Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation von Purohit, Anil, Rokita, Adam G, Guan, Xiaoqun, Chen, Biyi, Koval, Olha M, Voigt, Niels, Neef, Stefan, Sowa, Thomas, Gao, Zhan, Luczak, Elizabeth D, Stefansdottir, Hrafnhildur, Behunin, Andrew C, Li, Na, El-Accaoui, Ramzi N, Yang, Baoli, Swaminathan, Paari Dominic, Weiss, Robert M, Wehrens, Xander H.T, Song, Long-Sheng, Dobrev, Dobromir, Maier, Lars S, Anderson, Mark E

Volltext

Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation von Hamdani, Nazha, Krysiak, Judith, Kreusser, Michael M, Neef, Stefan, dos Remedios, Cristobal G, Maier, Lars S, Krüger, Markus, Backs, Johannes, Linke, Wolfgang A

Volltext

Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells von MAURITZ, Christina, SCHWANKE, Kristin, HASENFUSS, Gerd, MARTIN, Ulrich, REPPEL, Michael, NEEF, Stefan, KATSIRNTAKI, Katherina, MAIER, Lars S, NGUEMO, Filomain, MENKE, Sandra, HAUSTEIN, Moritz, HESCHELER, Juergen

Volltext

δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload von Backs, Johannes, Backs, Thea, Neef, Stefan, Kreusser, Michael M, Lehmann, Lorenz H, Patrick, David M, Grueter, Chad E, Qi, Xiaoxia, Richardson, James A, Hill, Joseph A, Katus, Hugo A, Bassel-Duby, Rhonda, Maier, Lars S, Olson, Eric N

Volltext

Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure von Sag, Can M, Wadsack, Daniel P, Khabbazzadeh, Sepideh, Abesser, Marco, Grefe, Clemens, Neumann, Kay, Opiela, Marie-Kristin, Backs, Johannes, Olson, Eric N, Brown, Joan Heller, Neef, Stefan, Maier, Sebastian K G, Maier, Lars S

Volltext

Mitogen-Activated Protein Kinase-Activated Protein Kinases 2 and 3 Regulate SERCA2a Expression and Fiber Type Composition To Modulate Skeletal Muscle and Cardiomyocyte Function von Scharf, Madeleine, Neef, Stefan, Freund, Robert, Geers-Knörr, Cornelia, Franz-Wachtel, Mirita, Brandis, Almuth, Krone, Dorothee, Schneider, Heike, Groos, Stephanie, Menon, Manoj B., Chang, Kin-Chow, Kraft, Theresia, Meissner, Joachim D., Boheler, Kenneth R., Maier, Lars S., Gaestel, Matthias, Scheibe, Renate J.

Volltext

Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak von Dewenter, Matthias, Seitz, Tilmann, Steinbrecher, Julia H., Westenbrink, B. Daan, Ling, Haiyun, Lehnart, Stephan E., Wehrens, Xander H.T., Backs, Johannes, Brown, Joan Heller, Maier, Lars S., Neef, Stefan

Volltext

Ethanol-Induced Atrial Fibrillation Results From Late I Na and Can Be Prevented by Ranolazine von Mustroph, Julian, Baier, Maria J., Unsin, Denise, Provaznik, Zdenek, Kozakov, Kostiantyn, Lebek, Simon, Tarnowski, Daniel, Schildt, Sönke, Voigt, Niels, Wagner, Stefan, Maier, Lars S., Neef, Stefan

Volltext

CaMKII-Dependent Diastolic SR Ca2+ Leak and Elevated Diastolic Ca2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation von Neef, Stefan, Dybkova, Nataliya, Sossalla, Samuel, Ort, Katharina R, Fluschnik, Nina, Neumann, Kay, Seipelt, Ralf, Schöndube, Friedrich A, Hasenfuss, Gerd, Maier, Lars S

Volltext

Reduction of SR Ca2+ leak and arrhythmogenic cellular correlates by SMP-114, a novel CaMKII inhibitor with oral bioavailability von Neef, Stefan, Mann, Christian, Zwenger, Anne, Dybkova, Nataliya, Maier, Lars S.

Volltext

Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation von Purohit, Anil, Rokita, Adam G, Guan, Xiaoqun, Chen, Biyi, Koval, Olha M, Voigt, Niels, Neef, Stefan, Sowa, Thomas, Gao, Zhan, Luczak, Elizabeth D, Stefansdottir, Hrafnhildur, Behunin, Andrew C, Li, Na, El-Accaoui, Ramzi N, Yang, Baoli, Swaminathan, Paari Dominic, Weiss, Robert M, Wehrens, Xander H T, Song, Long-Sheng, Dobrev, Dobromir, Maier, Lars S, Anderson, Mark E

Volltext

Overexpression of CaMKIIδc in RyR2R4496C+/− Knock-In Mice Leads to Altered Intracellular Ca2+ Handling and Increased Mortality von Dybkova, Nataliya, PhD, Sedej, Simon, PhD, Napolitano, Carlo, MD, PhD, Neef, Stefan, MD, Rokita, Adam G., MD, Hünlich, Mark, MD, Brown, Joan Heller, PhD, Kockskämper, Jens, PhD, Priori, Silvia G., MD, PhD, Pieske, Burkert, MD, Maier, Lars S., MD

Volltext

Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias von Pabel, Steffen, Mustroph, Julian, Stehle, Thea, Lebek, Simon, Dybkova, Nataliya, Keyser, Andreas, Rupprecht, Leopold, Wagner, Stefan, Neef, Stefan, Maier, Lars S, Sossalla, Samuel

Volltext

Novel aspects of excitation–contraction coupling in heart failure von Neef, Stefan, Maier, Lars S.

Volltext

Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine von Mustroph, Julian, Baier, Maria J, Unsin, Denise, Provaznik, Zdenek, Kozakov, Kostiantyn, Lebek, Simon, Tarnowski, Daniel, Schildt, Sönke, Voigt, Niels, Wagner, Stefan, Maier, Lars S, Neef, Stefan

Volltext

The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies? von Fischer, Thomas H, Neef, Stefan, Maier, Lars S

Volltext

Cardiac RKIP induces a beneficial β-adrenoceptor–dependent positive inotropy von Schmid, Evelyn, Neef, Stefan, Berlin, Christopher, Tomasovic, Angela, Kahlert, Katrin, Nordbeck, Peter, Deiss, Katharina, Denzinger, Sabrina, Herrmann, Sebastian, Wettwer, Erich, Weidendorfer, Markus, Becker, Daniel, Schäfer, Florian, Wagner, Nicole, Ergün, Süleyman, Schmitt, Joachim P, Katus, Hugo A, Weidemann, Frank, Ravens, Ursula, Maack, Christoph, Hein, Lutz, Ertl, Georg, Müller, Oliver J, Maier, Lars S, Lohse, Martin J, Lorenz, Kristina

Volltext

SR Ca 2+ -leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure von Mustroph, Julian, Wagemann, Olivia, Lebek, Simon, Tarnowski, Daniel, Ackermann, Jasmin, Drzymalski, Marzena, Pabel, Steffen, Schmid, Christof, Wagner, Stefan, Sossalla, Samuel, Maier, Lars S, Neef, Stefan

Volltext

Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation von Meyer-Roxlau, Stefanie, Lämmle, Simon, Opitz, Annett, Künzel, Stephan, Joos, Julius P., Neef, Stefan, Sekeres, Karolina, Sossalla, Samuel, Schöndube, Friedrich, Alexiou, Konstantin, Maier, Lars S., Dobrev, Dobromir, Guan, Kaomei, Weber, Silvio, El-Armouche, Ali

Volltext

Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging von Wittköpper, Katrin, Fabritz, Larissa, Neef, Stefan, Ort, Katharina R, Grefe, Clemens, Unsöld, Bernhard, Kirchhof, Paulus, Maier, Lars S, Hasenfuss, Gerd, Dobrev, Dobromir, Eschenhagen, Thomas, El-Armouche, Ali

Volltext