Accurate and efficient detection of gene fusions from RNA sequencing data von Uhrig, Sebastian, Ellermann, Julia, Walther, Tatjana, Burkhardt, Pauline, Fröhlich, Martina, Hutter, Barbara, Toprak, Umut H, Neumann, Olaf, Stenzinger, Albrecht, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt

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Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis von Buchhalter, Ivo, Rempel, Eugen, Endris, Volker, Allgäuer, Michael, Neumann, Olaf, Volckmar, Anna‐Lena, Kirchner, Martina, Leichsenring, Jonas, Lier, Amelie, Winterfeld, Moritz, Penzel, Roland, Christopoulos, Petros, Thomas, Michael, Fröhling, Stefan, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

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Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels von Endris, Volker, Buchhalter, Ivo, Allgäuer, Michael, Rempel, Eugen, Lier, Amelie, Volckmar, Anna‐Lena, Kirchner, Martina, Winterfeld, Moritz, Leichsenring, Jonas, Neumann, Olaf, Penzel, Roland, Weichert, Wilko, Glimm, Hanno, Fröhling, Stefan, Winter, Hauke, Herth, Felix, Thomas, Michael, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

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Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases von Volckmar, Anna‐Lena, Leichsenring, Jonas, Kirchner, Martina, Christopoulos, Petros, Neumann, Olaf, Budczies, Jan, Morais de Oliveira, Cristiano Manuel, Rempel, Eugen, Buchhalter, Ivo, Brandt, Regine, Allgäuer, Michael, Talla, Suranand Babu, von Winterfeld, Moritz, Herpel, Esther, Goeppert, Benjamin, Lier, Amelie, Winter, Hauke, Brummer, Tilman, Fröhling, Stefan, Faehling, Martin, Fischer, Jürgen R., Heußel, Claus Peter, Herth, Felix, Lasitschka, Felix, Schirmacher, Peter, Thomas, Michael, Endris, Volker, Penzel, Roland, Stenzinger, Albrecht

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Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians von Allgäuer, Michael, Budczies, Jan, Christopoulos, Petros, Endris, Volker, Lier, Amelie, Rempel, Eugen, Volckmar, Anna-Lena, Kirchner, Martina, von Winterfeld, Moritz, Leichsenring, Jonas, Neumann, Olaf, Fröhling, Stefan, Penzel, Roland, Thomas, Michael, Schirmacher, Peter, Stenzinger, Albrecht

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Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors von Neumann, Olaf, Kesselmeier, Miriam, Geffers, Robert, Pellegrino, Rossella, Radlwimmer, Bernhard, Hoffmann, Katrin, Ehemann, Volker, Schemmer, Peter, Schirmacher, Peter, Lorenzo Bermejo, Justo, Longerich, Thomas

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Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts von Kazdal, Daniel, Endris, Volker, Allgäuer, Michael, Kriegsmann, Mark, Leichsenring, Jonas, Volckmar, Anna-Lena, Harms, Alexander, Kirchner, Martina, Kriegsmann, Katharina, Neumann, Olaf, Brandt, Regine, Talla, Suranand B., Rempel, Eugen, Ploeger, Carolin, von Winterfeld, Moritz, Christopoulos, Petros, Merino, Diana M., Stewart, Mark, Allen, Jeff, Bischoff, Helge, Meister, Michael, Muley, Thomas, Herth, Felix, Penzel, Roland, Warth, Arne, Winter, Hauke, Fröhling, Stefan, Peters, Solange, Swanton, Charles, Thomas, Michael, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

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Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis von Goeppert, Benjamin, Stichel, Damian, Toth, Reka, Fritzsche, Sarah, Loeffler, Moritz Anton, Schlitter, Anna Melissa, Neumann, Olaf, Assenov, Yassen, Vogel, Monika Nadja, Mehrabi, Arianeb, Hoffmann, Katrin, Köhler, Bruno, Springfeld, Christoph, Weichenhan, Dieter, Plass, Christoph, Esposito, Irene, Schirmacher, Peter, von Deimling, Andreas, Roessler, Stephanie

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Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains von Weinberg, Florian, Griffin, Ricarda, Fröhlich, Martina, Heining, Christoph, Braun, Sandra, Spohr, Corinna, Iconomou, Mary, Hollek, Viola, Röring, Michael, Horak, Peter, Kreutzfeldt, Simon, Warsow, Gregor, Hutter, Barbara, Uhrig, Sebastian, Neumann, Olaf, Reuss, David, Heiland, Dieter Henrik, von Kalle, Christof, Weichert, Wilko, Stenzinger, Albrecht, Brors, Benedikt, Glimm, Hanno, Fröhling, Stefan, Brummer, Tilman

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Primary pulmonary myxoid sarcoma with an unusual gene fusion between exon 7 of EWSR1 and exon 5 of CREB1 von Koelsche, Christian, Tavernar, Luca, Neumann, Olaf, Heußel, Claus Peter, Eberhardt, Ralf, Winter, Hauke, Stenzinger, Albrecht, Mechtersheimer, Gunhild

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KRAS/GNAS‐testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound‐guided workup of suspected mucinous neoplasms of the pancreas von Schmitz, Daniel, Kazdal, Daniel, Allgäuer, Michael, Trunk, Marcus, Vornhusen, Sylke, Nahm, Anna‐Maria, Doll, Matthias, Weingärtner, Simon, Endris, Volker, Penzel, Roland, Kirchner, Martina, Brandt, Regine, Neumann, Olaf, Sültmann, Holger, Budczies, Jan, Kienle, Peter, Magdeburg, Richard, Hetjens, Svetlana, Schirmacher, Peter, Bergmann, Frank, Rudi, Jochen, Stenzinger, Albrecht, Volckmar, Anna‐Lena

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Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD) von Menzel, Michael, Endris, Volker, Schwab, Constantin, Kluck, Klaus, Neumann, Olaf, Beck, Susanne, Ball, Markus, Schaaf, Christian, Fröhling, Stefan, Lichtner, Peter, Schirmacher, Peter, Kazdal, Daniel, Stenzinger, Albrecht, Budczies, Jan

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RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples von Kirchner, Martina, Neumann, Olaf, Volckmar, Anna-Lena, Stögbauer, Fabian, Allgäuer, Michael, Kazdal, Daniel, Budczies, Jan, Rempel, Eugen, Brandt, Regine, Talla, Suranand Babu, von Winterfeld, Moritz, Leichsenring, Jonas, Bochtler, Tilmann, Krämer, Alwin, Springfeld, Christoph, Schirmacher, Peter, Penzel, Roland, Endris, Volker, Stenzinger, Albrecht

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Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes von Singer, Stephan, Zhao, Ruiying, Barsotti, Anthony M., Ouwehand, Anette, Fazollahi, Mina, Coutavas, Elias, Breuhahn, Kai, Neumann, Olaf, Longerich, Thomas, Pusterla, Tobias, Powers, Maureen A., Giles, Keith M., Leedman, Peter J., Hess, Jochen, Grunwald, David, Bussemaker, Harmen J., Singer, Robert H., Schirmacher, Peter, Prives, Carol

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NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology von Mock, Andreas, Teleanu, Maria-Veronica, Kreutzfeldt, Simon, Heilig, Christoph E., Hüllein, Jennifer, Möhrmann, Lino, Jahn, Arne, Hanf, Dorothea, Kerle, Irina A., Singh, Hans Martin, Hutter, Barbara, Uhrig, Sebastian, Fröhlich, Martina, Neumann, Olaf, Hartig, Andreas, Brückmann, Sascha, Hirsch, Steffen, Grund, Kerstin, Dikow, Nicola, Lipka, Daniel B., Renner, Marcus, Bhatti, Irfan Ahmed, Apostolidis, Leonidas, Schlenk, Richard F., Schaaf, Christian P., Stenzinger, Albrecht, Schröck, Evelin, Hübschmann, Daniel, Heining, Christoph, Horak, Peter, Glimm, Hanno, Fröhling, Stefan

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First proficiency testing for NGS‐based and combined NGS‐ and FISH‐based detection of FGFR2 fusions in intrahepatic cholangiocarcinoma von Neumann, Olaf, Lehmann, Ulrich, Bartels, Stephan, Pfarr, Nicole, Albrecht, Thomas, Ilm, Katharina, Christmann, Jens, Volckmar, Anna‐Lena, Goldschmid, Hannah, Kirchner, Martina, Allgäuer, Michael, Walker, Maria, Kreipe, Hans, Tannapfel, Andrea, Weichert, Wilko, Schirmacher, Peter, Kazdal, Daniel, Stenzinger, Albrecht

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The Effect of Turning Vanes on Pressure Loss and Heat Transfer of a Ribbed Rectangular Two-Pass Internal Cooling Channel von Schüler, Marco, Zehnder, Frank, Weigand, Bernhard, von Wolfersdorf, Jens, Neumann, Sven Olaf

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Interplay of demographic variables, birth experience, and initial reactions in the prediction of symptoms of posttraumatic stress one year after giving birth von König, Julia, Schmid, Sabine, Löser, Eva, Neumann, Olaf, Buchholz, Stefan, Kästner, Ralph

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Simulation of flow in an exact replica of a diseased human carotid artery von Younis, B.A., Spring, S., Olaf Neumann, S., Weigand, B.

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Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers von Horak, Peter, Heining, Christoph, Kreutzfeldt, Simon, Hutter, Barbara, Mock, Andreas, Hüllein, Jennifer, Fröhlich, Martina, Uhrig, Sebastian, Jahn, Arne, Rump, Andreas, Gieldon, Laura, Möhrmann, Lino, Hanf, Dorothea, Teleanu, Veronica, Heilig, Christoph E, Lipka, Daniel B, Allgäuer, Michael, Ruhnke, Leo, Laßmann, Andreas, Endris, Volker, Neumann, Olaf, Penzel, Roland, Beck, Katja, Richter, Daniela, Winter, Ulrike, Wolf, Stephan, Pfütze, Katrin, Geörg, Christina, Meißburger, Bettina, Buchhalter, Ivo, Augustin, Marinela, Aulitzky, Walter E, Hohenberger, Peter, Kroiss, Matthias, Schirmacher, Peter, Schlenk, Richard F, Keilholz, Ulrich, Klauschen, Frederick, Folprecht, Gunnar, Bauer, Sebastian, Siveke, Jens Thomas, Brandts, Christian H, Kindler, Thomas, Boerries, Melanie, Illert, Anna L, von Bubnoff, Nikolas, Jost, Philipp J, Spiekermann, Karsten, Bitzer, Michael, Schulze-Osthoff, Klaus, von Kalle, Christof, Klink, Barbara, Brors, Benedikt, Stenzinger, Albrecht, Schröck, Evelin, Hübschmann, Daniel, Weichert, Wilko, Glimm, Hanno, Fröhling, Stefan

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