Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation von Lange, Sven M., Nelen, Marina I., Cohen, Philip, Kulathu, Yogesh

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RORγt and RORα signature genes in human Th17 cells von Castro, Glenda, Liu, Xuejun, Ngo, Karen, De Leon-Tabaldo, Aimee, Zhao, Shanrong, Luna-Roman, Rosa, Yu, Jingxue, Cao, Tinghua, Kuhn, Robert, Wilkinson, Patrick, Herman, Krystal, Nelen, Marina I, Blevitt, Jonathan, Xue, Xiaohua, Fourie, Anne, Fung-Leung, Wai-Ping

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Identification and biological evaluation of thiazole-based inverse agonists of RORγt von Gege, Christian, Cummings, Maxwell D., Albers, Michael, Kinzel, Olaf, Kleymann, Gerald, Schlüter, Thomas, Steeneck, Christoph, Nelen, Marina I., Milligan, Cindy, Spurlino, John, Xue, Xiaohua, Leonard, Kristi, Edwards, James P., Fourie, Anne, Goldberg, Steven D., Hoffmann, Thomas

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Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein–Protein Interaction von Blevitt, Jonathan M, Hack, Michael D, Herman, Krystal L, Jackson, Paul F, Krawczuk, Paul J, Lebsack, Alec D, Liu, Annie X, Mirzadegan, Taraneh, Nelen, Marina I, Patrick, Aaron N, Steinbacher, Stefan, Milla, Marcos E, Lumb, Kevin J

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Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry von Damm-Ganamet, Kelly L, Arora, Nidhi, Becart, Stephane, Edwards, James P, Lebsack, Alec D, McAllister, Heather M, Nelen, Marina I, Rao, Navin L, Westover, Lori, Wiener, John J. M, Mirzadegan, Taraneh

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Universal Screening Methods and Applications of ThermoFluor von Cummings, Maxwell D., Farnum, Michael A., Nelen, Marina I.

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3-Substituted Quinolines as RORγt Inverse Agonists von Tanis, Virginia M., Venkatesan, Hariharan, Cummings, Maxwell D., Albers, Michael, Kent Barbay, J., Herman, Krystal, Kummer, David A., Milligan, Cynthia, Nelen, Marina I., Nishimura, Rachel, Schlueter, Thomas, Scott, Brian, Spurlino, John, Wolin, Ronald, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation von Soroosh, Pejman, Wu, Jiejun, Xue, Xiaohua, Song, Jiao, Sutton, Steven W., Sablad, Marciano, Yu, Jingxue, Nelen, Marina I., Liu, Xuejun, Castro, Glenda, Luna, Rosa, Crawford, Shelby, Banie, Homayon, Dandridge, Rose A., Deng, Xiaohu, Bittner, Anton, Kuei, Chester, Tootoonchi, Mandana, Rozenkrants, Natasha, Herman, Krystal, Gao, Jingjin, Yang, Xia V., Sachen, Kacey, Ngo, Karen, Fung-Leung, Wai-Ping, Nguyen, Steven, de Leon-Tabaldo, Aimee, Blevitt, Jonathan, Zhang, Yan, Cummings, Maxwell D., Rao, Tadimeti, Mani, Neelakandha S., Liu, Changlu, McKinnon, Murray, Milla, Marcos E., Fourie, Anne M., Sun, Siquan

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Double-Level "Orthogonal" Dynamic Combinatorial Libraries on Transition Metal Template von Goral, Vasiliy, Nelen, Marina I., Eliseev, Alexey V., Lehn, Jean-Marie

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Water-Soluble, Core-Modified Porphyrins as Novel, Longer-Wavelength-Absorbing Sensitizers for Photodynamic Therapy von Stilts, Corey E, Nelen, Marina I, Hilmey, David G, Davies, Sherry R, Gollnick, Sandra O, Oseroff, Allan R, Gibson, Scott L, Hilf, Russell, Detty, Michael R

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Iodination of Organic Substrates with Halide Salts and H2O2 Using an Organotelluride Catalyst von Detty, Michael R, Higgs, Donald E, Nelen, Marina I

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Use of Molecular Recognition To Drive Chemical Evolution. 1. Controlling the Composition of an Equilibrating Mixture of Simple Arginine Receptors von Eliseev, Alexey V, Nelen, Marina I

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2,4,6-Triarylchalcogenopyrylium Dyes Related in Structure to the Antitumor Agent AA1 as in Vitro Sensitizers for the Photodynamic Therapy of Cancer von Leonard, Kristi A, Nelen, Marina I, Anderson, Linda T, Gibson, Scott L, Hilf, Russell, Detty, Michael R

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A Selenopyrylium Photosensitizer for Photodynamic Therapy Related in Structure to the Antitumor Agent AA1 with Potent in Vivo Activity and No Long-Term Skin Photosensitization von Leonard, Kristi A, Hall, Jonathan P, Nelen, Marina I, Davies, Sherry R, Gollnick, Sandra O, Camacho, Sue, Oseroff, Allan R, Gibson, Scott L, Hilf, Russell, Detty, Michael R

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Decrypting the Biochemical Function of an Essential Gene from Streptococcus pneumoniae Using ThermoFluor® Technology von Carver, Theodore E., Bordeau, Brian, Cummings, Maxwell D., Petrella, Eugene C., Pucci, Michael J., Zawadzke, Laura E., Dougherty, Brian A., Tredup, Jeffrey A., Bryson, James W., Yanchunas, Joseph, Doyle, Michael L., Witmer, Mark R., Nelen, Marina I., DesJarlais, Renee L., Jaeger, Edward P., Devine, Heather, Asel, Eric D., Springer, Barry A., Bone, Roger, Salemme, F. Raymond, Todd, Matthew J.

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Synthesis and Evaluation of Chalcogenopyrylium Dyes as Potential Sensitizers for the Photodynamic Therapy of Cancer von Leonard, Kristi A, Nelen, Marina I, Simard, Todd P, Davies, Sherry R, Gollnick, Sandra O, Oseroff, Allan R, Gibson, Scott L, Hilf, Russell, Chen, Lan Bo, Detty, Michael R

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Water-Soluble, Core-Modified Porphyrins as Novel, Longer-Wavelength-Absorbing Sensitizers for Photodynamic Therapy. II. Effects of Core Heteroatoms and Meso-Substituents on Biologi... von Hilmey, David G, Abe, Masako, Nelen, Marina I, Stilts, Corey E, Baker, Gary A, Baker, Sheila N, Bright, Frank V, Davies, Sherry R, Gollnick, Sandra O, Oseroff, Allan R, Gibson, Scott L, Hilf, Russell, Detty, Michael R

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Synthesis and Mass Spectrometry Studies of Branched Oxime Ether Libraries. Mapping the Substitution Motif via Linker Stability and Fragmentation Pattern von Nazarpack-Kandlousy, Noureddin, Nelen, Marina I, Goral, Vasiliy, Eliseev, Alexey V

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ROR[gamma]t and ROR[alpha] signature genes in human Th17 cells von Castro, Glenda, Liu, Xuejun, Ngo, Karen, De Leon-Tabaldo, Aimee, Zhao, Shanrong, Luna-Roman, Rosa, Yu, Jingxue, Cao, Tinghua, Kuhn, Robert, Wilkinson, Patrick, Herman, Krystal, Nelen, Marina I, Blevitt, Jonathan, Xue, Xiaohua, Fourie, Anne, Fung-Leung, Wai-Ping

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Affinity assays for decrypting protein targets of unknown function von Todd, Matthew J., Cummings, Maxwell D., Nelen, Marina I.

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