Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809 von Van Goor, Fredrick, Hadida, Sabine, Grootenhuis, Peter D. J, Burton, Bill, Stack, Jeffrey H, Straley, Kimberly S, Decker, Caroline J, Miller, Mark, McCartney, Jason, Olson, Eric R, Wine, Jeffrey J, Frizzell, Ray A, Ashlock, Melissa, Negulescu, Paul A

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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770 von Van Goor, Fredrick, Hadida, Sabine, Grootenhuis, Peter D.J, Burton, Bill, Cao, Dong, Neuberger, Tim, Turnbull, Amanda, Singh, Ashvani, Joubran, John, Hazlewood, Anna, Zhou, Jinglan, McCartney, Jason, Arumugam, Vijayalaksmi, Decker, Caroline, Yang, Jennifer, Young, Chris, Olson, Eric R, Wine, Jeffery J, Frizzell, Raymond A, Ashlock, Melissa, Negulescu, Paul

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Discovery of N‑(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, Ivacaftor), a Potent and Orally Bioavailable CFTR Potentiator von Hadida, Sabine, Van Goor, Fredrick, Zhou, Jinglan, Arumugam, Vijayalaksmi, McCartney, Jason, Hazlewood, Anna, Decker, Caroline, Negulescu, Paul, Grootenhuis, Peter D. J

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Pharmacology and Mechanism of Action of Suzetrigine, a Potent and Selective NaV1.8 Pain Signal Inhibitor for the Treatment of Moderate to Severe Pain von Osteen, Jeremiah D., Immani, Swapna, Tapley, Tim L., Indersmitten, Tim, Hurst, Nicole W., Healey, Tiffany, Aertgeerts, Kathleen, Negulescu, Paul A., Lechner, Sandra M.

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Characterization of voltage-gated sodium-channel blockers by electrical stimulation and fluorescence detection of membrane potential von Huang, Chien-Jung, Harootunian, Alec, Maher, Michael P, Quan, Catherine, Raj, Christopher D, McCormack, Ken, Numann, Randal, Negulescu, Paul A, González, Jesús E

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G970R‐CFTR Mutation (c.2908G>C) Results Predominantly in a Splicing Defect von Fidler, Meredith C., Buckley, Alexandra, Sullivan, James C., Statia, Marvin, Boj, Sylvia F., Vries, Robert G. J., Munck, Anne, Higgins, Mark, Moretto Zita, Matteo, Negulescu, Paul, Goor, Fredrick, De Boeck, Kris

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A genetically encoded, fluorescent indicator for cyclic AMP in living cells von Zaccolo, Manuela, De Giorgi, Francesca, Cho, Charles Y., Feng, Luxin, Knapp, Tom, Negulescu, Paul A., Taylor, Susan S., Tsien, Roger Y., Pozzan, Tullio

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Jennings Worley III von Negulescu, Paul

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Cell-based assays and instrumentation for screening ion-channel targets von González, Jesús E, Oades, Kahuku, Leychkis, Yan, Harootunian, Alec, Negulescu, Paul A

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Intracellular Calcium Dependence of Gene Expression in Single T Lymphocytes von Negulescu, Paul A., Shastri, Nilabh, Cahalan, Michael D.

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Selective Inhibition of NaV1.8 with VX-548 for Acute Pain von Jones, Jim, Correll, Darin J., Lechner, Sandra M., Jazic, Ina, Miao, Xiaopeng, Shaw, David, Simard, Christopher, Osteen, Jeremiah D., Hare, Brian, Beaton, Alina, Bertoch, Todd, Buvanendran, Asokumar, Habib, Ashraf S., Pizzi, Lois J., Pollak, Richard A., Weiner, Scott G., Bozic, Carmen, Negulescu, Paul, White, Paul F.

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Intracellular detection assays for high-throughput screening von González, Jesús E, Negulescu, Paul A

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Rescue of ΔF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules von Van Goor, Fredrick, Straley, Kimberly S., Cao, Dong, González, Jesús, Hadida, Sabine, Hazlewood, Anna, Joubran, John, Knapp, Tom, Makings, Lewis R., Miller, Mark, Neuberger, Timothy, Olson, Eric, Panchenko, Victor, Rader, James, Singh, Ashvani, Stack, Jeffrey H., Tung, Roger, Grootenhuis, Peter D. J., Negulescu, Paul

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Selective Inhibition of Na V 1.8 with VX-548 for Acute Pain von Jones, Jim, Correll, Darin J, Lechner, Sandra M, Jazic, Ina, Miao, Xiaopeng, Shaw, David, Simard, Christopher, Osteen, Jeremiah D, Hare, Brian, Beaton, Alina, Bertoch, Todd, Buvanendran, Asokumar, Habib, Ashraf S, Pizzi, Lois J, Pollak, Richard A, Weiner, Scott G, Bozic, Carmen, Negulescu, Paul, White, Paul F

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Pharmacology and Mechanism of Action of Suzetrigine, a Potent and Selective Na V 1.8 Pain Signal Inhibitor for the Treatment of Moderate to Severe Pain von Osteen, Jeremiah D, Immani, Swapna, Tapley, Tim L, Indersmitten, Tim, Hurst, Nicole W, Healey, Tiffany, Aertgeerts, Kathleen, Negulescu, Paul A, Lechner, Sandra M

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High-Throughput Screening Strategies for Cardiac Ion Channels von Numann, Randy, Negulescu, Paul A

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Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter von Zlokarnik, Gregor, Negulescu, Paul A., Knapp, Thomas E., Mere, Lora, Burres, Neal, Feng, Luxin, Whitney, Michael, Roemer, Klaus, Tsien, Roger Y.

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G970R-CFTR Mutation (c.2908G>C) Results Predominantly in a Splicing Defect von Fidler, Meredith C, Buckley, Alexandra, Sullivan, James C, Statia, Marvin, Boj, Sylvia F, Vries, Robert G.J, Munck, Anne, Higgins, Mark, Zita, Matteo Moretto, Negulescu, Paul, van Goor, Fredrick, De Boeck, Christiane

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Polarity of T Cell Shape, Motility, and Sensitivity to Antigen von Negulescu, Paul A., Krasieva, Tatiana B., Khan, Abrar, Kerschbaum, Hubert H., Cahalan, Michael D.

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Cellular biosensors for drug discovery von Durick, K, Negulescu, P

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