Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast von Scheel, Christina, Eaton, Elinor Ng, Li, Sophia Hsin-Jung, Chaffer, Christine L., Reinhardt, Ferenc, Kah, Kong-Jie, Bell, George, Guo, Wenjun, Rubin, Jeffrey, Richardson, Andrea L., Weinberg, Robert A.

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Distinct EMT programs control normal mammary stem cells and tumour-initiating cells von Ye, Xin, Tam, Wai Leong, Shibue, Tsukasa, Kaygusuz, Yasemin, Reinhardt, Ferenc, Ng Eaton, Elinor, Weinberg, Robert A.

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Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells von Kröger, Cornelia, Afeyan, Alexander, Mraz, Jasmin, Eaton, Elinor Ng, Reinhardt, Ferenc, Khodor, Yevgenia L., Thiru, Prathapan, Bierie, Brian, Ye, Xin, Burge, Christopher B., Weinberg, Robert A.

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Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity von LIAO, Mai-Jing, CHENG CHENG ZHANG, NG EATON, Elinor, LODISH, Harvey F, WEINBERG, Robert A, BEIYAN ZHOU, ZIMONJIC, Drazen B, MANI, Sendurai A, KABA, Megan, GIFFORD, Ann, REINHARDT, Ferenc, POPESCU, Nicholas C, WENJUN GUO

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Direct and Indirect Regulators of Epithelial-Mesenchymal Transition-Mediated Immunosuppression in Breast Carcinomas von Dongre, Anushka, Rashidian, Mohammad, Eaton, Elinor Ng, Reinhardt, Ferenc, Thiru, Prathapan, Zagorulya, Maria, Nepal, Sunita, Banaz, Tuba, Martner, Anna, Spranger, Stefani, Weinberg, Robert A

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Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts von Kojima, Yasushi, Acar, Ahmet, Eaton, Elinor Ng, Mellody, Kieran T, Scheel, Christina, Ben-Porath, Ittai, Onder, Tamer T, Wang, Zhigang C, Richardson, Andrea L, Weinberg, Robert A, Orimo, Akira

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MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis von Phadnis, Vaishnavi V., Snider, Jamie, Varadharajan, Venkateshwari, Ramachandiran, Iyappan, Deik, Amy A., Lai, Zon Weng, Kunchok, Tenzin, Eaton, Elinor Ng, Sebastiany, Carolin, Lyakisheva, Anna, Vaccaro, Kyle D., Allen, Juliet, Yao, Zhong, Wong, Victoria, Geng, Betty, Weiskopf, Kipp, Clish, Clary B., Brown, J. Mark, Stagljar, Igor, Weinberg, Robert A., Henry, Whitney S.

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hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization von Meyerson, Matthew, Counter, Christopher M, Eaton, Elinor Ng, Ellisen, Leif W, Steiner, Philipp, Caddle, Stephanie Dickinson, Ziaugra, Liuda, Beijersbergen, Roderick L, Davidoff, Michael J, Liu, Qingyun, Bacchetti, Silvia, Haber, Daniel A, Weinberg, Robert A

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SnoN and Ski Protooncoproteins Are Rapidly Degraded in Response to Transforming Growth Factor β Signaling von Sun, Yin, Liu, Xuedong, Ng-Eaton, Elinor, Lodish, Harvey F., Weinberg, Robert A.

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Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase von COUNTER, C. M, MEYERSON, M, EATON, E. N, ELLISEN, L. W, CADDLE, S. D, HABER, D. A, WEINBERG, R. A

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The catalytic subunit of yeast telomerase von Counter, C.M, Meyerson, M, Eaton, E.N, Weinberg, R.A

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A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages von Lu, Haihui, Clauser, Karl R., Tam, Wai Leong, Fröse, Julia, Ye, Xin, Eaton, Elinor Ng, Reinhardt, Ferenc, Donnenberg, Vera S., Bhargava, Rohit, Carr, Steven A., Weinberg, Robert A.

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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells von Mani, Sendurai A., Guo, Wenjun, Liao, Mai-Jing, Eaton, Elinor Ng, Ayyanan, Ayyakkannu, Zhou, Alicia Y., Brooks, Mary, Reinhard, Ferenc, Zhang, Cheng Cheng, Shipitsin, Michail, Campbell, Lauren L., Polyak, Kornelia, Brisken, Cathrin, Yang, Jing, Weinberg, Robert A.

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ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells von Lambert, Arthur W., Fiore, Christopher, Chutake, Yogesh, Verhaar, Elisha R., Strasser, Patrick C., Chen, Mei Wei, Farouq, Daneyal, Das, Sunny, Li, Xin, Eaton, Elinor Ng, Zhang, Yun, Liu Donaher, Joana, Engstrom, Ian, Reinhardt, Ferenc, Yuan, Bingbing, Gupta, Sumeet, Wollison, Bruce, Eaton, Matthew, Bierie, Brian, Carulli, John, Olson, Eric R., Guenther, Matthew G., Weinberg, Robert A.

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase von Vaziri, H, Dessain, S K, Ng Eaton, E, Imai, S I, Frye, R A, Pandita, T K, Guarente, L, Weinberg, R A

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Abstract A82: Direct and indirect regulators of epithelial-to-mesenchymal transition mediated immunosuppression in breast carcinomas von Dongre, Anushka, Rashidian, Mohammad, Eaton, Elinor Ng, Reinhardt, Ferenc, Nepal, Sunita, Ploegh, Hidde, Weinberg, Robert

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Abstract PR010: Potentiating the efficacy of immune checkpoint blockade by targeting the epithelial-to-mesenchymal transition (EMT) in breast carcinomas von Dongre, Anushka, Rashidian, Mohammad, Ng Eaton, Elinor, Reinhardt, Ferenc, Thiru, Prat, Zagorulya, Maria, Nepal, Sunita, Banaz, Tuba, Martner, Anna, Spranger, Stefani, Weinberg, Robert A.

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Abstract B25: Inhibition of autocrine signaling as a strategy to target tumor-initiating breast cancer cells von Scheel, Christina, Dragoi, Diana, Eaton, Elinor Ng, Sophia Hsin-Jung, Li, Reinhardt, Ferenc, Weinberg, Robert A.

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Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages von Lu, Haihui, Clauser, Karl R., Tam, Wai Leong, Fröse, Julia, Ye, Xin, Eaton, Elinor Ng, Reinhardt, Ferenc, Donnenberg, Vera S., Bhargava, Rohit, Carr, Steven A., Weinberg, Robert A.

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Abstract 5082: Impact of HGF knockin microenvironment on epithelial-mesenchymal transition and cancer stem cells in a non-small cell lung cancer xenograft model von Navas, Tony, Pfister, Thomas D., Lawrence, Scott M., Srivastava, Apurva K., Kinders, Robert J., Borgel, Suzanne, Alcoser, Sergio, Hollingshead, Melinda G., Dutko, Lindsay M., Gouker, Brad A., Butcher, Donna, Ng-Eaton, Elinor, Takebe, Naoko, Lee, Young H., Bottaro, Donald P., Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.

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