The role of structural information in the discovery of direct thrombin and factor Xa inhibitors von Nar, Herbert

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Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter von Niu, Yange, Liu, Rui, Guan, Chengcheng, Zhang, Yuan, Chen, Zhixing, Hoerer, Stefan, Nar, Herbert, Chen, Lei

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A specific antidote for dabigatran: functional and structural characterization von Schiele, Felix, van Ryn, Joanne, Canada, Keith, Newsome, Corey, Sepulveda, Eliud, Park, John, Nar, Herbert, Litzenburger, Tobias

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor von Martin, Laetitia J, Koegl, Manfred, Bader, Gerd, Cockcroft, Xiao-Ling, Fedorov, Oleg, Fiegen, Dennis, Gerstberger, Thomas, Hofmann, Marco H, Hohmann, Anja F, Kessler, Dirk, Knapp, Stefan, Knesl, Petr, Kornigg, Stefan, Müller, Susanne, Nar, Herbert, Rogers, Catherine, Rumpel, Klaus, Schaaf, Otmar, Steurer, Steffen, Tallant, Cynthia, Vakoc, Christopher R, Zeeb, Markus, Zoephel, Andreas, Pearson, Mark, Boehmelt, Guido, McConnell, Darryl

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Crystal structure and receptor-interacting residues of MYDGF — a protein mediating ischemic tissue repair von Ebenhoch, Rebecca, Akhdar, Abbas, Reboll, Marc R., Korf-Klingebiel, Mortimer, Gupta, Priyanka, Armstrong, Julie, Huang, Yining, Frego, Lee, Rybina, Irina, Miglietta, John, Pekcec, Anton, Wollert, Kai C., Nar, Herbert

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An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo von Schiele, Felix, Park, John, Redemann, Norbert, Luippold, Gerd, Nar, Herbert

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A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein von Schnapp, Gisela, Hoevels, Yvette, Bakker, Remko A., Schreiner, Patrick, Klein, Thomas, Nar, Herbert

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Protons taken hostage: Dynamic H-bond networks of the pH-sensing GPR68 von Kapur, Bhav, Baldessari, Filippo, Lazaratos, Michalis, Nar, Herbert, Schnapp, Gisela, Giorgetti, Alejandro, Bondar, Ana-Nicoleta

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Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors von Hauel, Norbert H, Nar, Herbert, Priepke, Henning, Ries, Uwe, Stassen, Jean-Marie, Wienen, Wolfgang

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GPR180 is a new member of the Golgi-dynamics domain seven-transmembrane helix protein family von Mitrovic, Sarah-Ana, Demalgiriya-Gamage, Chamalee, Winter, Lisa-Maria, Kiechle, Tobias, Ebenhoch, Rebecca, Neubauer, Heike, Stierstorfer, Birgit, Frego, Lee, Wolfrum, Christian, Reindl, Sophia, Nar, Herbert

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Structural Basis for Photo-induced Protein Cleavage and Green-to-Red Conversion of Fluorescent Protein EosFP von Nienhaus, Karin, Nienhaus, G. Ulrich, Wiedenmann, Jörg, Nar, Herbert, Wolynes, Peter G.

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In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering von Sosa, Yvett, Kapur, Bhav, Hurtak, Jessica, Kingsley, Laura J., Wu, Hao, Gruber, Stefanie, Nar, Herbert, Khattabi, Saad, Moral, Jesus Seco, Lucas, Maria Fátima, Martin, Caterina, Lončar, Nikola, Buono, Frederic, Pefaur, Noah, Nixon, Andrew E., Song, Jinhua J.

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Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis von Rübbelke, Martin, Fiegen, Dennis, Bauer, Margit, Binder, Florian, Hamilton, James, King, Jim, Thamm, Sven, Nar, Herbert, Zeeb, Markus

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A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state von Schnapp, Gisela, Neubauer, Heike, Büttner, Frank H., Handschuh, Sandra, Lingard, Iain, Heilker, Ralf, Klinder, Klaus, Prestle, Jürgen, Walter, Rainer, Wolff, Michael, Zeeb, Markus, Debaene, Francois, Nar, Herbert, Fiegen, Dennis

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Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase‑4 Inhibitors and Their Relationship to Structure von Schnapp, Gisela, Klein, Thomas, Hoevels, Yvette, Bakker, Remko A, Nar, Herbert

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Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain von Rübbelke, Martin, Hamilton, James, Binder, Florian, Bauer, Margit, King, Jim, Nar, Herbert, Zeeb, Markus

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Crystal structures of human and mouse ketohexokinase provide a structural basis for species- and isoform-selective inhibitor design von Ebenhoch, Rebecca, Bauer, Margit, Romig, Helmut, Gottschling, Dirk, Kley, Jörg Thomas, Heine, Niklas, Weber, Alexander, Uphues, Ingo, Nar, Herbert, Pautsch, Alexander

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Photoconvertible Fluorescent Protein EosFP: Biophysical Properties and Cell Biology Applications von Nienhaus, G. Ulrich, Nienhaus, Karin, Hölzle, Angela, Ivanchenko, Sergey, Renzi, Fabiana, Oswald, Franz, Wolff, Michael, Schmitt, Florian, Röcker, Carlheinz, Vallone, Beatrice, Weidemann, Wolfgang, Heilker, Ralf, Nar, Herbert, Wiedenmann, Jörg

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Action of Dipeptidyl Peptidase‐4 Inhibitors on SARS‐CoV‐2 Main Protease von Nar, Herbert, Schnapp, Gisela, Hucke, Oliver, Hardman, Timothy C., Klein, Thomas

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In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A von Cheng, Robert, Huang, Chia‐Ying, Hennig, Michael, Nar, Herbert, Schnapp, Gisela

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