Solution Structure of the Antiapoptotic Protein bcl-2 von Petros, Andrew M., Medek, Ales, Nettesheim, David G., Kim, Daniel H., Yoon, Ho Sup, Swift, Kerry, Matayoshi, Edmund D., Oltersdorf, Tilman, Fesik, Stephen W.

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Discovery of a novel small molecule binding site of human survivin von Wendt, Michael D., Sun, Chaohong, Kunzer, Aaron, Sauer, Daryl, Sarris, Kathy, Hoff, Ethan, Yu, Liping, Nettesheim, David G., Chen, Jun, Jin, Sha, Comess, Kenneth M., Fan, Yihong, Anderson, Steven N., Isaac, Binumol, Olejniczak, Edward T., Hajduk, Philip J., Rosenberg, Saul H., Elmore, Steven W.

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours von Fesik, Stephen W, Rosenberg, Saul H, Oltersdorf, Tilman, Elmore, Steven W, Shoemaker, Alexander R, Armstrong, Robert C, Augeri, David J, Belli, Barbara A, Bruncko, Milan, Deckwerth, Thomas L, Dinges, Jurgen, Hajduk, Philip J, Joseph, Mary K, Kitada, Shinichi, Korsmeyer, Stanley J, Kunzer, Aaron R, Letai, Anthony, Li, Chi, Mitten, Michael J, Nettesheim, David G, Ng, ShiChung, Nimmer, Paul M, O'Connor, Jacqueline M, Oleksijew, Anatol, Petros, Andrew M, Reed, John C, Shen, Wang, Tahir, Stephen K, Thompson, Craig B, Tomaselli, Kevin J, Wang, Baole, Wendt, Michael D, Zhang, Haichao

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Discovery of a Potent Inhibitor of the Antiapoptotic Protein Bcl-xL from NMR and Parallel Synthesis von Petros, Andrew M, Dinges, Jurgen, Augeri, David J, Baumeister, Steven A, Betebenner, David A, Bures, Mark G, Elmore, Steven W, Hajduk, Philip J, Joseph, Mary K, Landis, Shelley K, Nettesheim, David G, Rosenberg, Saul H, Shen, Wang, Thomas, Sheela, Wang, Xilu, Zanze, Irini, Zhang, Haichao, Fesik, Stephen W

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Solution Structure of the Amino-Terminal Fragment of Urokinase-Type Plasminogen Activator von Hansen, Andrew P, Petros, Andrew M, Meadows, Robert P, Nettesheim, David G, Mazar, Andrew P, Olejniczak, Edward T, Xu, Robert X, Pederson, Terry M, Henkin, Jack, Fesik, Stephen W

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NMR-Based Modification of Matrix Metalloproteinase Inhibitors with Improved Bioavailability von Hajduk, Philip J, Shuker, Suzanne B, Nettesheim, David G, Craig, Richard, Augeri, David J, Betebenner, David, Albert, Daniel H, Guo, Yan, Meadows, Robert P, Xu, Lianhong, Michaelides, Michael, Davidsen, Steven K, Fesik, Stephen W

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The Secondary Structure of the Ets Domain of Human Fli-1 Resembles that of the Helix-Turn-Helix DNA-Binding Motif of the Escherichia coli Catabolite Gene Activator Protein von Liang, H, Olejniczak, E T, Mao, X, Nettesheim, D G, Yu, L, Thompson, C B, Fesik, S W

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Tertiary structure of human complement component C5a in solution from nuclear magnetic resonance data von Zuiderweg, Erik R. P, Nettesheim, David G, Mollison, Karl W, Carter, George W

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Discovery of a Potent Inhibitor of the Antiapoptotic Protein Bcl-x L from NMR and Parallel Synthesis von Petros, Andrew M., Dinges, Jurgen, Augeri, David J., Baumeister, Steven A., Betebenner, David A., Bures, Mark G., Elmore, Steven W., Hajduk, Philip J., Joseph, Mary K., Landis, Shelley K., Nettesheim, David G., Rosenberg, Saul H., Shen, Wang, Thomas, Sheela, Wang, Xilu, Zanze, Irini, Zhang, Haichao, Fesik, Stephen W.

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Solution structure of the ets domain of Fli-1 when bound to DNA von Liang, Heng, Mao, Xiaohong, Olejniczak, Edward T, Nettesheim, David G, Yu, Liping, Meadows, Robert P, Thompson, Craig B, Fesik, Stephen W

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Improved NMR Structures of Protein/Ligand Complexes Using Residual Dipolar Couplings von Olejniczak, Edward T, Meadows, Robert P, Wang, Hong, Cai, Mengli, Nettesheim, David G, Fesik, Stephen W

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Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies von PETROS, ANDREW M., NETTESHEIM, DAVID G., WANG, YI, OLEJNICZAK, EDWARD T., MEADOWS, ROBERT P., MACK, JAMEY, SWIFT, KERRY, MATAYOSHI, EDMUND D., ZHANG, HAICHAO, THOMPSON, CRAIG B., FESIK, STEPHEN W.

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Solution Structure of a Low Molecular Weight Protein Tyrosine Phosphatase von Logan, Timothy M, Zhou, Ming-Ming, Nettesheim, David G, Meadows, Robert P, Van Etten, Robert L, Fesik, Stephen W

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Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR von Meadows, Robert P, Nettesheim, David G, Xu, Robert X, Olejniczak, Edward T, Petros, Andrew M, Holzman, Thomas F, Severin, Jean, Gubbins, Earl, Smith, Harriet, Fesik, Stephen W

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Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12 von Wiedeman, Paul E, Fesik, Stephen W, Petros, Andrew M, Nettesheim, David G, Mollison, Karl W, Lane, Benjamin C, Or, Yat Sun, Luly, Jay R

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Sequential resonance assignments of oxidized high-potential iron-sulfur protein from Chromatium vinosum von Nettesheim, David G, Harder, Scott R, Feinberg, Benjamin A, Otvos, James D

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Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies von PETROS, ANDREW M., NETTESHEIM, DAVID G., WANG, YI, OLEJNICZAK, EDWARD T., MEADOWS, ROBERT P., MACK, JAMEY, SWIFT, KERRY, MATAYOSHI, EDMUND D., ZHANG, HAICHAO, THOMPSON, CRAIG B., FESIK, STEPHEN W.

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Products of metal exchange reactions of metallothionein von Nettesheim, David G, Engeseth, Helen R, Otvos, James D

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Proton nuclear magnetic resonance studies on the variant-3 neurotoxin from Centruroides sculpturatus Ewing: sequential assignment of resonances von Nettesheim, David G, Klevit, Rachel E, Drobny, Gary, Watt, Dean D, Krishna, N. Rama

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Proton nuclear magnetic resonance characterization of the aromatic residues in the variant-3 neurotoxin from Centruroides sculpturatus Ewing von Krishna, N. Rama, Nettesheim, David G, Klevit, Rachel E, Drobny, Gary, Watt, Dean D, Bugg, Charles E

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