The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors von Nelson, Erik A., Walker, Sarah R., Weisberg, Ellen, Bar-Natan, Michal, Barrett, Rosemary, Gashin, Laurie B., Terrell, Shariya, Klitgaard, Josephine L., Santo, Loredana, Addorio, Martha R., Ebert, Benjamin L., Griffin, James D., Frank, David A.

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Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways von Takakura, Ayumi, Nelson, Erik A., Haque, Nadeem, Humphreys, Benjamin D., Zandi-Nejad, Kambiz, Frank, David A., Zhou, Jing

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STAT5 Outcompetes STAT3 To Regulate the Expression of the Oncogenic Transcriptional Modulator BCL6 von Walker, Sarah R., Nelson, Erik A., Yeh, Jennifer E., Pinello, Luca, Yuan, Guo-Cheng, Frank, David A.

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Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3 von Nelson, Erik A., Walker, Sarah R., Kepich, Alicia, Gashin, Laurie B., Hideshima, Teru, Ikeda, Hiroshi, Chauhan, Dharminder, Anderson, Kenneth C., Frank, David A.

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CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3 von Egusquiaguirre, Susana P., Liu, Suhu, Tošić, Isidora, Jiang, Kevin, Walker, Sarah R., Nicolais, Maria, Saw, Tzuen Yih, Xiang, Michael, Bartel, Katarina, Nelson, Erik A., Frank, David A.

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Reciprocal Effects of STAT5 and STAT3 in Breast Cancer von Walker, Sarah R, Nelson, Erik A, Zou, Lihua, Chaudhury, Mousumi, Signoretti, Sabina, Richardson, Andrea, Frank, David A

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Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling von Walker, Sarah R, Chaudhury, Mousumi, Nelson, Erik A, Frank, David A

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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma von Catenacci, Daniel V.T., Cervantes, Gustavo, Yala, Soheil, Nelson, Erik A., El-Hashani, Essam, Kanteti, Rajani, El Dinali, Mohamed, Hasina, Rifat, Brägelmann, Johannes, Seiwert, Tanguy, Sanicola, Michele, Henderson, Les, Grushko, Tatyana A., Olopade, Olufunmilayo, Karrison, Theodore, Bang, Yung-Jue, Kim, Woo Ho, Tretiakova, Maria, Vokes, Everett, Frank, David A., Kindler, Hedy L., Huet, Heather, Salgia, Ravi

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IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo von Zorn, Emmanuel, Nelson, Erik A., Mohseni, Mehrdad, Porcheray, Fabrice, Kim, Haesook, Litsa, Despina, Bellucci, Roberto, Raderschall, Elke, Canning, Christine, Soiffer, Robert J., Frank, David A., Ritz, Jerome

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Isolation of Unique STAT5 Targets by Chromatin Immunoprecipitation-based Gene Identification von Nelson, Erik A., Walker, Sarah R., Alvarez, James V., Frank, David A.

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A chemical biology approach to developing STAT inhibitors: molecular strategies for accelerating clinical translation von Nelson, Erik A, Sharma, Sreenath V, Settleman, Jeffrey, Frank, David A

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Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses von Brown, Jennifer R., Walker, Sarah R., Heppler, Lisa N., Tyekucheva, Svitlana, Nelson, Erik A., Klitgaard, Josephine, Nicolais, Maria, Kroll, Yasmin, Xiang, Michael, Yeh, Jennifer E., Chaudhury, Mousumi, Giaccone, Zachary T., Fernandes, Stacey M., Jacobsen, Eric D., Fisher, David C., Freedman, Arnold S., Davids, Matthew S., Supko, Jeffrey G., Wu, Catherine, Frank, David A.

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Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2 von Liu, Suhu, Walker, Sarah R, Nelson, Erik A, Cerulli, Robert, Xiang, Michael, Toniolo, Patricia A, Qi, Jun, Stone, Richard M, Wadleigh, Martha, Bradner, James E, Frank, David A

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Identification of Human STAT5-dependent Gene Regulatory Elements Based on Interspecies Homology von Nelson, Erik A., Walker, Sarah R., Li, Wei, Liu, X. Shirley, Frank, David A.

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Antimyeloma Activity of a Multitargeted Kinase Inhibitor, AT9283, via Potent Aurora Kinase and STAT3 Inhibition Either Alone or in Combination with Lenalidomide von SANTO, Loredana, HIDESHIMA, Teru, UNITT, Christine, SQUIRES, Matt, YIGUO HU, CHAUHAN, Dharminder, MAHINDRA, Anuj, MUNSHI, Nikhil C, ANDERSON, Kenneth C, RAJE, Noopur, CIRSTEA, Diana, BANDI, Madhavi, NELSON, Erik A, GORGUN, Gullu, RODIG, Scott, VALLET, Sonia, POZZI, Samantha, PATEL, Kishan

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STAT signaling in the pathogenesis and treatment of myeloid malignancies von Bar-Natan, Michal, Nelson, Erik A., Xiang, Michael, Frank, David A.

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The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations von Nelson, Erik A, Walker, Sarah R, Xiang, Michael, Weisberg, Ellen, Bar-Natan, Michal, Barrett, Rosemary, Liu, Suiyang, Kharbanda, Surender, Christie, Amanda L, Nicolais, Maria, Griffin, James D, Stone, Richard M, Kung, Andrew L, Frank, David A

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The amino terminal and E2F interaction domains are critical for C/EBPα-mediated induction of granulopoietic development of hematopoietic cells von D’Alo’, Francesco, Johansen, Lisa M., Nelson, Erik A., Radomska, Hanna S., Evans, Erica K., Zhang, Pu, Nerlov, Claus, Tenen, Daniel G.

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Discovery and characterization of novel mutant FLT3 kinase inhibitors von Weisberg, Ellen, Choi, Hwan Geun, Barrett, Rosemary, Zhou, Wenjun, Zhang, Jianming, Ray, Arghya, Nelson, Erik A, Jiang, Jingrui, Moreno, Daisy, Stone, Richard, Galinsky, Ilene, Fox, Edward, Adamia, Sophia, Kung, Andrew L, Gray, Nathanael S, Griffin, James D

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Survey of Diversity and Abundance of Ground-dwelling Arthropods in a Black Walnut-forage Alley-cropped System in the Mid-western United States von Stamps, W. Terrell, Nelson, Erik A., Linit, Marc J.

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