Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics von Riether, Doris, Harcken, Christian, Razavi, Hossein, Kuzmich, Daniel, Gilmore, Thomas, Bentzien, Jörg, Pack, Edward J, Souza, Donald, Nelson, Richard M, Kukulka, Alison, Fadra, Tazmeen N, Zuvela-Jelaska, Ljiljana, Pelletier, Josephine, Dinallo, Roger, Panzenbeck, Mark, Torcellini, Carol, Nabozny, Gerald H, Thomson, David S

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Trifluoromethyl group as a pharmacophore : Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand von BETAGERI, Raj, YAN ZHANG, PAW, Zofia, SHIH, Daw-Tsun, SHIH, Cheng-Kon, ZUVELA-JELASKA, Ljiljana, NABOZNY, Gerald, THOMSON, David S, ZINDELL, Renee M, KUZMICH, Daniel, KIRRANE, Thomas M, BENTZIEN, Jörg, CARDOZO, Mario, CAPOLINO, Alison J, FADRA, Tazmeen N, NELSON, Richard M

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Three Mechanistically Distinct Kinase Assays Compared: Measurement of Intrinsic ATPase Activity Identified the Most Comprehensive Set of ITK Inhibitors von Kashem, Mohammed A., Nelson, Richard M., Yingling, Jeffrey D., Pullen, Steven S., Prokopowicz, III, Anthony S., Jones, Jessi Wildeson, Wolak, John P., Rogers, George R., Morelock, Maurice M., Snow, Roger J., Homon, Carol Ann, Jakes, Scott

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Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores von Betageri, Raj, Gilmore, Thomas, Kuzmich, Daniel, Kirrane, Thomas M., Bentzien, Jörg, Wiedenmayer, Dieter, Bekkali, Younes, Regan, John, Berry, Angela, Latli, Bachir, Kukulka, Alison J., Fadra, Tazmeen N., Nelson, Richard M., Goldrick, Susan, Zuvela-Jelaska, Ljiljana, Souza, Don, Pelletier, Josephine, Dinallo, Roger, Panzenbeck, Mark, Torcellini, Carol, Lee, Heewon, Pack, Edward, Harcken, Christian, Nabozny, Gerald, Thomson, David S.

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ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULES IN HUMAN DISEASE von Bevilacqua, M.D., Ph.D, Michael P, Nelson, Ph.D, Richard M, Mannori, M.D., Ph.D, Gianna, Cecconi, M.D, Oliviero

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Discovery and SAR study of novel dihydroquinoline-containing glucocorticoid receptor agonists von Takahashi, Hidenori, Bekkali, Younes, Capolino, Alison J., Gilmore, Thomas, Goldrick, Susan E., Kaplita, Paul V., Liu, Lisa, Nelson, Richard M., Terenzio, Donna, Wang, Ji, Zuvela-Jelaska, Ljiljana, Proudfoot, John, Nabozny, Gerald, Thomson, David

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Identification of Highly Efficacious Glucocorticoid Receptor Agonists with a Potential for Reduced Clinical Bone Side Effects von Harcken, Christian, Riether, Doris, Kuzmich, Daniel, Liu, Pingrong, Betageri, Raj, Ralph, Mark, Emmanuel, Michel, Reeves, Jonathan T, Berry, Angela, Souza, Donald, Nelson, Richard M, Kukulka, Alison, Fadra, Tazmeen N, Zuvela-Jelaska, Ljiljana, Dinallo, Roger, Bentzien, Jörg, Nabozny, Gerald H, Thomson, David S

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Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore von Razavi, Hossein, Riether, Doris, Harcken, Christian, Bentzien, Jörg, Dinallo, Roger M, Souza, Donald, Nelson, Richard M, Kukulka, Alison, Fadra-Khan, Tazmeen N, Pack, Jr, Edward J, Zuvela-Jelaska, Ljiljana, Pelletier, Josephine, Panzenbeck, Mark, Torcellini, Carol A, Proudfoot, John R, Nabozny, Gerald H, Thomson, David S

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Optimization of Drug-Like Properties of Nonsteroidal Glucocorticoid Mimetics and Identification of a Clinical Candidate von Harcken, Christian, Riether, Doris, Liu, Pingrong, Razavi, Hossein, Patel, Usha, Lee, Thomas, Bosanac, Todd, Ward, Yancey, Ralph, Mark, Chen, Zhidong, Souza, Donald, Nelson, Richard M, Kukulka, Alison, Fadra-Khan, Tazmeen N, Zuvela-Jelaska, Ljiljana, Patel, Mita, Thomson, David S, Nabozny, Gerald H

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A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay von Kashem, Mohammed A, Kennedy, Charles A, Fogarty, Kylie E, Dimock, Janice R, Zhang, Yunlong, Sanville-Ross, Mary L, Skow, Donna J, Brunette, Steven R, Swantek, Jennifer L, Hummel, Heidi S, Swindle, John, Nelson, Richard M

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A high-throughput scintillation proximity assay for sphingosine-1-phosphate lyase von Kashem, Mohammed A, Wa, Chunling, Wolak, John P, Grafos, Nicholas S, Ryan, Kelli R, Sanville-Ross, Mary L, Fogarty, Kylie E, Rybina, Irina V, Shoultz, Alycia, Molinaro, Teresa, Desai, Sudha N, Rajan, Anusha, Huber, John D, Nelson, Richard M

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Quinol-4-ones as Steroid A-Ring Mimetics in Nonsteroidal Dissociated Glucocorticoid Agonists von Regan, John, Lee, Thomas W, Zindell, Renée M, Bekkali, Younes, Bentzien, Jörg, Gilmore, Thomas, Hammach, Abdelhakim, Kirrane, Thomas M, Kukulka, Alison J, Kuzmich, Daniel, Nelson, Richard M, Proudfoot, John R, Ralph, Mark, Pelletier, Josephine, Souza, Donald, Zuvela-Jelaska, Lijiljana, Nabozny, Gerald, Thomson, David S

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Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands von Takahashi, Hidenori, Bekkali, Younes, Capolino, Alison J., Gilmore, Thomas, Goldrick, Susan E., Nelson, Richard M., Terenzio, Donna, Wang, Ji, Zuvela-Jelaska, Ljiljana, Proudfoot, John, Nabozny, Gerald, Thomson, David

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New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site von Moss, Neil, Breitfelder, Steffen, Betageri, Raj, Cirillo, Pier F., Fadra, Tazmeen, Hickey, Eugene R., Kirrane, Thomas, Kroe, Rachel R., Madwed, Jeffrey, Nelson, Richard M., Pargellis, Christopher A., Qian, Kevin C., Regan, John, Swinamer, Alan, Torcellini, Carol

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Interaction of Secretory Leukocyte Protease Inhibitor with Heparin Inhibits Proteases Involved in Asthma von Fath, Melissa A., Wu, Xiaojun, Hileman, Ronald E., Linhardt, Robert J., Kashem, Mohammed A., Nelson, Richard M., Wright, Clifford D., Abraham, William M.

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A general method of site-specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction von Nelson, Richard M., Long, George L.

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Heparin Promotes the Inactivation of Antithrombin by Neutrophil Elastase von Jordan, Robert E., Kilpatrick, Jaleh, Nelson, Richard M.

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Carbohydrate-Protein Interactions in Vascular Biology von Nelson, R M, Venot, A, Bevilacqua, M P, Linhardt, R J, Stamenkovic, I

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Selectins von BEVILACQUA, M. P, NELSON, R. M

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Heparin Oligosaccharides Bind L- and P-Selectin and Inhibit Acute Inflammation von Nelson, Richard M., Cecconi, Oliviero, Roberts, W. Gregory, Aruffo, Alejandro, Linhardt, Robert J., Bevilacqua, Michael P.

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