Baseline patient factors impact on the clinical efficacy of benralizumab for severe asthma von Bleecker, Eugene R, Wechsler, Michael E, FitzGerald, J Mark, Menzies-Gow, Andrew, Wu, Yanping, Hirsch, Ian, Goldman, Mitchell, Newbold, Paul, Zangrilli, James G

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Benralizumab for the Prevention of COPD Exacerbations von Criner, Gerard J, Celli, Bartolome R, Brightling, Christopher E, Agusti, Alvar, Papi, Alberto, Singh, Dave, Sin, Don D, Vogelmeier, Claus F, Sciurba, Frank C, Bafadhel, Mona, Backer, Vibeke, Kato, Motokazu, Ramírez-Venegas, Alejandra, Wei, Yu-Feng, Bjermer, Leif, Shih, Vivian H, Jison, Maria, O’Quinn, Sean, Makulova, Natalya, Newbold, Paul, Goldman, Mitchell, Martin, Ubaldo J

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Biological clustering supports both “Dutch” and “British” hypotheses of asthma and chronic obstructive pulmonary disease von Ghebre, Michael A., MSc, Bafadhel, Mona, PhD, Desai, Dhananjay, MBBS, Cohen, Suzanne E., PhD, Newbold, Paul, PhD, Rapley, Laura, PhD, Woods, Jo, PhD, Rugman, Paul, PhD, Pavord, Ian D., MD, Newby, Chris, PhD, Burton, Paul R., MD, May, Richard D., PhD, Brightling, Chris E., PhD

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Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, Patients With Moderate to Severe Crohn's Disease: a Phase 2a Study von Sands, Bruce E., MD, Chen, Jingjing, PhD, Feagan, Brian G., MD, Penney, Mark, PhD, Rees, William A., Ph.D, Danese, Silvio, MD, PhD, Higgins, Peter D.R., MD, PhD, Newbold, Paul, PhD, Faggioni, Raffaella, PhD, Patra, Kaushik, PhD, Li, Jing, PhD, Klekotka, Paul, MD, PhD, Morehouse, Chris, MS, Pulkstenis, Erik, PhD, Drappa, Jörn, MD, PhD, van der Merwe, René, MBChB, Gasser, Robert A., MD

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Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases von Sridhar, Sriram, Liu, Hao, Pham, Tuyet-Hang, Damera, Gautam, Newbold, Paul

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Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma von Sehmi, Roma, Lim, Hui Fang, Mukherjee, Manali, Huang, Chynna, Radford, Katherine, Newbold, Paul, Boulet, Louis-Philippe, Dorscheid, Delbert, Martin, James G., Nair, Parameswaran

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Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity von Dagher, Rania, Kumar, Varsha, Copenhaver, Alan M, Gallagher, Sandra, Ghaedi, Mahboobe, Boyd, Jonathan, Newbold, Paul, Humbles, Alison A, Kolbeck, Roland

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Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue von Jogdand, Prajakta, Siddhuraj, Premkumar, Mori, Michiko, Sanden, Caroline, Jönsson, Jimmie, Walls, Andrew F, Kearley, Jennifer, Humbles, Alison A, Kolbeck, Roland, Bjermer, Leif, Newbold, Paul, Erjefält, Jonas S

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Eosinophil-derived neurotoxin: A biologically and analytically attractive asthma biomarker von Rutten, Bert, Young, Simon, Rhedin, Magdalena, Olsson, Marita, Kurian, Nisha, Syed, Farhat, Beech, Augusta, Fidock, Mark, Newbold, Paul, Singh, Dave, Platt, Adam, Hughes, Glen

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A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease von Calverley, Peter M A, Sethi, Sanjay, Dawson, Michelle, Ward, Christine K, Finch, Donna K, Penney, Mark, Newbold, Paul, van der Merwe, René

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Benralizumab for PDGFRA -Negative Hypereosinophilic Syndrome von Kuang, Fei Li, Legrand, Fanny, Makiya, Michelle, Ware, JeanAnne, Wetzler, Lauren, Brown, Thomas, Magee, Tamika, Piligian, Brent, Yoon, Pryscilla, Ellis, Jamie H., Sun, Xiaoping, Panch, Sandhya R., Powers, Astin, Alao, Hawwa, Kumar, Sheila, Quezado, Martha, Yan, Li, Lee, Nancy, Kolbeck, Roland, Newbold, Paul, Goldman, Mitchell, Fay, Michael P., Khoury, Paneez, Maric, Irina, Klion, Amy D.

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Profiling of Sputum Inflammatory Mediators in Asthma and Chronic Obstructive Pulmonary Disease von Bafadhel, M., McCormick, M., Saha, S., McKenna, S., Shelley, M., Hargadon, B., Mistry, V., Reid, C., Parker, D., Dodson, P., Jenkins, M., Lloyd, A., Rugman, P., Newbold, Paul, Brightling, C.E.

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Benralizumab efficacy by atopy status and serum immunoglobulin E for patients with severe, uncontrolled asthma von Chipps, Bradley E., Newbold, Paul, Hirsch, Ian, Trudo, Frank, Goldman, Mitchell

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Reductions in eosinophil biomarkers by benralizumab in patients with asthma von Pham, Tuyet-Hang, Damera, Gautam, Newbold, Paul, Ranade, Koustubh

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Pulmonary inflammation in patients with chronic obstructive pulmonary disease with higher blood eosinophil counts von Kolsum, Umme, Damera, Gautam, Pham, Tuyet-Hang, Southworth, Thomas, Mason, Sarah, Karur, Pradeep, Newbold, Paul, Singh, Dave

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You're the Flight Surgeon

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Ability of Serum IgE Concentration to Predict Exacerbation Risk and Benralizumab Efficacy for Patients with Severe Eosinophilic Asthma von Jackson, David J., Humbert, Marc, Hirsch, Ian, Newbold, Paul, Garcia Gil, Esther

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Monoclonal antibody therapy for the treatment of asthma and chronic obstructive pulmonary disease with eosinophilic inflammation von Nixon, John, Newbold, Paul, Mustelin, Tomas, Anderson, Gary P, Kolbeck, Roland

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Predictors of enhanced response with benralizumab for patients with severe asthma: pooled analysis of the SIROCCO and CALIMA studies von FitzGerald, J Mark, Bleecker, Eugene R, Menzies-Gow, Andrew, Zangrilli, James G, Hirsch, Ian, Metcalfe, Paul, Newbold, Paul, Goldman, Mitchell

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Detection of COPD Exacerbations and Compliance With Patient-Reported Daily Symptom Diaries Using a Smartphone-Based Information System von Johnston, Neil W., MSc, Lambert, Kim, RN, MSc, Hussack, Patricia, RN, de Verdier, Maria Gerhardsson, MD, PhD, Higenbottam, Tim, MD, DSc, Lewis, Jonathan, BSc, Newbold, Paul, PhD, Jenkins, Martin, MMath, Norman, Geoffrey R., PhD, Coyle, Peter V., MD, McIvor, R. Andrew, MD

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