Isoform-selective targeting of PI3K: time to consider new opportunities? von Cirillo, Davide, Diceglie, Marta, Nazaré, Marc

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Revealing cytotoxic substructures in molecules using deep learning von Webel, Henry E., Kimber, Talia B., Radetzki, Silke, Neuenschwander, Martin, Nazaré, Marc, Volkamer, Andrea

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An Activatable Lanthanide Luminescent Probe for Time‐Gated Detection of Nitroreductase in Live Bacteria von Brennecke, Benjamin, Wang, Qinghua, Zhang, Qingyang, Hu, Hai‐Yu, Nazaré, Marc

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DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells von Brennecke, Benjamin, Wang, Qinghua, Haap, Wolfgang, Grether, Uwe, Hu, Hai-Yu, Nazaré, Marc

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Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer von Carter, David M, Specker, Edgar, Małecki, Piotr H, Przygodda, Jessica, Dudaniec, Krystyna, Weiss, Manfred S, Heinemann, Udo, Nazaré, Marc, Gohlke, Ulrich

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Allosteric Inhibition of a Mammalian Lectin von Aretz, Jonas, Anumala, Upendra R, Fuchsberger, Felix F, Molavi, Narges, Ziebart, Nandor, Zhang, Hengxi, Nazaré, Marc, Rademacher, Christoph

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A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels von Schewe, Marcus, Sun, Han, Mert, Ümit, Mackenzie, Alexandra, Pike, Ashley C W, Schulz, Friederike, Constantin, Cristina, Vowinkel, Kirsty S, Conrad, Linus J, Kiper, Aytug K, Gonzalez, Wendy, Musinszki, Marianne, Tegtmeier, Marie, Pryde, David C, Belabed, Hassane, Nazare, Marc, de Groot, Bert L, Decher, Niels, Fakler, Bernd, Carpenter, Elisabeth P, Tucker, Stephen J, Baukrowitz, Thomas

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Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach von Anumala, Upendra Rao, Waaler, Jo, Nkizinkiko, Yves, Ignatev, Alexander, Lazarow, Katina, Lindemann, Peter, Olsen, Petter Angell, Murthy, Sudarshan, Obaji, Ezeogo, Majouga, Alexander G, Leonov, Sergey, von Kries, Jens Peter, Lehtiö, Lari, Krauss, Stefan, Nazaré, Marc

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Identification and Characterization of a Single High‐Affinity Fatty Acid Binding Site in Human Serum Albumin von Wenskowsky, Lea, Schreuder, Herman, Derdau, Volker, Matter, Hans, Volkmar, Julia, Nazaré, Marc, Opatz, Till, Petry, Stefan

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Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor von Waaler, Jo, Leenders, Ruben G. G, Sowa, Sven T, Alam Brinch, Shoshy, Lycke, Max, Nieczypor, Piotr, Aertssen, Sjoerd, Murthy, Sudarshan, Galera-Prat, Albert, Damen, Eddy, Wegert, Anita, Nazaré, Marc, Lehtiö, Lari, Krauss, Stefan

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Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase von Ruess, Dietrich A., Heynen, Guus J., Ciecielski, Katrin J., Ai, Jiaoyu, Berninger, Alexandra, Kabacaoglu, Derya, Görgülü, Kivanc, Dantes, Zahra, Wörmann, Sonja M., Diakopoulos, Kalliope N., Karpathaki, Angeliki F., Kowalska, Marlena, Kaya-Aksoy, Ezgi, Song, Liang, van der Laan, Eveline A. Zeeuw, López-Alberca, María P., Nazaré, Marc, Reichert, Maximilian, Saur, Dieter, Erkan, Mert M., Hopt, Ulrich T., Sainz, Bruno, Birchmeier, Walter, Schmid, Roland M., Lesina, Marina, Algül, Hana

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Weizhouochrones: Gorgonian-Derived Symmetric Dimers and Their Structure Elucidation Using Anisotropic NMR Combined with DP4+ Probability and CASE-3D von Li, Xiao-Lu, Ru, Tong, Navarro-Vázquez, Armando, Lindemann, Peter, Nazaré, Marc, Li, Xu-Wen, Guo, Yue-Wei, Sun, Han

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A Palladium-Catalyzed Domino Reaction To Access 3‑Amino‑2H‑indazoles from Hydrazines and 2‑Halobenzonitriles von Alsalim, Rana, Lindemann, Peter, López-Alberca, María Pascual, Miksche, Sandra, Czechtizky, Werngard, Halland, Nis, Nazaré, Marc

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Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II von Leenders, Ruben G. G, Brinch, Shoshy Alam, Sowa, Sven T, Amundsen-Isaksen, Enya, Galera-Prat, Albert, Murthy, Sudarshan, Aertssen, Sjoerd, Smits, Johannes N, Nieczypor, Piotr, Damen, Eddy, Wegert, Anita, Nazaré, Marc, Lehtiö, Lari, Waaler, Jo, Krauss, Stefan

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Benzo‐Crown‐Ether Functionalized O‐BODIPY Probes for Cations – A Selective Fluorescent Probe for Ba2 von Sprenger, Tobias, Schwarze, Thomas, Holdt, Hans‐Jürgen, Hentsch, Axel, Nazaré, Marc

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A General One‐Pot Synthesis of 2H‐Indazoles Using an Organophosphorus–Silane System von Schoene, Jens, Bel Abed, Hassen, Schmieder, Peter, Christmann, Mathias, Nazaré, Marc

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Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C‑Type Lectin Langerin von Zhang, Hengxi, Modenutti, Carlos, Nekkanti, Yelha Phani Kumar, Denis, Maxime, Bermejo, Iris A., Lefèbre, Jonathan, Che, Kateryna, Kim, Dongyoon, Kagelmacher, Marten, Kurzbach, Dennis, Nazaré, Marc, Rademacher, Christoph

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Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors von Specker, Edgar, Matthes, Susann, Wesolowski, Radoslaw, Schütz, Anja, Grohmann, Maik, Alenina, Natalia, Pleimes, Dirk, Mallow, Keven, Neuenschwander, Martin, Gogolin, Angelina, Weise, Marie, Pfeifer, Jochen, Ziebart, Nandor, Heinemann, Udo, von Kries, Jens Peter, Nazaré, Marc, Bader, Michael

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Direct Experimental Evidence for Halogen–Aryl π Interactions in Solution from Molecular Torsion Balances von Sun, Han, Horatscheck, André, Martos, Vera, Bartetzko, Max, Uhrig, Ulrike, Lentz, Dieter, Schmieder, Peter, Nazaré, Marc

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Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance von Scipioni, Lucia, Tortolani, Daniel, Ciaramellano, Francesca, Fanti, Federico, Gazzi, Thais, Sergi, Manuel, Nazaré, Marc, Oddi, Sergio, Maccarrone, Mauro

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