Nanomole-scale high-throughput chemistry for the synthesis of complex molecules von Santanilla, Alexander Buitrago, Regalado, Erik L., Pereira, Tony, Shevlin, Michael, Bateman, Kevin, Campeau, Louis-Charles, Schneeweis, Jonathan, Berritt, Simon, Shi, Zhi-Cai, Nantermet, Philippe, Liu, Yong, Helmy, Roy, Welch, Christopher J., Vachal, Petr, Davies, Ian W., Cernak, Tim, Dreher, Spencer D.

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Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents von Greshock, Thomas J., Moore, Keith P., McClain, Ray T., Bellomo, Ana, Chung, Cheol K., Dreher, Spencer D., Kutchukian, Peter S., Peng, Zhengwei, Davies, Ian W., Vachal, Petr, Ellwart, Mario, Manolikakes, Sophia M., Knochel, Paul, Nantermet, Philippe G.

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Neutralization of Pathogenic Fungi with Small‐Molecule Immunotherapeutics von Chirkin, Egor, Muthusamy, Viswanathan, Mann, Paul, Roemer, Terry, Nantermet, Philippe G., Spiegel, David A.

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Reaction: The Art of Synthetic Chemistry von Nantermet, Philippe G.

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Modeling a Crowdsourced Definition of Molecular Complexity von Sheridan, Robert P, Zorn, Nicolas, Sherer, Edward C, Campeau, Louis-Charles, Chang, Charlie (Zhenyu), Cumming, Jared, Maddess, Matthew L, Nantermet, Philippe G, Sinz, Christopher J, O’Shea, Paul D

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Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group von Bungard, Christopher J, Williams, Peter D, Ballard, Jeanine E, Bennett, David J, Beaulieu, Christian, Bahnck-Teets, Carolyn, Carroll, Steve S, Chang, Ronald K, Dubost, David C, Fay, John F, Diamond, Tracy L, Greshock, Thomas J, Hao, Li, Holloway, M. Katharine, Felock, Peter J, Gesell, Jennifer J, Su, Hua-Poo, Manikowski, Jesse J, McKay, Daniel J, Miller, Mike, Min, Xu, Molinaro, Carmela, Moradei, Oscar M, Nantermet, Philippe G, Nadeau, Christian, Sanchez, Rosa I, Satyanarayana, Tummanapalli, Shipe, William D, Singh, Sanjay K, Truong, Vouy Linh, Vijayasaradhi, Sivalenka, Wiscount, Catherine M, Vacca, Joseph P, Crane, Sheldon N, McCauley, John A

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Discovery of Oxadiazoyl Tertiary Carbinamine Inhibitors of β-Secretase (BACE-1) von Rajapakse, Hemaka A, Nantermet, Philippe G, Selnick, Harold G, Munshi, Sanjeev, McGaughey, Georgia B, Lindsley, Stacey R, Young, Mary Beth, Lai, Ming-Tain, Espeseth, Amy S, Shi, Xiao-Ping, Colussi, Dennis, Pietrak, Beth, Crouthamel, Ming-Chih, Tugusheva, Katherine, Huang, Qian, Xu, Min, Simon, Adam J, Kuo, Lawrence, Hazuda, Daria J, Graham, Samuel, Vacca, Joseph P

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Neutralization of Pathogenic Fungi with Small‐Molecule Immunotherapeutics von Chirkin, Egor, Muthusamy, Viswanathan, Mann, Paul, Roemer, Terry, Nantermet, Philippe G., Spiegel, David A.

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Attenuation of scratch‐induced reactive astrogliosis by novel EphA4 kinase inhibitors von Parmentier‐Batteur, Sophie, Finger, Eleftheria N., Krishnan, Raghu, Rajapakse, Hemaka A., Sanders, John M., Kandpal, Geeta, Zhu, Hong, Moore, Keith P., Regan, Christopher P., Sharma, Sujata, Hess, J. Fred, Williams, Theresa M., Reynolds, Ian J., Vacca, Joseph P., Mark, Robert J., Nantermet, Philippe G.

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Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors von Young, Mary Beth, Barrow, James C, Glass, Kristen L, Lundell, George F, Newton, Christina L, Pellicore, Janetta M, Rittle, Kenneth E, Selnick, Harold G, Stauffer, Kenneth J, Vacca, Joseph P, Williams, Peter D, Bohn, Dennis, Clayton, Franklin C, Cook, Jacquelynn J, Krueger, Julie A, Kuo, Lawrence C, Lewis, S. Dale, Lucas, Bobby J, McMasters, Daniel R, Miller-Stein, Cynthia, Pietrak, Beth L, Wallace, Audrey A, White, Rebecca B, Wong, Bradley, Yan, Youwei, Nantermet, Philippe G

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Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors von Lindsley, Stacey R., Moore, Keith P., Rajapakse, Hemaka A., Selnick, Harold G., Young, Mary Beth, Zhu, Hong, Munshi, Sanjeev, Kuo, Lawrence, McGaughey, Georgia B., Colussi, Dennis, Crouthamel, Ming-Chih, Lai, Ming-Tain, Pietrak, Beth, Price, Eric A., Sankaranarayanan, Sethu, Simon, Adam J., Seabrook, Guy R., Hazuda, Daria J., Pudvah, Nicole T., Hochman, Jerome H., Graham, Samuel L., Vacca, Joseph P., Nantermet, Philippe G.

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Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors von Zhu, Hong, Young, Mary B., Nantermet, Philippe G., Graham, Samuel L., Colussi, Dennis, Lai, Ming-Tain, Pietrak, Beth, Price, Eric A., Sankaranarayanan, Sethu, Shi, Xiao-ping, Tugusheva, Katherine, Holahan, Marie A., Michener, Maria S., Cook, Jacquelynn J., Simon, Adam, Hazuda, Daria J., Vacca, Joseph P., Rajapakse, Hemaka A.

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A facile three-step synthesis of 1,2-amino alcohols using the Ellman homochiral tert-butylsulfinamide von Barrow, James C, Ngo, Phung L, Pellicore, Janetta M, Selnick, Harold G, Nantermet, Philippe G

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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibition von RAJAPAKSE, Hemaka A, NANTERMET, Philippe G, LAI, Ming-Tain, ESPESETH, Amy S, SHI, Xiao-Ping, COLUSSI, Dennis, PIETRAK, Beth, CROUTHAMEL, Ming-Chih, TUGUSHEVA, Katherine, QIAN HUANG, MIN XU, SIMON, Adam J, SELNICK, Harold G, KUO, Lawrence, HAZUDA, Daria J, GRAHAM, Samuel, VACCA, Joseph P, BARROW, James C, MCGAUGHEY, Georgia B, MUNSHI, Sanjeev, LINDSLEY, Stacey R, YOUNG, Mary Beth, NGO, Phung L, KATHERINE HOLLOWAY, M

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Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation von Stauffer, Shaun R., Stanton, Matthew G., Gregro, Alison R., Steinbeiser, Melissa A., Shaffer, Jennifer R., Nantermet, Philippe G., Barrow, James C., Rittle, Kenneth E., Collusi, Dennis, Espeseth, Amy S., Lai, Ming-Tain, Pietrak, Beth L., Holloway, M. Katharine, McGaughey, Georgia B., Munshi, Sanjeev K., Hochman, Jerome H., Simon, Adam J., Selnick, Harold G., Graham, Samuel L., Vacca, Joseph P.

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β-Secretase (BACE-1) inhibitors: Accounting for 10s loop flexibility using rigid active sites von McGaughey, Georgia B., Colussi, Dennis, Graham, Samuel L., Lai, Ming-Tain, Munshi, Sanjeev K., Nantermet, Philippe G., Pietrak, Beth, Rajapakse, Hemaka A., Selnick, Harold G., Stauffer, Shaun R., Holloway, M. Katharine

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The Total Synthesis of (±)-Ginkgolide B von Crimmins, Michael T, Pace, Jennifer M, Nantermet, Philippe G, Kim-Meade, Agnes S, Thomas, James B, Watterson, Scott H, Wagman, Allan S

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Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents von Greshock, Thomas J., Moore, Keith P., McClain, Ray T., Bellomo, Ana, Chung, Cheol K., Dreher, Spencer D., Kutchukian, Peter S., Peng, Zhengwei, Davies, Ian W., Vachal, Petr, Ellwart, Mario, Manolikakes, Sophia M., Knochel, Paul, Nantermet, Philippe G.

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Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P 1 ′ group von Nantermet, Philippe G, Barrow, James C, Lindsley, Stacey R, Young, MaryBeth, Mao, Shi-Shan, Carroll, Steven, Bailey, Carolyn, Bosserman, Michele, Colussi, Dennis, McMasters, Daniel R, Vacca, Joseph P, Selnick, Harold G

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9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors von Stauffer, Kenneth J, Williams, Peter D, Selnick, Harold G, Nantermet, Philippe G, Newton, Christina L, Homnick, Carl F, Zrada, Matthew M, Lewis, S. Dale, Lucas, Bobby J, Krueger, Julie A, Pietrak, Beth L, Lyle, Elizabeth A, Singh, Rominder, Miller-Stein, Cynthia, White, Rebecca B, Wong, Bradley, Wallace, Audrey A, Sitko, Gary R, Cook, Jacquelyn J, Holahan, Marie A, Stranieri-Michener, Maria, Leonard, Yvonne M, Lynch, Joseph J, McMasters, Daniel R, Yan, Youwei

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