The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in Cancer von Pellegrino, Nicole E, Guven, Arcan, Gray, Kayleigh, Shah, Punit, Kasture, Gargi, Nastke, Maria-Dorothea, Thakurta, Anjan, Gesta, Stephane, Vishnudas, Vivek K, Narain, Niven R, Kiebish, Michael A

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Biotransformations with Imine Reductases: Design of a Practical Process Avoiding an Extractive Work‐Up by Entrapment of Water and Enzymes in an Immobilized Phase von Nastke, Alina, Gröger, Harald

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Human CD4+ T Cell Response to Human Herpesvirus 6 von NASTKE, Maria-D, BECERRA, Aniuska, LIUSONG YIN, DOMINGUEZ-AMOROCHO, Omar, GIBSON, Laura, STERN, Lawrence J, CALVO-CALLE, J. Mauricio

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Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis von Thiel, Austin, Yavanian, Gregory, Nastke, Maria-Dorothea, Morales, Peter, Kouris, Nicholas A., Kimbrel, Erin A., Lanza, Robert

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Segmented Flow Processes to Overcome Hurdles of Whole‐Cell Biocatalysis in the Presence of Organic Solvents von Adebar, Niklas, Nastke, Alina, Löwe, Jana, Gröger, Harald

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DDDR-13. OPTIMIZING BRAIN CANCER THERAPY: BALANCING TUMOR ERADICATION AND NORMAL TISSUE PRESERVATION WITH BPM31510 von Khojasteh, Abbas, Kendirli, Mustafa Tansel, Narain, Niven, Nagpal, Seema, Nastke, Maria-Dorothea, Gesta, Stephane, Recht, Lawrence

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Synthetic Study of Dragmacidin E: Enantioselective Construction of the Seven-Membered Ring-Fused Indole Skeleton with Contiguous Stereocenters von Choi, Dongil, Takahashi, Noa, Maruoka, Haruka, Harada, Shingo, Nastke, Alina, Gröger, Harald, Nemoto, Tetsuhiro

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Enhancement of tumor cell susceptibility to natural killer cell activity through inhibition of the PI3K signaling pathway von Bommarito, Davide, Martin, Allison, Forcade, Edouard, Nastke, Maria-Dorothea, Ritz, Jerome, Bellucci, Roberto

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An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma von Clement, Cristina C, Cannizzo, Elvira S, Nastke, Maria-Dorothea, Sahu, Ranjit, Olszewski, Waldemar, Miller, Norman E, Stern, Lawrence J, Santambrogio, Laura

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472P Comprehensive quinomics assessment of BPM31510IV treatment in advanced glioblastoma multiforme patients von Nagpal, S., Henao, J.J., Greenwood, B., Karmacharya, S., Nastke, M-D., Gesta, S., Narain, N.R., Modur, V., Kiebish, M.A., Recht, L.

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SYFPEITHI: Database for Searching and T-Cell Epitope Prediction von Schuler, Mathias M., Nastke, Maria-Dorothea, Stevanović, Stefan

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DDDR-14. IMPROVED ANTI-GLIOBLASTOMA EFFICACY BY BRG399, A NOVEL ORAL MICROTUBULE BINDING AGENT von Kendirli, Mustafa Tansel, Nastke, Maria-Dorothea, Aristizabal-Henao, Juan, Khojasteh, Abbas, Kiebish, Michael, Chimmanamada, Dinesh, Vishnudas, Vivek, Recht, Lawrence, Gesta, Stephane

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Concepts for flow chemistry with whole-cell biocatalysts von Adebar, Niklas, Nastke, Alina, Gröger, Harald

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1551P Validation of response and survival biomarkers in a phase II trial of BPM 31510-IV in advanced refractory pancreatic ductal adenocarcinoma (PDAC) von Subbiah, V., Nastke, M.D., Miller, G.M., Shah, P., Gesta, S., Rodrigues, L.O., Granger, E., Narain, N.R., Kiebish, M.A., Sarangarajan, R., Kundranda, M.N.

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Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection von Calvo-Calle, J Mauricio, Strug, Iwona, Nastke, Maria-Dorothea, Baker, Stephen P, Stern, Lawrence J

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Abstract 2943: Interrogative Biology® platform identifies a novel target in the ubiquitin pathway and its utility in cancer is supported by small molecule modulators von Gesta, Stephane, Sharma, Shefali, Sundararajan, Pragalath, Huang, Mingshu, Gray, Kayleigh, Nastke, Maria, Guven, Arcan, Diers, Anne, Kazerounian, Shiva, Hazarika, Suwagmani, Grund, Eric M., Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad

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Unexpected Abundance of HLA Class II Presented Peptides in Primary Renal Cell Carcinomas von DENGJEL, Jörn, NASTKE, Maria-Dorothea, HENNENLOTTER, Jorg, WERNET, Dorothee, STENZL, Arnulf, RAMMENSEE, Hans-Georg, KLINGEL, Karin, STEVANOVIC, Stefan, GOUTTEFANGEAS, Cécile, GITSIOUDIS, Gitsios, SCHOOR, Oliver, ALTENBEREND, Florian, MÜLLER, Margret, KRÄMER, Björn, MISSIOU, Anna, SAUTER, Martina

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Major contribution of codominant CD8 and CD4 T cell epitopes to the human cytomegalovirus-specific T cell repertoire von Nastke, M-D, Herrgen, L, Walter, S, Wernet, D, Rammensee, H-G, Stevanović, S

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Abstract 703: The anti-cancer drug BPM 31510 elicits immune-modulatory effects through regulation of IL-10 von Dowal, Louisa, Nastke, Maria D., Gaur, Nidhi, Singh, Richa, Fowler, Samantha, Jayashankar, Shyamali, Diers, Anne R., Gesta, Stephane, Vishnudas, Vivek, Narain, Niven R., Sarangarajan, Rangaprasad

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Abstract 1680: BPM31510, an anti-cancer agent selectively causes activation and proliferation of T cells, demonstrating potential utility in an immune-oncology setting von Nastke, Maria-D, Gaur, Nidhi, Dowal, Louisa, Fowler, Samantha, Diers, Anne, Gesta, Stephane, Vishnudas, Vivek K., Narain, Niven R., Sarangarajan, Rangaprasad

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