kennan, Frost, David, Ng, Shi-Chung, Rosenberg, Saul, Sham, Hing L.

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Distinctive Roles of PHAP Proteins and Prothymosin-α in a Death Regulatory Pathway von Jiang, Xuejun, Kim, Hyun-Eui, Shu, Hongjun, Zhao, Yingming, Zhang, Haichao, Kofron, James, Donnelly, Jennifer, Burns, Dave, Ng, Shi-chung, Rosenberg, Saul, Wang, Xiaodong

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Enhanced Secretory Production of a Single-Chain Antibody Fragment from Bacillus subtilis by Coproduction of Molecular Chaperones von Wu, S C, Ye, R, Wu, X C, Ng, S C, Wong, S L

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Rapid Colchicine Competition-Binding Scintillation Proximity Assay Using Biotin-Labeled Tubulin von Tahir, Stephen K, Kovar, Peter, Rosenberg, Saul H, Ng, Shi-Chung

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Biological Activity of A-289099: An Orally Active Tubulin-binding Indolyloxazoline Derivative von Tahir, Stephen K, Nukkala, Michael A, Zielinski Mozny, Nicolette A, Credo, R Bruce, Warner, Robert B, Li, Qun, Woods, Keith W, Claiborne, Akiyo, Gwaltney, 2nd, Stephen L, Frost, David J, Sham, Hing L, Rosenberg, Saul H, Ng, Shi-Chung

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Novel One-Pot Total Syntheses of Deoxyvasicinone, Mackinazolinone, Isaindigotone, and Their Derivatives Promoted by Microwave Irradiation von Liu, Ji-Feng, Ye, Ping, Sprague, Kevin, Sargent, Katie, Yohannes, Daniel, Baldino, Carmen M, Wilson, Christopher J, Ng, Shi-Chung

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Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL von Bruncko, Milan, Oost, Thorsten K, Belli, Barbara A, Ding, Hong, Joseph, Mary K, Kunzer, Aaron, Martineau, Darlene, McClellan, William J, Mitten, Michael, Ng, Shi-Chung, Nimmer, Paul M, Oltersdorf, Tilman, Park, Cheol-Min, Petros, Andrew M, Shoemaker, Alexander R, Song, Xiaohong, Wang, Xilu, Wendt, Michael D, Zhang, Haichao, Fesik, Stephen W, Rosenberg, Saul H, Elmore, Steven W

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Downregulation of Akt1 Inhibits Anchorage-Independent Cell Growth and Induces Apoptosis in Cancer Cells von Liu, Xuesong, Shi, Yan, Han, Edward K.-H., Chen, Zehan, Rosenberg, Saul H., Giranda, Vincent L., Luo, Yan, Ng, Shi-Chung

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Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives von Gwaltney, Stephen L., O'Connor, Stephen J., Nelson, Lissa T.J., Sullivan, Gerard M., Imade, Hovis, Wang, Weibo, Hasvold, Lisa, Li, Qun, Cohen, Jerome, Gu, Wen-Zhen, Tahir, Stephen K., Bauch, Joy, Marsh, Kennan, Ng, Shi-Chung, Frost, David J., Zhang, Haiying, Muchmore, Steve, Jakob, Clarissa G., Stoll, Vincent, Hutchins, Charles, Rosenberg, Saul H., Sham, Hing L.

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