The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors von Ko, Tun Kiat, Chuah, Charles T H, Huang, John W J, Ng, King-Pan, Ong, S Tiong

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The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia von Ko, Tun Kiat, Chin, Hui San, Chuah, Charles T H, Huang, John W J, Ng, King-Pan, Khaw, Seong Lin, Huang, David C S, Ong, S Tiong

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An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia von Ko, Tun Kiat, Javed, Asif, Lee, Kian Leong, Pathiraja, Thushangi N., Liu, Xingliang, Malik, Simeen, Soh, Sheila Xinxuan, Heng, Xiu Ting, Takahashi, Naoto, Tan, Joanna H.J., Bhatia, Ravi, Khng, Alexis J., Chng, Wee-Joo, Sia, Yee Yen, Fruman, David A., Ng, King Pan, Chan, Zhu En, Xie, Kim Jiajing, Hoi, Qiangze, Chan, Cheryl Xueli, Teo, Audrey S.M., Velazquez Camacho, Oscar, Meah, Wee Yang, Khor, Chiea Chuen, Ong, Chin Thing J., Soon, Wei Jia W., Tan, Patrick, Ng, Pauline C., Chuah, Charles, Hillmer, Axel M., Ong, S. Tiong

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Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition von Ng, King Pan, Manjeri, Aditi, Lee, Kian Leong, Huang, Weijie, Tan, Soo Yong, Chuah, Charles T.H., Poellinger, Lorenz, Ong, S. Tiong

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The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as th... von Ng, King Pan, Manjeri, Aditi, Lee, Lin Ming, Chan, Zhu En, Tan, Chin Yee, Tan, Qiancheng Darren, Majeed, A'Qilah, Lee, Kian Leong, Chuah, Charles, Suda, Toshio, Ong, S Tiong

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Multiple Aromatic Side Chains within a Disordered Structure Are Critical for Transcription and Transforming Activity of EWS Family Oncoproteins von Ng, King Pan, Potikyan, Gary, Savene, Rupert O. V., Denny, Christopher T., Uversky, Vladimir N., Lee, Kevin A. W.

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RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct von Chau, Bess Ling, Ng, King Pan, Li, Kim K C, Lee, Kevin A.W.

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Rapid production of clinical‐grade SARS‐CoV‐2 specific T cells von Leung, Wing, Soh, Teck Guan, Linn, Yeh Ching, Low, Jenny Guek‐Hong, Loh, Jiashen, Chan, Marieta, Chng, Wee Joo, Koh, Liang Piu, Poon, Michelle Li‐Mei, Ng, King Pan, Kuick, Chik Hong, Tan, Thuan Tong, Tan, Lip Kun, Seng, Michaela Su‐fern

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Human Bone Xenografts: from Preclinical Testing for Regenerative Medicine to Modeling of Diseases von Chong, Mark Seow Khoon, Bao, Chaolemeng, Ng, King Pan, Lim, Jing, Chan, Jerry Kok Yen

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The RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell lines von Zhao, Yang, Li, Kim K. C., Ng, King Pan, Ng, Chi Ho, Lee, Kevin A. W.

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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer von Ng, King Pan, Hillmer, Axel M, Chuah, Charles T H, Juan, Wen Chun, Ko, Tun Kiat, Teo, Audrey S M, Ariyaratne, Pramila N, Takahashi, Naoto, Sawada, Kenichi, Fei, Yao, Soh, Sheila, Lee, Wah Heng, Huang, John W J, Allen, John C, Woo, Xing Yi, Nagarajan, Niranjan, Kumar, Vikrant, Thalamuthu, Anbupalam, Poh, Wan Ting, Ang, Ai Leen, Mya, Hae Tha, How, Gee Fung, Yang, Li Yi, Koh, Liang Piu, Chowbay, Balram, Chang, Chia-Tien, Nadarajan, Veera S, Chng, Wee Joo, Than, Hein, Lim, Lay Cheng, Goh, Yeow Tee, Zhang, Shenli, Poh, Dianne, Tan, Patrick, Seet, Ju-Ee, Ang, Mei-Kim, Chau, Noan-Minh, Ng, Quan-Sing, Tan, Daniel S W, Soda, Manabu, Isobe, Kazutoshi, Nöthen, Markus M, Wong, Tien Y, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Sung, Wing-Kin, Tan, Eng Huat, Yatabe, Yasushi, Mano, Hiroyuki, Soo, Ross A, Chin, Tan Min, Lim, Wan-Teck, Ruan, Yijun, Ong, S Tiong

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The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies von Yu, Mengge, Nah, Giselle Sek Suan, Krishnan, Vaidehi, Sulaimi, Fatin Nasha Bte, Ng, King Pan, Wang, Chuqi, Bhatt, Shruti, Chuah, Charles, Bergstrom, David E, Ong, S Tiong

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A phase I/II study of adoptive SARS-CoV-2-specific T cells in immunocompromised hosts with or at risk of severe COVID-19 infection von Seng, Michaela Su-fern, Ng, King Pan, Soh, Teck Guan, Tan, Thuan Tong, Chan, Marieta, Maiwald, Matthias, Tan, Lip Kun, Linn, Yeh Ching, Leung, Wing

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Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia von Ong, Kelly Ooi Kee, Mok, Michelle Meng Huang, Niibori-Nambu, Akiko, Du, Linsen, Yanagida, Masatoshi, Wang, Chelsia Qiuxia, Bahirvani, Avinash Govind, Chin, Desmond Wai Loon, Koh, Cai Ping, Ng, King Pan, Yamashita, Namiko, Jacob, Bindya, Yokomizo, Tomomasa, Takizawa, Hitoshi, Matsumura, Takayoshi, Suda, Toshio, Lau, Jie-ying Amelia, Tan, Tuan Zea, Mori, Seiichi, Yang, Henry, Iwasaki, Masayuki, Minami, Takashi, Asou, Norio, Sun, Qiao-Yang, Ding, Ling-Wen, Koeffler, H. Phillip, Tenen, Daniel G., Shimizu, Ritsuko, Yamamoto, Masayuki, Ito, Yoshiaki, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh, Chng, Wee Joo, Osato, Motomi

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PRMT5 is required for the maintenance of genomic integrity in hematopoietic stem cells von Tan, Darren, Chin, Desmond, Li, Ying, Ng, King Pan, Nakamura-Ishizu, Ayako, Yang, Henry, Suda, Toshio

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The BCL-2 Inhibitor ABT-199 Enhances Imatinib-Induced Cell Death In Chronic Phase CML Progenitors von Ko, Tun Kiat, Chuah, Charles, Huang, John, Ng, King-Pan, Ong, S. Tiong

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The BIM Deletion Polymorphism: A Paradigm Of a Permissive Interaction Between Germline and Acquired TKI Resistance Factors In Chronic Myeloid Leukemia von Ko, Tun Kiat, Chuah, Charles, Huang, John W.J., Ng, King-Pan, Ong, S. Tiong

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The Genomic and Epigenomic Landscapes of Blast Crisis Transformation in Chronic Myeloid Leukemia von Ong, S. Tiong, Pathiraja, Thushangi, Javed, Asif, Soh, Xin Xuan Sheila, Malik, Simeen, Tan, Joanna H.J., Ko, Tun Kiat, Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Ng, King Pan, Chng, Wee Joo, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel

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Functional Analysis of the CML Blast Crisis Transcriptome and Epigenome Using Crispr-CAS9 and Pharmacologic Approaches von Ko, Tun Kiat, Soh, Xin Xuan Sheila, Yu, Willie, Winter, Peter S., Pathiraja, Thushangi, Javed, Asif, Malik, Simeen, Tan, Joanna H.J., Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Chng, Wee Joo, Valent, Peter, Cerny-Reiterer, Sabine, Ng, King Pan, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel, Wood, Kris C., Rozen, Steve, Ong, S. Tiong

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Physiologic Hypoxia Promotes Maintenance of CML Stem Cells Despite Effective BCR-ABL Inhibition von Ng, King-Pan, Lee, Kian Leong, Huang, Weijie, Poellinger, Lorenz, Chuah, Charles, Ong, Sin Tiong

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